Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Molecular Research of Neurodegenerative and Psychiatric Diseases, 2nd Edition submission deadline 31 Jan 2026 | 6 articles | Viewed by 12458 | Submission Open
Keywords: neurodegenerative disorders; psychiatric diseases; biomarkers; therapeutic targets; omics approaches; molecular pathways; cell biology; animal models; clinical studies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Mechanisms and Novel Therapies for Brain Injury: 2nd Edition
edited by
submission deadline 31 Jan 2026 | 5 articles | Viewed by 10143 | Submission Open
Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood– brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Therapeutic Potential for Cannabis and Cannabinoids, 3rd Edition submission deadline 31 Jan 2026 | 3 articles | Viewed by 9944 | Submission Open
Keywords: cannabis; tetrahydrocannabinols (THC); cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN); cannabichromene (CBC); pain; cancer; anxiety; PTSD; sleep disorders; neuroprotection; anti-inflammatory
(This special issue belongs to the Section Molecular and Translational Medicine)
Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches
edited by Natalia Rozas and Cameron Jeter
submission deadline 31 Jan 2026 | 4 articles | Viewed by 9873 | Submission Open
Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system 
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Hypertension and Chronic Renal Failure
edited by
submission deadline 31 Jan 2026 | 4 articles | Viewed by 9398 | Submission Open
Keywords: hypertension; chronic renal failure; NephroCardiology
(This special issue belongs to the Section Molecular and Translational Medicine)
Triple Negative Breast Cancer: From Mechanisms to Therapeutic Approaches
edited by Emad Rakha and Padmashree Rida
submission deadline 31 Jan 2026 | 5 articles | Viewed by 9169 | Submission Open
Keywords: triple-negative breast cancer; neoadjuvant; adjuvant; chemotherapy; immunotherapy; antibody– drug conjugates; immune checkpoint inhibitors; DNA damage; EGFR; FGFR; microtubule dynamics; centrosome amplification
(This special issue belongs to the Section Cancer Biology and Oncology)
Mitochondrial Dysfunction and Oxidative Stress
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 8730 | Submission Open
Keywords: mitochondria; oxidative stress; brain metabolism; neurodevelopmental diseases; neuropsychiatric diseases; neurodegenerative diseases; mitochondrial medicine; translational medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Nanoparticle-Based Drug Delivery in Cancer Therapy: Current Progress and Challenges submission deadline 31 Jan 2026 | 3 articles | Viewed by 8691 | Submission Open
Keywords: nanoparticle; targeted drug delivery; controlled release; clinical translation; drug resistance; nanomedicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering submission deadline 31 Jan 2026 | 5 articles | Viewed by 7997 | Submission Open
Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Human Reproductive Biology submission deadline 31 Jan 2026 | 5 articles | Viewed by 6623 | Submission Open
Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty
(This special issue belongs to the Section Molecular and Translational Medicine)
Medicinal Chemistry in Drug Design and Discovery, 2nd Edition submission deadline 31 Jan 2026 | 3 articles | Viewed by 6511 | Submission Open
Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Parkinson’s Disease: Where Are We and Where Are We Going To
edited by Carmen Borrué
submission deadline 31 Jan 2026 | 1 articles | Viewed by 5859 | Submission Open
Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Feature Reviews in Infection and Immunity
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 5799 | Submission Open
Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity
(This special issue belongs to the Section Immunology and Immunotherapy)
Role of Glycomics in Health and Diseases
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 4992 | Submission Open
Keywords: glycomics; protein chemistry; tumor immunology; biomarker research
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition
edited by , Chih-Hao Shen, and
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4956 | Submission Open
Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Neonatal Medicine in Japan
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4780 | Submission Open
Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use
(This special issue belongs to the Section Molecular and Translational Medicine)
PPARs in Health and Disease, 2nd Edition
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 4669 | Submission Open
Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Cardiovascular Diseases: Pathophysiological Insights, Therapeutic Strategies and Future Directions
edited by , Wan Amir Nizam Wan Ahmad and Dharmani Devi Murugan
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4515 | Submission Open
Keywords: cardiovascular disease; pathophysiology; therapeutic strategies; translational research; complementary medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Cardiac Imaging: Diagnostics, Prognostics, and Therapeutics
