Special Issue "Discovery and Development of Constrained Peptide Ligands"
A special issue of Biomedicines (ISSN 2227-9059).
Deadline for manuscript submissions: closed (30 June 2018).
Constrained peptide ligands often exhibit exquisite target affinity and selectivity, making them appealing candidates for novel drug discovery and development. Unlike smaller molecules, constrained peptides are capable of modulating protein–protein interactions, making them amenable to targeting the so-called “undruggabe” proteome. Additionally, the intermediate size of constrained peptides relative to small molecules and larger biologics (e.g., antibodies), means that constrained peptides can, in some cases, simultaneously exhibit the benefits of both, with small molecule-like pharmacology and antibody-like specificity and affinity.
We invite research and review papers in the fields of constrained peptide ligand discovery and development, including articles describing macrocyclic peptides, stapled peptides, disulfide constrained peptides, constrained peptide pharmacology and studies of constrained peptide structure–activity relationships.
Prof. Dr. Hiroaki Suga
Dr. Toby Passioura
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- constrained peptide
- macrocyclic peptide
- stapled peptide
- peptide pharmacology
- peptide structure–activity relationship
- protein–protein interaction inhibition