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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neural Plasticity: Mechanisms and Therapeutic Implications

edited by Linlin Sun

submission deadline 30 Nov 2026 | 1 articles | Viewed by 3715 | Submission Open

Keywords: neural plasticity; synaptic plasticity; neurogenesis; neural regeneration; brain injury; non-invasive brain stimulation techniques

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Advances in Oral Pathology and Medicine

edited by

Christian Bacci

submission deadline 30 Nov 2026 | 4 articles | Viewed by 3670 | Submission Open

Keywords: molecular diagnostics; imaging technologies; artificial intelligence; targeted therapies; regenerative medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Brain Disorders: Bridging Molecular Insights and Innovative Therapies

edited by

Karol Wiśniewski

and

Bartosz Szmyd

submission deadline 30 Nov 2026 | 1 articles | Viewed by 3508 | Submission Open

Keywords: neurosurgery; neuro-oncology; glioma; innovations; cancer predisposing syndrome; neurofibromatosis; CMMRD

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Research on Spermatozoa and Male Infertility: From Molecular Mechanism to Therapeutic Perspectives

edited by

Francesca Paola Luongo

and

Alice Luddi

submission deadline 30 Nov 2026 | 2 articles | Viewed by 3319 | Submission Open

Keywords: spermatozoa biology; molecular mechanisms of spermatogenesis; oxidative stress and sperm function; therapeutic strategies for addressing male infertility

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Biomarkers for Neurodegenerative Diseases: From Molecular Discovery to Early Diagnosis

edited by

Sujung Yeo

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2941 | Submission Open

Keywords: alpha-synuclein; neurodegeneration; Parkinson's disease; pathophysiology; mechanism; therapy; synucleinopathy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Cardiac Remodeling

edited by Silvio Assis de Oliveira-Junior and André Soares Leopoldo

submission deadline 30 Nov 2026 | 3 articles | Viewed by 2895 | Submission Open

Keywords: cardiac remodeling; cardiomyocyte contractile; obesity; diabetes; diets; training; rats; humans

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Natural and Synthetic Anticancer Agents: Mechanistic Insights and Translational Pathways

edited by

Gul-E-Saba Chaudhry

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2883 | Submission Open

Keywords: cancer; drug discovery; synthetic anti-cancer; natural bioactive compounds; nano targeted targeted drug delivery; cancer biomarkers; mechanism of cell death; novel anti-cancer compounds

(This special issue belongs to the Section Cancer Biology and Oncology)

State-of-the-Art Drug Discovery and Development in Poland (3rd Edition)

edited by

Aleksandra Romaniuk-Drapała

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2778 | Submission Open

Keywords: in silico drug target profiling; drug delivery systems; drug–drug interaction; target-based screening; phenotypic screening; pharmaceutical modeling; computational chemistry; targeted therapy; biomarkers; bioimaging

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Autoimmune and Inflammatory Disorders: From Pathogenesis to Therapeutic Targeting

edited by

Yu-Wei Chang

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2490 | Submission Open

Keywords: inflammasome; inflammation; sepsis; autoimmune; microbiota; immunomodulation

(This special issue belongs to the Section Immunology and Immunotherapy)

Kidney Disease: From Pathophysiology to Treatment

edited by

Paola Pontrelli

and

Francesca Conserva

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2282 | Submission Open

Keywords: acute kidney injury; chronic kidney disease; precision medicine; molecular mechanisms; biomarkers; therapeutic response

Brain Tumor: From Pathophysiology to Novel Therapies

edited by

Paulo Linhares

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2186 | Submission Open

Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance

(This special issue belongs to the Section Cancer Biology and Oncology)

Biomaterials and Nanotechnology for Advanced Wound Dressings

edited by Javad Esmaeili

submission deadline 30 Nov 2026 | 2 articles | Viewed by 2112 | Submission Open

Keywords: wound dressings; wound healing; biomaterials and nanotechnology; regenerative medicine; targeted delivery

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Pyroptosis and Cellular Stress: Emerging Mechanisms and Therapeutic Targets

edited by Gang Du

submission deadline 30 Nov 2026 | 1 articles | Viewed by 2040 | Submission Open

Keywords: pyroptosis; cellular stress; ROS; programmed cell death; gasdermin; cytokines; inflammation; infection; cellular metabolism; immunometabolism

(This special issue belongs to the Section Cell Biology and Pathology)