edited by Ilaria Dentamaro
submission deadline 31 Jan 2026 | 3 articles | Viewed by 4379 | Submission Open
Keywords: cardiac imaging; echocardiography; cardiovascular magnetic resonance imaging; cardio CT; nuclear cardiology
(This special issue belongs to the Section Molecular and Translational Medicine)
Infectious Diseases: Prevention, Diagnosis, and Treatment Under Antimicrobial Resistance Global Urgency submission deadline 31 Jan 2026 | 3 articles | Viewed by 4246 | Submission Open
Keywords: AMR; infectious diseases; bacteria; fungi; alternative treatment
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders
edited by Raffaella Cascella
submission deadline 31 Jan 2026 | 4 articles | Viewed by 4177 | Submission Open
Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Cardiac and Vascular Diseases: Pathogenesis, Pharmacological Treatments, Advances in Therapies (3rd Edition) submission deadline 31 Jan 2026 | 5 articles | Viewed by 4019 | Submission Open
Keywords: endothelial function; cardiomyopathies; cardiovascular pharmacology; cardiac therapeutics; noninvasive vascular treatments; molecular cardiac biomarkers; molecular vascular biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Nephrotic Syndrome: Pathomechanism, Diagnostics and Novel Treatment Options—2nd Edition
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 3956 | Submission Open
Keywords: focal segmental glomerulosclerosis; genetic kidney disease; minimal change disease; nephrotic syndrome; podocyte
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 3947 | Submission Open
Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Genetic Research and Molecular Diagnostics for Hematological Diseases
edited by Ying S. Zou and Leonard N. Yenwongfai
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3822 | Submission Open
Keywords: hematological diseases; genetic research; benign hematology; inherited disorders; next-generation sequencing/long-read sequencing; optical genome mapping; transcriptome; proteomics; digital pathology; deep convolutional neural networks
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Brain Injury: New Insights into Mechanisms and Future Promising Treatments—Second Edition submission deadline 31 Jan 2026 | 2 articles | Viewed by 3473 | Submission Open
Keywords: acquired brain injury; nanomedicine; nanotechnology; neuroregenerative therapy; neurorepair; new and emerging treatments; pharmacotherapy; stroke; tissue engineering; traumatic brain injury
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Exploring Potential Therapeutic Compounds with Anti-Inflammatory Activity
edited by Shomaila Mehmood
submission deadline 31 Jan 2026 | 2 articles | Viewed by 3348 | Submission Open
Keywords: green tea polyphenols; isoflavanoids; resveratrol; curcumin; genistein; melatonin; antioxidants; metalloporphyrins; anti-inflammatory compounds
(This special issue belongs to the Section Molecular and Translational Medicine)
Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development—3rd Edition
edited by
submission deadline 31 Jan 2026 | 3 articles | Viewed by 3295 | Submission Open
Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition
(This special issue belongs to the Section Molecular and Translational Medicine)
Exosomes in Medicine: Recent Advances in Drug Delivery, Diagnostics, and Therapeutics
edited by Vetriselvan Subramaniyan
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2941 | Submission Open
Keywords: exosomes; drug delivery; diagnostics; therapeutics; precision medicine; biomarkers; nanomedicine; inflammation and neurodegeneration; exosome engineering; translational research
(This special issue belongs to the Section Gene and Cell Therapy)
Molecular Mechanisms and Translational Research on Insulin Resistance
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2930 | Submission Open
Keywords: insulin resistance; type 2 diabetes mellitus; metabolic syndrome; insulin signaling; inflammation; oxidative stress; mitochondrial dysfunction; epigenetics; epitranscriptomics (e.g.; m6A RNA methylation); biomarkers; translational medicine; therapeutic targets
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Recent Advances in Targeted Drug Delivery Systems
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2888 | Submission Open
Keywords: targeted drug delivery systems; nanocarriers (lipid or polymeric); stimuli-responsive carriers; exosomes or exosome-mimetic vesicles; disease targeting; tumor targeting; theranostics
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
The Molecular Basis of the Immune Response in Pulmonary Fibrosis submission deadline 31 Jan 2026 | 2 articles | Viewed by 2825 | Submission Open
Keywords: immune response; fibrosis; aging; senescence
(This special issue belongs to the Section Immunology and Immunotherapy)
Pathogenesis, Diagnostics and Therapeutics in Obsterics and Gynaecology (2nd Edition) submission deadline 31 Jan 2026 | 2 articles | Viewed by 2762 | Submission Open
Keywords: gynaecology; obstetrics; diagnosis; pathogenesis; treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Neurovascular Dysfunction: Mechanisms and Therapeutic Strategies
