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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Contribution of Neural Stemness and Its Regulatory Networks to Tumorigenesis

edited by

Ying Cao

submission deadline 28 Feb 2026 | Viewed by 13 | Submission Open

Keywords: neural stemness; tumorigenicity; pluripotency; phenotypic heterogeneity; cancer cell; cancer cell-intrinsic neural factors; differentiation therapy via targeting neural stemness; tumorigenesis; therapy resistance; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

Emerging Trends in Dental Caries: Insights into Etiology, Risk Factors, and Treatment Strategies (2nd Edition)

edited by

Hee-Eun Kim

submission deadline 28 Feb 2026 | Viewed by 9 | Submission Open

Keywords: antimicrobial effect; demineralization; dental caries; dental plaque; oral biofilm; oral disease; oral management; pathogenicity; prevention; remineralization

(This special issue belongs to the Section Microbiology in Human Health and Disease)

State of the Art in Mitochondrial Research

edited by

Jan Ježek

submission deadline 28 Feb 2026 | Viewed by 9 | Submission Open

Keywords: mitochondrial metabolism; bioenergetics; mitochondrial signaling; mitochondrial dynamics; reactive oxygen species; apoptosis; hypoxia; mitochondrial genetics; mitochondrial diseases; aging

(This special issue belongs to the Section Cell Biology and Pathology)

Novel Biomarkers and Precision Medicine in Gynecologic Malignancies

edited by Zheng Feng

submission deadline 28 Feb 2026 | Viewed by 9 | Submission Open

Keywords: clinical trials; genomic landscape; targeted therapy; liquid biopsy; tumor screening; biomarker research; artificial intelligence

(This special issue belongs to the Section Cancer Biology and Oncology)

Liquid Biopsy in Tumor

edited by Heidi Fettke

submission deadline 28 Feb 2026 | Viewed by 7 | Submission Open

Keywords: cfDNA; ctDNA; liquid biopsy; solid tumors; fragmentomics; MRD; cancer genomics; non-invasive biomarkers; treatment resistance; precision oncology

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Diagnosis and Therapeutic Strategies in Intraocular Inflammation—Second Edition

edited by

Uwe Pleyer

submission deadline 28 Feb 2026 | Viewed by 6 | Submission Open

Keywords: biomarker; diagnosis; immune pharmacology; immune regulation; immune system; infection; uveitis; therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Fertility and Reproductive Health: Understanding of Reproductive Physiology and Pathology

edited by Sevastiani Antonouli and

Valentina Di Nisio

submission deadline 28 Feb 2026 | Viewed by 5 | Submission Open

Keywords: female infertility; male infertility; oocyte quality; embryo implantation; follicular dynamics; gamete and embryo ultrastructure; assisted reproduction technologies; reproductive aging; fertility preservation; oncofertility challenges

(This special issue belongs to the Section Gene and Cell Therapy)

Neuroimmunology and Neurological Infection

edited by Mariya Ivanovska

submission deadline 28 Feb 2026 | Viewed by 4 | Submission Open

Keywords: neuroimmunology; neurological infections; immune-mediated diseases; neurodegeneration; biomarkers; immunotherapy; neuroinflammation; clinical neurology

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Decoding Resistance: Molecular Drivers of Therapy Failure in Advanced Prostate Cancer

edited by

Jyoti Kaushal

submission deadline 28 Feb 2026 | Viewed by 2 | Submission Open

Keywords: prostate cancer; androgen deprivation therapy; molecular signaling; epigenetic remodeling; cancer stem cell; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Channelopathies: Drug Interactions and Clinical Advances

edited by Cesar Celis Ceballos

submission deadline 28 Feb 2026 | Submission Open

Keywords: electrophysiology; ion channels; channelopathies; drugs; patch-clamp

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advances in Liver Fibrosis: From Mechanisms to Therapeutics

edited by

Kun Zhang

submission deadline 28 Feb 2026 | Submission Open

Keywords: liver fibrosis; therapeutic target; biomarker; hepatocyte; macrophage; LSEC; HSC; immune cells; extracellular matrix

(This special issue belongs to the Section Molecular and Translational Medicine)

New Advances in Pulmonary Fibrosis

edited by

Mari Ozaki

submission deadline 28 Feb 2026 | Submission Open

Keywords: pulmonary fibrosis; interstitial lung disease; antifibrotic therapy; precision medicine; imaging diagnostics; novel therapeutics; pathobiology; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights in Immunological Pathways

edited by

Wan-Chung Hu

submission deadline 28 Feb 2026 | Submission Open

Keywords: immune response; immune signal pathway; cytokine storm

(This special issue belongs to the Section Immunology and Immunotherapy)