Natural Products and Their Pharmacological Activity

edited by Klinger Antonio da Franca Rodrigues

submission deadline 30 Nov 2026 | 3 articles | Viewed by 1998 | Submission Open

Keywords: natural products; pharmacological activity; drug discovery; bioactive compounds; medicinal chemistry; inflammation; infectious diseases; nanoformulations; metabolomics; sustainable biodiversity

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advanced Research on Heart Failure and Heart Transplantation (2nd Edition)

edited by

Nandan Kumar Mondal

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1948 | Submission Open

Keywords: heart failure; heart transplantation; DBD (donation after brain death); DCD (donation after cardiac death); cardiac arrest; ischemic time and reperfusion injury; myocardial damage; preservation techniques; post-transplant outcomes

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights in Thyroid Cancer

edited by

Rodis D. Paparodis

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1864 | Submission Open

Keywords: thyroid carcinoma; molecular diagnostics; targeted therapy; genetic mutations; radioiodine therapy; radiofrequency ablation therapy; active surveillance; precision oncology

(This special issue belongs to the Section Molecular and Translational Medicine)

Cancer Pharmacology

edited by Zhi Shi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1678 | Submission Open

Keywords: cancer pharmacology; anticancer drug; cancer chemotherapy; targeted therapy; cancer immunotherapy; combination therapy; drug resistance

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

High-Risk Atrial Fibrillation in Patients with Cardiovascular Disease: Diagnosis, Comprehensive Risk Assessment, Comorbidities, and Anticoagulation Strategies

edited by

Silvia Reverté-Villarroya

and

José-Luis Clúa-Espuny

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1616 | Submission Open

Keywords: atrial fibrillation; cardiovascular comorbidity; device-detected atrial fibrillation; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Recent Advances in Diagnosis and Therapeutic Strategies in Intraocular Inflammation—Second Edition

edited by

Uwe Pleyer

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1485 | Submission Open

Keywords: biomarker; diagnosis; immune pharmacology; immune regulation; immune system; infection; uveitis; therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Liver Cancer: Molecular and Translational Insights of Carcinogenesis and Treatments

edited by

Joon Hyuk Choi

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1455 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; intrahepatic cholangiocarcinoma; carcinogenesis; premalignant lesions; diagnosis; pathology; treatment

(This special issue belongs to the Section Cancer Biology and Oncology)

Advanced Nanomaterials and Nanotechnology for Precision Biomedicine and Drug Delivery

edited by Sanjeev Rambharose

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1431 | Submission Open

Keywords: nanomedicine; drug delivery systems; lipid nanoparticles; polymeric nanoparticles; targeted therapy; controlled release; nano-biosensors; stimuli-responsive nanomaterials; nanotoxicology; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advances in Chronic Respiratory System Diseases: From Bench to Bedside

edited by Paolo Cameli

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1299 | Submission Open

Keywords: severe asthma; COPD; bronchiectasis; translational medicine; molecular biomarkers; interstitial lung diseases; immunobiology; omics; prognosis; pathogenesis; genetics

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Cancer Biology and Experimental Anticancer Therapies (3rd Edition)

edited by

Letizia Polito

and

Ewa Gajda

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1285 | Submission Open

Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

Imaging Technology for Human Diseases: 2nd Edition

edited by Emanuele David

submission deadline 30 Nov 2026 | 2 articles | Viewed by 1180 | Submission Open

Keywords: technological advances; imaging; X-ray; mammography; CT; MRI; ultrasound; angiography

(This special issue belongs to the Section Biomedical Engineering and Materials)

Natural and Synthetic Molecules with Anticancer Activity: Pharmacological Basis and Mechanistic Insight—2nd Edition

edited by

Hassan Ebrahim

and

Angela-Patricia Hernández

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1155 | Submission Open

Keywords: anticancer; molecular pharmacology; mechanistic mode of action; signal transduction; in vitro; preclinical; natural products; synthesis

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Emerging Trends in Reproductive Endocrinology and Pregnancy-Related Disorders

edited by

Theodoros Kalampokas

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1123 | Submission Open

Keywords: pregnancy-related disorders; eclampsia; preeclampsia; hypertensive disorders of pregnancy; gestational diabetes; reproductive endocrinology; precision medicine

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Clinical and Translational Advances in Neuro-Ophthalmology

edited by Hyun-jin Shin

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1098 | Submission Open

Keywords: neuro-ophthalmology; translational medicine; optic neuropathy; ocular motility disorders; visual pathway disorders; neuroimaging and electrophysiology; biomarkers in vision science; gene and stem cell therapy; artificial intelligence in neuro-ophthalmology; clinical trials in vision disorders

(This special issue belongs to the Section Molecular and Translational Medicine)

