Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 135

Special Issue Editors

1. Division of Pulmonary and Critical Care Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No.289, Jianguo Rd., Xindian Dist., New Taipei City 23142, Taiwan
2. School of Medicine, Tzu Chi University, Hualien, No.289, Jianguo Rd., Xindian Dist., New Taipei City 23142, Taiwan
Interests: sepsis; COVID-19; biomarkers; pneumonia
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Guest Editor
Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan
Interests: acute lung injury; macrophages; alveolar epithelium

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Guest Editor
1. Division of Infectious Diseases, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation. No. 289, Jianguo Rd., Xindian Dist., New Taipei City 23142, Taiwan
2. School of Medicine, Tzu Chi University, Hualien. No. 289, Jianguo Rd., Xindian Dist., New Taipei City 23142, Taiwan
Interests: antimicrobial resistance; klebsiella pneumoniae; sepsis; virulence
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Guest Editor
1. Department of Critical Care Medicine, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien City, Taiwan
2. School of Medicine, Tzu Chi University, Hualien. No. 707, Sec. 3, Zhongyang Rd., Hualien City 970473, Taiwan
Interests: sepsis; critical care; tuberculosis; pneumonia
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Special Issue Information

Dear Colleagues,

Sepsis is a life-threatening condition arising from a dysregulated host response to infection, and it remains a critical global health challenge. Its progression often leads to multiple organ dysfunction and significant morbidity and mortality. The pathophysiology of sepsis involves a complex interplay between immune cells, platelets, and other host systems, which work together to combat pathogens but can also result in severe inflammation and organ damage.

Currently, the clinical diagnosis of sepsis relies on the Sequential Organ Failure Assessment (SOFA) score, which measures the severity of organ failure. However, the identification of molecular biomarkers—released either by the host or the pathogen during infection—has opened new avenues for understanding sepsis progression, enhancing diagnostic accuracy, and guiding the development of more effective therapeutic interventions.

We invite you to contribute original research articles, reviews, or short communications that explore recent advances in molecular biomarkers and their role in defining sepsis severity, improving diagnostic methods, and developing more efficient therapies. Submissions addressing signal transduction mechanisms, inflammatory pathways, pathogen–host interactions, and innovative therapeutic approaches are particularly welcome.

Dr. Wen-Lin Su
Dr. Chih-Hao Shen
Dr. Sheng-Kang Chiu
Dr. Yi-Ting Chen
Guest Editors

Manuscript Submission Information

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Keywords

  • sepsis
  • organ dysfunction
  • inflammatory process
  • molecular biomarkers
  • pathogen infection
  • signal transduction mechanisms

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Published Papers

This special issue is now open for submission.
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