Laser Applications in Medicine: Current Status and Emerging Challenges

edited by Irit Juwiler

submission deadline 16 Mar 2026 | Viewed by 144 | Submission Open

Keywords: lasers; medicine; surgery; dermatology; ophthalmology; dentistry; otolaryngology; gastroenterology; urology; gynecology; cardiology; neurosurgery; orthopedics; tissue types; biological interactions; technological advancements; clinical applications; health outcomes

(This special issue belongs to the Section Biomedical Engineering and Materials)

Biomarkers in Pain: 2nd Edition

edited by

Mats B. Eriksson

and

Anders O. Larsson

submission deadline 30 Mar 2026 | Viewed by 36 | Submission Open

Keywords: analgesia; biomarker; CSF; cytokine; inflammation; neuropathy; neurotransmitter; pain; QoL; sensitization; sensory

(This special issue belongs to the Section Molecular and Translational Medicine)

Genetic and Epigenetic Research on Kidney Diseases

edited by Hailong Hu

submission deadline 30 Mar 2026 | Viewed by 26 | Submission Open

Keywords: kidney disease; genetics; epigenetics; DNA methylation; non-coding RNAs; precision medicine; therapeutic target; nephrology

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Metabolic Dysfunction-Associated Steatotic Disease

edited by Junzhao Ye

submission deadline 30 Mar 2026 | Viewed by 2 | Submission Open

Keywords: metabolic dysfunction-associated fatty liver disease; metabolic dysfunction-associated steatotic disease; novel classification using proteomic and metabolomic profiles; new kinds of lifestyle modification interventions; especially for nutrition interventions; radiologic advances in steatosis; inflammation; and fibrosis assessments; artificial intelligence applications; therapeutic innovations; microbiota

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Long COVID: Mechanisms, Biomarkers, and Treatment

edited by

Frédérique Ponchel

submission deadline 31 Mar 2026 | 3 articles | Viewed by 10504 | Submission Open

Keywords: long-COVID; clinical observations; disease mechanism; biomarkers; treatment strategies; opinions

(This special issue belongs to the Section Cell Biology and Pathology)

Clinical Electrophysiology for Precision Diagnosis for Cardiology and Central Nervous System Diseases

edited by

Fátima Regina Mena Barreto Silva

and

Diana Marcela Aragon Novoa

submission deadline 31 Mar 2026 | 3 articles | Viewed by 8073 | Submission Open

Keywords: brain; cardiology; precision medicine.

(This special issue belongs to the Section Molecular and Translational Medicine)

Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated

edited by

Consolato M. Sergi

and

Paola Di Carlo

submission deadline 31 Mar 2026 | 4 articles | Viewed by 5159 | Submission Open

Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

New Approaches to Spinal Cord-Related Diseases

edited by Corentin Dauleac

submission deadline 31 Mar 2026 | Viewed by 29 | Submission Open

Keywords: spinal cord; spinal cord injury; stem cell; neuromodulation; rehabilitation; plasticity; spasticity; pain; neuroimaging

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Oxidative Stress, Mitochondrial Dysfunction, and Aβ Pathology: Converging Pathways in Aging and Neurodegeneration

edited by

Swapnil Pandey

, Laxmi Rathor and

Ashish Shukla

submission deadline 31 Mar 2026 | Viewed by 26 | Submission Open

Keywords: oxidative stress; aging; amyloid beta; tau phosphorylation; neurodegeneration; regulated cell death; mitochondrial biogenesis; Drosophila; C. elegans

(This special issue belongs to the Section Cell Biology and Pathology)

Fibromyalgia and Neuroinflammation: Unraveling Pathophysiological Links and Therapeutic Targets

edited by Mario García-Domínguez

submission deadline 31 Mar 2026 | Viewed by 25 | Submission Open

Keywords: fibromyalgia; neuroinflammation; central sensitization; glial activation; cytokines; pain modulation; chronic pain; neuroimmune interaction

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Imaging and Modeling Alzheimer's Disease: The Quest for Mechanistic Understanding, Early Diagnosis, and Novel Treatments

edited by Guoshi Li

submission deadline 31 Mar 2026 | Viewed by 16 | Submission Open

Keywords: biomarker identification; connectome analysis; computational neuroimaging; biophysical modeling; network models; machine learning; brain stimulation; neurodegeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Stem Cell Biology and Tissue Engineering for Cardiology

edited by Otilia Țica

submission deadline 31 Mar 2026 | Viewed by 14 | Submission Open

Keywords: cardiac regeneration; stem cell therapy; cardiac tissue engineering; mesenchymal stem cells (MSCs); induced pluripotent stem cells (iPSCs); cardiomyocyte differentiation; myocardial repair; 3D bioprinting; biomaterials in cardiology; cardiac scaffolds; heart organoids; translational regenerative medicine; cell-based therapy; cardiovascular bioengineering; immunomodulation in cardiac repair

