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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Reviews in Cytokines

edited by

Monika Zajkowska

submission deadline 30 Jan 2026 | 2 articles | Viewed by 2312 | Submission Open

Keywords: cytokines; neurodegenerative disease; cancer; diabetes; obesity; immunological disorder; cardiovascular disease; diagnosis; biomarker; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms of Cell Death in Cancer Cells: A New Therapeutic Opportunity—2nd Edition

edited by

Adrian-Bogdan Țigu

submission deadline 31 Jan 2026 | 6 articles | Viewed by 17702 | Submission Open

Keywords: cell death; drug repositioning; translational research; oncology; cancer therapy; apoptosis

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiovascular and Metabolic Disease: New Treatment and Future Directions—4th Edition

edited by

Alfredo Caturano

submission deadline 31 Jan 2026 | 12 articles | Viewed by 16207 | Submission Open

Keywords: cardiovascular disease; metabolic disease; diabetes; therapy; drugs; implantable device; heart failure; heart transplantation; cardiac surgery; future directions

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Biomarkers in Inflammatory Bowel Disease: Pathophysiology and New Therapeutic Strategies—Second Edition

edited by

Marino Vilović

submission deadline 31 Jan 2026 | 5 articles | Viewed by 16046 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; biomarkers; molecular biomarkers in IBD; pathophysiology; therapeutic approaches in IBD; precision medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Research of Neurodegenerative and Psychiatric Diseases, 2nd Edition

edited by

Dubravka Švob Štrac

submission deadline 31 Jan 2026 | 6 articles | Viewed by 11981 | Submission Open

Keywords: neurodegenerative disorders; psychiatric diseases; biomarkers; therapeutic targets; omics approaches; molecular pathways; cell biology; animal models; clinical studies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Mechanisms and Novel Therapies for Brain Injury: 2nd Edition

edited by

Arjun Sapkota

submission deadline 31 Jan 2026 | 5 articles | Viewed by 9671 | Submission Open

Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood– brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Therapeutic Potential for Cannabis and Cannabinoids, 3rd Edition

edited by

Wesley M. Raup-Konsavage

submission deadline 31 Jan 2026 | 3 articles | Viewed by 9288 | Submission Open

Keywords: cannabis; tetrahydrocannabinols (THC); cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN); cannabichromene (CBC); pain; cancer; anxiety; PTSD; sleep disorders; neuroprotection; anti-inflammatory

(This special issue belongs to the Section Molecular and Translational Medicine)

Hypertension and Chronic Renal Failure

edited by

Caterina Carollo

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8658 | Submission Open

Keywords: hypertension; chronic renal failure; NephroCardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Triple Negative Breast Cancer: From Mechanisms to Therapeutic Approaches

edited by Emad Rakha and Padmashree Rida

submission deadline 31 Jan 2026 | 5 articles | Viewed by 8526 | Submission Open

Keywords: triple-negative breast cancer; neoadjuvant; adjuvant; chemotherapy; immunotherapy; antibody– drug conjugates; immune checkpoint inhibitors; DNA damage; EGFR; FGFR; microtubule dynamics; centrosome amplification

(This special issue belongs to the Section Cancer Biology and Oncology)

Mitochondrial Dysfunction and Oxidative Stress

edited by

Susana Cardoso

submission deadline 31 Jan 2026 | 2 articles | Viewed by 8439 | Submission Open

Keywords: mitochondria; oxidative stress; brain metabolism; neurodevelopmental diseases; neuropsychiatric diseases; neurodegenerative diseases; mitochondrial medicine; translational medicine

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 31 Jan 2026 | 4 articles | Viewed by 8434 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticle-Based Drug Delivery in Cancer Therapy: Current Progress and Challenges

edited by

Menghuan Tang

and

Zhaoqing Cong

submission deadline 31 Jan 2026 | 3 articles | Viewed by 8389 | Submission Open

Keywords: nanoparticle; targeted drug delivery; controlled release; clinical translation; drug resistance; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering

edited by

Andrei Vasile Nastuta

submission deadline 31 Jan 2026 | 5 articles | Viewed by 7617 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy

(This special issue belongs to the Section Molecular and Translational Medicine)

Medicinal Chemistry in Drug Design and Discovery, 2nd Edition

edited by

Małgorzata Jarończyk

submission deadline 31 Jan 2026 | 3 articles | Viewed by 6084 | Submission Open

Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

New Advances in Human Reproductive Biology

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 5 articles | Viewed by 5804 | Submission Open

Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Infection and Immunity

edited by

Vijay Singh Gondil

submission deadline 31 Jan 2026 | 2 articles | Viewed by 5210 | Submission Open

Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 Jan 2026 | 1 articles | Viewed by 5093 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition

edited by

Wen-Lin Su

, Chih-Hao Shen,

Sheng-Kang Chiu

and

Yi-Ting Chen

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4613 | Submission Open

Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4500 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

PPARs in Health and Disease, 2nd Edition

edited by

Maria Konstandi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4497 | Submission Open

Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Role of Glycomics in Health and Diseases

edited by

Tijl Vermassen

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4473 | Submission Open

Keywords: glycomics; protein chemistry; tumor immunology; biomarker research

(This special issue belongs to the Section Molecular and Translational Medicine)

Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics

edited by Ilaria Dentamaro

submission deadline 31 Jan 2026 | 3 articles | Viewed by 4033 | Submission Open

Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Infectious Diseases: Prevention, Diagnosis, and Treatment Under Antimicrobial Resistance Global Urgency

edited by

Célia F. Rodrigues

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3985 | Submission Open

Keywords: AMR; infectious diseases; bacteria; fungi; alternative treatment

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders

edited by Raffaella Cascella

submission deadline 31 Jan 2026 | 4 articles | Viewed by 3903 | Submission Open

Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes

edited by

Xian (Phoebe) Zhou

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3817 | Submission Open

Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions

edited by

Azizah Ugusman

, Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan

submission deadline 31 Jan 2026 | 4 articles | Viewed by 3740 | Submission Open

Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition)

edited by

Francesco Massari

and

Pietro Scicchitano

submission deadline 31 Jan 2026 | 4 articles | Viewed by 3468 | Submission Open

Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Genetic Research and Molecular Diagnostics for Hematological Diseases

edited by Ying S. Zou and Leonard N. Yenwongfai

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3383 | Submission Open

Keywords: hematological diseases; genetic research; benign hematology; inherited disorders; next-generation sequencing/long-read sequencing; optical genome mapping; transcriptome; proteomics; digital pathology; deep convolutional neural networks

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition

edited by

Kristina Pilipović

and

Petra Dolenec

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3292 | Submission Open

Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition

edited by

Kan Katayama

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3267 | Submission Open

Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte

(This special issue belongs to the Section Molecular and Translational Medicine)

Exploring Potential Therapeutic Compounds with Anti-Inflammatory Activity

edited by Shomaila Mehmood

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3039 | Submission Open

Keywords: green tea polyphenols; isoflavanoids; resveratrol; curcumin; genistein; melatonin; antioxidants; metalloporphyrins; anti-inflammatory compounds

(This special issue belongs to the Section Molecular and Translational Medicine)

Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition

edited by

Farhad Vahid

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3029 | Submission Open

Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

The Molecular Basis of the Immune Response in Pulmonary Fibrosis

edited by

Tamara Cruz

and

Fernanda Hernandez

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2721 | Submission Open

Keywords: immune response; fibrosis; aging; senescence

(This special issue belongs to the Section Immunology and Immunotherapy)

Recent Advances in Targeted Drug Delivery Systems

edited by

Santosh Bashyal

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2670 | Submission Open

Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Mechanisms and Translational Research on Insulin Resistance

edited by

Terisha Ghazi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2441 | Submission Open

Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition)

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2399 | Submission Open

Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics

edited by Vetriselvan Subramaniyan

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2393 | Submission Open

Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research

(This special issue belongs to the Section Gene and Cell Therapy)

Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies

edited by

Deepti Diwan

submission deadline 31 Jan 2026 | 2 articles | Viewed by 2254 | Submission Open

Keywords: neurovascular; blood vessels; nervous system; neurological diseases

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Therapeutic Strategies in Gynecological Malignant Tumors—2nd Edition

edited by

Alberto Farolfi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1930 | Submission Open

Keywords: targeted therapy; precision medicine; gynecological cancers; ovarian cancer; endometrial cancer; cervical cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Neural Nexus: Interdisciplinary Perspectives on Neurological Disorders

edited by Gianandrea Traversi,

Marianna Mazza

and Giuseppe Marano

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1798 | Submission Open

Keywords: neurological disorders; mental health; artificial intelligence; machine learning; biomarkers; drug discovery; therapeutic targets; neuroscience research

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Clinical, Radiological, and Molecular Insights into Craniopharyngioma

edited by Ernest Jan Bobeff and

Bartosz Szmyd

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1599 | Submission Open

Keywords: neuro-oncology; brain tumors; skull base; craniopharyngioma; stalk

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Applications and Developments of Metal-Based Drugs

edited by

Sajal Sen

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1426 | Submission Open

Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition

edited by

Maciej Walędziak

and Anna Maria Różańska-Walędziak

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1190 | Submission Open

Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Autonomic Disorders: From Mechanisms to Therapeutic Approaches

edited by Svetlana Blitshteyn

submission deadline 31 Jan 2026 | 1 articles | Viewed by 1132 | Submission Open

Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Ophthalmology

edited by

Ana Maria Dascalu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 980 | Submission Open

Keywords: glaucoma; retinal diseases; diabetic retinopathy; age-related macular degeneration; retinitis pigmentosa; Leber's congenital amaurosis; ocular surface pathology

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition

edited by

Tomislav Bulum

submission deadline 31 Jan 2026 | 1 articles | Viewed by 976 | Submission Open

Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis

(This special issue belongs to the Section Cell Biology and Pathology)

Emerging Technologies in the Diagnosis and Management of Neurological Disorders

edited by

Luca Filippi

submission deadline 31 Jan 2026 | 1 articles | Viewed by 875 | Submission Open

Keywords: neurological disorders; advanced diagnostic imaging modalities; neurophysiological tools

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition

edited by

Da-Wen Lu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 860 | Submission Open

Keywords: glaucoma; ocular pharmacology; ocular disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition

edited by

Tomislav Bulum

and

Martina Tomić

submission deadline 31 Jan 2026 | 1 articles | Viewed by 845 | Submission Open

Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation

edited by Chao Liu

submission deadline 31 Jan 2026 | 1 articles | Viewed by 764 | Submission Open

Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells

(This special issue belongs to the Section Immunology and Immunotherapy)

Displaying special issue 201-250 on page 5 of 15.

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