Clinical Pathology in Cancer: From Diagnosis to Precision Medicine

edited by

Georgia Levidou

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1038 | Submission Open

Keywords: cancer biomarkers; precision medicine; histopathology; clinical pathology; diagnosis; prognostic/predictive biomarker

(This special issue belongs to the Section Cell Biology and Pathology)

Novel Biomaterials and Tissue Engineering Approaches in Periodontal Regeneration

edited by

Federico Mussano

submission deadline 30 Nov 2026 | 1 articles | Viewed by 1028 | Submission Open

Keywords: periodontium; tissue engineering; regenerative medicine; biomaterials; bioprinting; mesenchymal stem/stromal cells; senescence; aging; advanced therapeutics

(This special issue belongs to the Section Biomedical Engineering and Materials)

Glioblastoma: Molecular and Immune Pathology for the Development of Novel Therapies

edited by

Rodney Luwor

and

Farah Ahmady-Nield

submission deadline 30 Nov 2026 | 1 articles | Viewed by 854 | Submission Open

Keywords: glioblastoma; tumor microenvironment; immunotherapy; crosstalk; treatment; cancer

(This special issue belongs to the Section Cancer Biology and Oncology)

Imaging and Modeling Alzheimer's Disease: The Quest for Mechanistic Understanding, Early Diagnosis, and Novel Treatments

edited by Guoshi Li

submission deadline 30 Nov 2026 | Viewed by 659 | Submission Open

Keywords: biomarker identification; connectome analysis; computational neuroimaging; biophysical modeling; network models; machine learning; brain stimulation; neurodegeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Mechanisms of Drug Resistance in Cancers

edited by

Guohui Wan

and

Heng Liang

submission deadline 30 Nov 2026 | 1 articles | Viewed by 611 | Submission Open

Keywords: cancer drug resistance; molecular mechanisms; tumor microenvironment; cancer immunity; apoptosis evasion; metabolic reprogramming; epigenetic regulation; proteomic reprogramming; combination therapies

(This special issue belongs to the Section Cancer Biology and Oncology)

Precision Medicine Through Functional Drug Screening and Disease Modeling

edited by

Mantang Qiu

submission deadline 30 Nov 2026 | Viewed by 505 | Submission Open

Keywords: precision medicine; functional drug screening; patient-derived models; organoids and 3D cultures; translational therapeutics; disease modelling

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Correlative Light and Electron Microscopy (CLEM) in Biomedicine: Advances and Applications

edited by

Hideya Kawasaki

submission deadline 30 Nov 2026 | Viewed by 503 | Submission Open

Keywords: CLEM; correlative microscopy; biomedicine; pathology; virology; oncology; immunolabeling; cryo-microscopy; ultrastructure; image analysis

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Pulmonary Hypertension

edited by

Katya Rigatto

submission deadline 30 Nov 2026 | 1 articles | Viewed by 490 | Submission Open

Keywords: pulmonary hypertension; vascular remodeling; right ventricular dysfunction; oxidative stress; inflammation; molecular pathways; intestinal microbiota; biomarkers; experimental models; translational research; innovative therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

Nanoparticles in Biomedical Engineering: From Drug Delivery to Tissue Engineering

edited by Jia Nong

submission deadline 30 Nov 2026 | Viewed by 488 | Submission Open

Keywords: nanoparticle; nanomedicine; nanoconjugates; drug delivery; biomaterials; wound healing; angiogenesis; antimicrobial agents; regenerative medicine; theranostics

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Multimodal Brain Imaging in Clinical Practice

edited by Fares Al-Shargie

submission deadline 30 Nov 2026 | Viewed by 451 | Submission Open

Keywords: multimodal neuroimaging; magnetic resonance imaging (MRI); diffusion tensor imaging (DTI); electroencephalography (EEG); functional near-infrared spectroscopy (fNIRS); neuroimaging biomarkers; clinical translation; precision medicine; brain connectivity and machine learning in neuroimaging

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Innovative Strategies for the Diagnosis and Treatment of Sarcopenia and Osteoporosis

edited by Wei-Bin Hsu and

Meng-Huang Wu

submission deadline 30 Nov 2026 | Viewed by 450 | Submission Open

Keywords: sarcopenia; osteoporosis; healthy aging; bone strength; muscle health; fracture prevention; pharmacological therapies; nutritional support; exercise rehabilitation

(This special issue belongs to the Section Molecular and Translational Medicine)

