Recent Advances in Targeted Drug Delivery Systems
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Drug Discovery, Development and Delivery".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 1082
Special Issue Editor
Interests: drug delivery; lipid nanocarriers; polymeric nanocarriers; targeted delivery systems; 3D printing; cancer/molecular imaging
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Despite significant advancements in drug delivery systems, clinical applications continue to face challenges that require innovative solutions to enhance therapeutic efficacy. Targeted drug delivery systems have emerged as a promising approach to address issues such as poor solubility, rapid clearance, low stability, and severe side effects, all of which limit the therapeutic potential of many active compounds and clinical medications. To maximize clinical applications and patient compliance, advanced pharmaceutical technologies such as encapsulation, solid dispersions, nanotechnology, and targeted delivery systems have proven successful in improving medication stability, lowering toxicity, and increasing efficacy.
Lipid/polymeric membrane-based systems—such as liposomes, nanoparticles, polymeric vesicles, dendrimers, and micelles—have shown significant promise in addressing unmet therapeutic needs by encapsulating medications, enhancing stability, and enabling controlled release. Additionally, exosomes, which are endogenous nanosized vesicles, offer great potential for targeted drug delivery due to their exceptional biocompatibility, ability to cross biological barriers, innate targeting properties, and tumor-homing capabilities. These systems hold implications for regenerative medicine, neurological disorders, cardiovascular diseases, infectious illnesses, and cancer treatment, presenting opportunities to improve targeted therapies and amplify their therapeutic efficacy.
Another important development in the field is theranostic drug delivery systems, which combine diagnosis and treatment. Recent progress in targeted drug delivery systems highlights a growing focus on novel formulation technologies, nanotechnology, and theranostic approaches. By enhancing therapeutic efficacy, safety, and patient compliance, these advancements hope to open the door to more individualized and efficient treatment alternatives for a range of medical applications.
Dr. Santosh Bashyal
Guest Editor
Manuscript Submission Information
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Keywords
- targeted drug delivery systems
- nanocarriers (lipid or polymeric)
- stimuli-responsive carriers
- exosomes or exosome-mimetic vesicles
- disease targeting
- tumor targeting
- theranostics
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