Atrial Fibrillation: From Pathogenesis to Treatment Strategies
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 29
Special Issue Editors
2. Department of Biomedical Engineering, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece
Interests: atrial fibrillation; electrophysiology; cardiology; biomedical engineering; medical technology; digital medicine
Special Issues, Collections and Topics in MDPI journals
Interests: cardiology; cardiovascular medicine; biomechanics biomedical engineering; medical technology; digital medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Atrial fibrillation (AF) is the most common sustained arrhythmia associated with substantial morbidity and mortality. It increases the risk of stroke, heart failure, and hospitalizations and is marked by frequent recurrence and progression. Despite advances in pharmacological and interventional therapies, the complex and multifactorial nature of AF—encompassing structural, electrical, and inflammatory pathways—continues to pose significant clinical challenges.
This Special Issue of Biomedicines invites original research and reviews focused on the mechanisms and treatment of atrial fibrillation (AF). We welcome studies exploring atrial remodeling, inflammation, fibrosis, ion channel dysfunction, and electrical instability, as well as predictors of progression and recurrence. Research spanning basic, translational, and clinical domains is encouraged.
Of particular interest are investigations that shed light on the underlying pathogenesis of AF, from molecular and cellular pathways to tissue-level and organ-level remodeling. Contributions assessing emerging pharmacologic agents, novel antiarrhythmic approaches, and advanced interventional strategies—such as catheter ablation and hybrid therapies—are highly valued.
By integrating multidisciplinary insights, this issue aims to advance our understanding of atrial fibrillation (AF) pathophysiology and support the development of more effective, durable, and personalized treatment approaches.
We look forward to your contributions to this focused and timely issue.
Dr. Dimitrios A. Vrachatis
Prof. Dr. Theodore G. Papaioannou
Dr. Ioannis Anagnostopoulos
Guest Editors
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Keywords
- atrial fibrillation
- arrhythmia
- ablation
- PFA
- radiofrequency
- cryoablation
- pathophysiology
- pathophysiology
- molecular mechanisms
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