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 2367 | Submission Open
Keywords: neurovascular; blood vessels; nervous system; neurological diseases
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advances in Therapeutic Strategies in Gynecological Malignant Tumors—2nd Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 2016 | Submission Open
Keywords: targeted therapy; precision medicine; gynecological cancers; ovarian cancer; endometrial cancer; cervical cancer
(This special issue belongs to the Section Cancer Biology and Oncology)
Neural Nexus: Interdisciplinary Perspectives on Neurological Disorders
edited by Gianandrea Traversi, and Giuseppe Marano
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1979 | Submission Open
Keywords: neurological disorders; mental health; artificial intelligence; machine learning; biomarkers; drug discovery; therapeutic targets; neuroscience research
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Autonomic Disorders: From Mechanisms to Therapeutic Approaches
edited by Svetlana Blitshteyn
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1734 | Submission Open
Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics
(This special issue belongs to the Section Molecular and Translational Medicine)
Clinical, Radiological, and Molecular Insights into Craniopharyngioma
edited by Ernest Jan Bobeff and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1671 | Submission Open
Keywords: neuro-oncology; brain tumors; skull base; craniopharyngioma; stalk
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Applications and Developments of Metal-Based Drugs
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1538 | Submission Open
Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus—2nd Edition
edited by and Anna Maria Różańska-Walędziak
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1278 | Submission Open
Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Feature Reviews in Ophthalmology
edited by
submission deadline 31 Jan 2026 | 2 articles | Viewed by 1189 | Submission Open
Keywords: glaucoma; retinal diseases; diabetic retinopathy; age-related macular degeneration; retinitis pigmentosa; Leber's congenital amaurosis; ocular surface pathology
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Insulin—100 Years Since Its Discovery: 2nd Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 1048 | Submission Open
Keywords: insulin action; insulin analogs; type 1 diabetes; type 2 diabetes; complications; glucose homeostasis
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Technologies in the Diagnosis and Management of Neurological Disorders
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 956 | Submission Open
Keywords: neurological disorders; advanced diagnostic imaging modalities; neurophysiological tools
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Research and Recent Advances in Diabetic Retinopathy—3rd Edition submission deadline 31 Jan 2026 | 1 articles | Viewed by 943 | Submission Open
Keywords: diabetes; diabetic retinopathy; complications; vascular endothelial growth factor; retina; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Glaucoma: New Diagnostic and Therapeutic Approaches, 3rd Edition
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 904 | Submission Open
Keywords: glaucoma; ocular pharmacology; ocular disease
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (3rd Edition) submission deadline 31 Jan 2026 | 1 articles | Viewed by 858 | Submission Open
Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment
(This special issue belongs to the Section Cell Biology and Pathology)
The Renin–Angiotensin System in Immune Regulation: Roles in Blood, Vessels, and Inflammation
edited by Chao Liu
submission deadline 31 Jan 2026 | 1 articles | Viewed by 828 | Submission Open
Keywords: renin– angiotensin system; immune regulation; vascular biology; inflammation; T cells; macrophages; neutrophils; angiotensin II; ACE2; stem cells
(This special issue belongs to the Section Immunology and Immunotherapy)
Genetically Determined Cardiovascular Disease
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 823 | Submission Open
Keywords: genetically determined cardiovascular diseases; genetic mutations; oligogenic inheritance; congenital heart defects; atherosclerosis
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Atrial Fibrillation: From Pathogenesis to Treatment Strategies
edited by , Theodore G. Papaioannou and
submission deadline 31 Jan 2026 | 1 articles | Viewed by 780 | Submission Open
Keywords: atrial fibrillation; arrhythmia; ablation; PFA; radiofrequency; cryoablation; pathophysiology; pathophysiology; molecular mechanisms
(This special issue belongs to the Section Molecular and Translational Medicine)
Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation
edited by
submission deadline 31 Jan 2026 | 1 articles | Viewed by 561 | Submission Open
Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models
(This special issue belongs to the Section Molecular and Translational Medicine)
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