Generative Artificial Intelligence in Biomedical Sciences: Transforming Research, Diagnosis, and Therapy

edited by Iman Tavassoly

submission deadline 30 Nov 2026 | Viewed by 440 | Submission Open

Keywords: artificial intelligence; biomedical data; generative models; machine learning; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Cellular and Molecular Biology of Neurodegenerative Disorders, 2nd Edition

edited by

Marta Lualdi

submission deadline 30 Nov 2026 | Viewed by 424 | Submission Open

Keywords: neurodegeneration; omics; biomarkers; systems biology; disease-modifying therapies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Muscular Dystrophy: From Mechanisms to Therapeutic Approaches

edited by

Gisela Gaina

and Marco A.F. Fernandes

submission deadline 30 Nov 2026 | Viewed by 395 | Submission Open

Keywords: muscular dystrophy; genetic diseases; muscle regeneration; therapeutic approaches; molecular diagnosis; in vitro and in vivo models

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Artificial Intelligence in Cancer Imaging: Advancing Precision Oncology

edited by Farhan Akram

submission deadline 30 Nov 2026 | Viewed by 390 | Submission Open

Keywords: artificial intelligence; cancer imaging; digital pathology; machine learning; deep learning; radiomics; tumor characterization; precision oncology; biomarker discovery; clinical translation

(This special issue belongs to the Section Cancer Biology and Oncology)

Encephalitis and Viral Infection: Mechanisms and Therapies—2nd Edition

edited by Bradley S. Hollidge and

Samantha S. Soldan

submission deadline 30 Nov 2026 | Viewed by 364 | Submission Open

Keywords: neurovirology; encephalitis; gene therapy; viral vectors; virology; immunology; neuroscience; gene editing; neuroinflammation; arboviruses; innate immunity

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Microbiota and Immunity in Cancers

edited by

Davide Frumento

submission deadline 30 Nov 2026 | Viewed by 359 | Submission Open

Keywords: immunology; cancer; microbiota; immunotherapy; probiotics; oncology

(This special issue belongs to the Section Molecular and Translational Medicine)

Female Fertility: Insights from Molecular Perspective

edited by Sofoklis Stavros and

Anastasios Potiris

submission deadline 30 Nov 2026 | Viewed by 336 | Submission Open

Keywords: ovarian senescence; oocyte mitochondrial dynamics; reproductive immunology; male and female infertility; recurrent pregnancy loss (RPL); recurrent implantation failure (RIF); assisted reproductive technologies (ART); early pregnancy; bioinformatics; artificial intelligence (AI)

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetic and Post-Translational Regulations of Cancer Cell Fate: Metabolism, Plasticity, and Therapeutics

edited by

Changmin Peng

submission deadline 30 Nov 2026 | Viewed by 328 | Submission Open

Keywords: epigenetic regulation; post-translational modifications; cancer cell fate; cancer metabolism; tumor plasticity; signal transduction in cancer; epigenetic therapeutics; targeted cancer therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Shaping the Future of ILD Care: Novel Diagnostic Technologies and Their Clinical Impact

edited by

Francesco Amati

submission deadline 30 Nov 2026 | Viewed by 309 | Submission Open

Keywords: interstitial lung diseases (ILDs); personalized medicine; precision medicine; diagnostic modalities; genomic classifiers; advanced imaging; photon-counting CT

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis, Diagnosis and Treatment of Rheumatoid Arthritis and Osteoarthritis

edited by

Shih-Yao Chen

submission deadline 30 Nov 2026 | Viewed by 298 | Submission Open

Keywords: rheumatoid arthritis; osteoarthritis; inflammaging; microRNA; synovial inflammation; cartilage degeneration; biomarkers; regenerative medicine; gene therapy; disease modeling

(This special issue belongs to the Section Molecular and Translational Medicine)

Integrating Multimodal Data, Artificial Intelligence, and Bioinformatics for Precision Medicine and Drug Development

edited by

Weikaixin Kong

and

Zhengwei Xie

submission deadline 30 Nov 2026 | Viewed by 295 | Submission Open

Keywords: multi-omics analysis; artificial intelligence; machine learning; deep learning; drug development; bioinformatics; cancer genomics

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Recent Advances in Diagnosis, Therapeutics, and Mechanistic Research of Multiple Myeloma

edited by Xiaoqing Dong

submission deadline 30 Nov 2026 | Viewed by 280 | Submission Open

Keywords: multiple myeloma; diagnosis; therapeutics; mechanistic research; drug resistance; tumor microenvironment; biomarker; therapeutic target

(This special issue belongs to the Section Cancer Biology and Oncology)

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