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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 31 Jan 2026 | 4 articles | Viewed by 10020 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Therapeutic Potential for Cannabis and Cannabinoids, 3rd Edition

edited by

Wesley M. Raup-Konsavage

submission deadline 31 Jan 2026 | 3 articles | Viewed by 10006 | Submission Open

Keywords: cannabis; tetrahydrocannabinols (THC); cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN); cannabichromene (CBC); pain; cancer; anxiety; PTSD; sleep disorders; neuroprotection; anti-inflammatory

(This special issue belongs to the Section Molecular and Translational Medicine)

Hypertension and Chronic Renal Failure

edited by

Caterina Carollo

submission deadline 31 Jan 2026 | 4 articles | Viewed by 9456 | Submission Open

Keywords: hypertension; chronic renal failure; NephroCardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Triple Negative Breast Cancer: From Mechanisms to Therapeutic Approaches

edited by Emad Rakha and Padmashree Rida

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9216 | Submission Open

Keywords: triple-negative breast cancer; neoadjuvant; adjuvant; chemotherapy; immunotherapy; antibody– drug conjugates; immune checkpoint inhibitors; DNA damage; EGFR; FGFR; microtubule dynamics; centrosome amplification

(This special issue belongs to the Section Cancer Biology and Oncology)

Mitochondrial Dysfunction and Oxidative Stress

edited by

Susana Cardoso

submission deadline 31 Jan 2026 | 2 articles | Viewed by 8755 | Submission Open

Keywords: mitochondria; oxidative stress; brain metabolism; neurodevelopmental diseases; neuropsychiatric diseases; neurodegenerative diseases; mitochondrial medicine; translational medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticle-Based Drug Delivery in Cancer Therapy: Current Progress and Challenges

edited by

Menghuan Tang

and

Zhaoqing Cong

submission deadline 31 Jan 2026 | 3 articles | Viewed by 8711 | Submission Open

Keywords: nanoparticle; targeted drug delivery; controlled release; clinical translation; drug resistance; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering

edited by

Andrei Vasile Nastuta

submission deadline 31 Jan 2026 | 5 articles | Viewed by 8014 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Human Reproductive Biology

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 5 articles | Viewed by 6693 | Submission Open

Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty

(This special issue belongs to the Section Molecular and Translational Medicine)

Medicinal Chemistry in Drug Design and Discovery, 2nd Edition

edited by

Małgorzata Jarończyk

submission deadline 31 Jan 2026 | 3 articles | Viewed by 6542 | Submission Open

Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 Jan 2026 | 1 articles | Viewed by 5928 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Feature Reviews in Infection and Immunity

edited by

Vijay Singh Gondil

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5859 | Submission Open

Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Role of Glycomics in Health and Diseases

edited by

Tijl Vermassen

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5037 | Submission Open

Keywords: glycomics; protein chemistry; tumor immunology; biomarker research

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition

edited by

Wen-Lin Su

, Chih-Hao Shen,

Sheng-Kang Chiu

and

Yi-Ting Chen

submission deadline 31 Jan 2026 | 3 articles | Viewed by 5000 | Submission Open

Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4803 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

PPARs in Health and Disease, 2nd Edition

edited by

Maria Konstandi

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4721 | Submission Open

Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions

edited by

Azizah Ugusman

, Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan

submission deadline 31 Jan 2026 | 4 articles | Viewed by 4587 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

edited by Ilaria Dentamaro

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4402 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Infectious Diseases: Prevention, Diagnosis, and Treatment Under Antimicrobial Resistance Global Urgency

edited by

Célia F. Rodrigues

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4269 | Submission Open

Keywords: AMR; infectious diseases; bacteria; fungi; alternative treatment

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders

edited by Raffaella Cascella

submission deadline 31 Jan 2026 | 4 articles | Viewed by 4190 | Submission Open

Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition)

edited by

Francesco Massari

and

Pietro Scicchitano

submission deadline 31 Jan 2026 | 5 articles | Viewed by 4068 | Submission Open

Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition

edited by

Kan Katayama

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4021 | Submission Open

Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes

edited by

Xian (Phoebe) Zhou

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3956 | Submission Open

Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Genetic Research and Molecular Diagnostics for Hematological Diseases

edited by Ying S. Zou and Leonard N. Yenwongfai

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3878 | Submission Open

Keywords: hematological diseases; genetic research; benign hematology; inherited disorders; next-generation sequencing/long-read sequencing; optical genome mapping; transcriptome; proteomics; digital pathology; deep convolutional neural networks

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition

edited by

Kristina Pilipović

and

Petra Dolenec

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3491 | Submission Open

Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Exploring Potential Therapeutic Compounds with Anti-Inflammatory Activity

edited by Shomaila Mehmood

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3364 | Submission Open

Keywords: green tea polyphenols; isoflavanoids; resveratrol; curcumin; genistein; melatonin; antioxidants; metalloporphyrins; anti-inflammatory compounds

(This special issue belongs to the Section Molecular and Translational Medicine)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3324 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics

edited by Vetriselvan Subramaniyan

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3013 | Submission Open

Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research

(This special issue belongs to the Section Gene and Cell Therapy)

Molecular Mechanisms and Translational Research on Insulin Resistance

edited by

Terisha Ghazi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2975 | Submission Open

Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Recent Advances in Targeted Drug Delivery Systems

edited by

Santosh Bashyal

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2908 | Submission Open

Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

The Molecular Basis of the Immune Response in Pulmonary Fibrosis

edited by

Tamara Cruz

and

Fernanda Hernandez

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2831 | Submission Open

Keywords: immune response; fibrosis; aging; senescence

(This special issue belongs to the Section Immunology and Immunotherapy)

Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition)

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2793 | Submission Open

Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies

edited by

Deepti Diwan

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2374 | Submission Open

Keywords: neurovascular; blood vessels; nervous system; neurological diseases

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Therapeutic Strategies in Gynecological Malignant Tumors—2nd Edition

edited by

Alberto Farolfi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2021 | Submission Open

Keywords: targeted therapy; precision medicine; gynecological cancers; ovarian cancer; endometrial cancer; cervical cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Neural Nexus: Interdisciplinary Perspectives on Neurological Disorders

edited by Gianandrea Traversi,

Marianna Mazza

and Giuseppe Marano

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2011 | Submission Open

Keywords: neurological disorders; mental health; artificial intelligence; machine learning; biomarkers; drug discovery; therapeutic targets; neuroscience research

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Autonomic Disorders: From Mechanisms to Therapeutic Approaches

edited by Svetlana Blitshteyn

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1800 | Submission Open

Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Clinical, Radiological, and Molecular Insights into Craniopharyngioma

edited by Ernest Jan Bobeff and

Bartosz Szmyd

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1672 | Submission Open

Keywords: neuro-oncology; brain tumors; skull base; craniopharyngioma; stalk

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Applications and Developments of Metal-Based Drugs

edited by

Sajal Sen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1544 | Submission Open

Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition

edited by

Maciej Walędziak

and Anna Maria Różańska-Walędziak

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1285 | Submission Open

Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Feature Reviews in Ophthalmology

edited by

Ana Maria Dascalu

submission deadline 31 Jan 2026 | 2 articles | Viewed by 1267 | Submission Open

Keywords: glaucoma; retinal diseases; diabetic retinopathy; age-related macular degeneration; retinitis pigmentosa; Leber's congenital amaurosis; ocular surface pathology

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1050 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Technologies in the Diagnosis and Management of Neurological Disorders

edited by

Luca Filippi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 958 | Submission Open

Keywords: neurological disorders; advanced diagnostic imaging modalities; neurophysiological tools

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 31 Jan 2026 | 1 articles | Viewed by 956 | Submission Open

Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition

edited by

Da-Wen Lu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 905 | Submission Open

Keywords: glaucoma; ocular pharmacology; ocular disease

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (3rd Edition)

edited by

Susana Coimbra

and

Alice Santos-Silva

submission deadline 31 Jan 2026 | 1 articles | Viewed by 866 | Submission Open

Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment

(This special issue belongs to the Section Cell Biology and Pathology)

Genetically Determined Cardiovascular Disease

edited by

Gaetano Thiene

submission deadline 31 Jan 2026 | 1 articles | Viewed by 841 | Submission Open

Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation

edited by Chao Liu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 829 | Submission Open

Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells

(This special issue belongs to the Section Immunology and Immunotherapy)

Atrial Fibrillation: From Pathogenesis to Treatment Strategies

edited by

Dimitrios A. Vrachatis

, Theodore G. Papaioannou and

Ioannis Anagnostopoulos

submission deadline 31 Jan 2026 | 1 articles | Viewed by 784 | Submission Open

Keywords: atrial fibrillation; arrhythmia; ablation; PFA; radiofrequency; cryoablation; pathophysiology; pathophysiology; molecular mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation

edited by

Huifang Tang

submission deadline 31 Jan 2026 | 1 articles | Viewed by 565 | Submission Open

Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Biomaterials for Tissue Repair and Regeneration

edited by Fei Xing, Wen Nie and Zhao Chen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 535 | Submission Open

Keywords: biomaterials; nanomaterials; tissue repair; 3D printing; functionals biomaterials; biomaterial science; tissue regeneration

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advancements and Challenges in Anticancer Targeted Therapy with Small Molecules

edited by Monika Papiez

submission deadline 31 Jan 2026 | Viewed by 461 | Submission Open

Keywords: small molecules; cancer; anticancer targeted therapy; cancer resistance; cancer growth blockers

(This special issue belongs to the Section Cancer Biology and Oncology)

Displaying special issue 201-250 on page 5 of 16.

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