(This special issue belongs to the Section Molecular and Translational Medicine)

Emerging Trends in Liver Diseases and Cirrhosis Research

edited by

Hariklia Kranidioti

submission deadline 31 Mar 2026 | Viewed by 12 | Submission Open

Keywords: pathogenesis of liver fibrosis and cirrhosis; MASLD; hepatitis B; C and D; primary biliary cholangitis (PBC): immunopathology and treatment advances; alcohol-associated liver disease; liver regeneration and stem-cell-based therapies; biomarkers for early diagnosis and prognosis; emerging antifibrotic treatments; liver complications and systemic comorbidities; personalized medicine in liver disease

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Skin Diseases

edited by Nazia M. Saiyed and

Noriko Aramaki-Hattori

submission deadline 31 Mar 2026 | Viewed by 11 | Submission Open

Keywords: skin diseases; dermatology; diagnostic innovations; targeted therapies; molecular mechanisms; immunodermatology; translational research; inflammatory skin disorders; clinical dermatology; precision medicine

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovations in Radiation Oncology

edited by

Caressa Hui

submission deadline 31 Mar 2026 | Viewed by 10 | Submission Open

Keywords: adaptive radiotherapy; cancer biomarkers; genomics; artificial intelligence; radiation oncology; machine learning; precision oncology; radiogenomics; ctDNA

(This special issue belongs to the Section Cancer Biology and Oncology)

Decoding Neurodegeneration: Insights From Multi-Omics and Neuroimaging Integration

edited by

Abdulhakim Al-Ezzi

submission deadline 31 Mar 2026 | Viewed by 9 | Submission Open

Keywords: neurodegenerative; neuroimaging; executive functions; electrophysiology; brain connectivity; multi omics data; bio-molecular data; biomarkers; systems biology; single-cell omics; translational neuroscience

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Emerging Trends and Applications in Nanomedicine and Targeted Therapies

edited by

Marzieh Ramezani Farani

submission deadline 31 Mar 2026 | Viewed by 6 | Submission Open

Keywords: nanomedicine; drug delivery systems; targeted therapy; biomaterials; cancer therapy; smart nanocarriers; biodegradable nanoparticles; photothermal therapy; nano-diagnostics; translational nanotechnology

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Leishmaniasis: Pathophysiology, Diagnostics and Current and Emerging Therapeutic Approaches—2nd Edition

edited by Raimunda Nonata Ribeiro Sampaio

submission deadline 31 Mar 2026 | Viewed by 3 | Submission Open

Keywords: leishmaniasis; pathophysiology; neglected infectious diseases

(This special issue belongs to the Section Molecular and Translational Medicine)

Head and Neck Cancer: Molecular Mechanisms to Therapeutic Advances

edited by Jacopo Zocchi, Irene H. Nauta and

Carlos M. Chiesa-Estomba

submission deadline 31 Mar 2026 | Viewed by 2 | Submission Open

Keywords: head and neck cancer; molecular mechanisms; molecular biomarkers; immunotherapy; liquid biopsy; treatment resistance; targeted therapies; precision medicine

(This special issue belongs to the Section Cancer Biology and Oncology)

Inflammatory Mechanisms, Biomarkers and Treatment in Oral Diseases

edited by

Raquel M. Scarel-Caminaga

submission deadline 31 Mar 2026 | Viewed by 1 | Submission Open

Keywords: periodontal diseases; peri-implantitis; oral lichen planus; oral microbial dysbiosis; inflammatory pathways; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Morpho-Molecular and Genetic Basis of Cardiomyopathies

edited by

Andrea Frustaci

submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open

Keywords: dilated cardiomyopathy; hypertrophic cardiomyopathy; restrictive cardiomyopathy; inflammatory cardiomyopathy; myocardial storage diseases; genetic investigations

(This special issue belongs to the Section Molecular and Translational Medicine)

Breast Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatments

edited by Ioanna Akrida

submission deadline 30 Jun 2026 | Viewed by 5 | Submission Open

Keywords: breast cancer carcinogenesis; triple-negative breast cancer (TNBC); HER2; endocrine therapy; neoadjuvant chemotherapy (NACT); immunotherapy; tumor profiling molecular tests; liquid biopsy circulating tumor cells (CTCs); circulating tumor DNA (ctDNA)

(This special issue belongs to the Section Cancer Biology and Oncology)

Biomedical Applications of Microfluidics

edited by

Surjendu Maity

submission deadline 31 Jul 2026 | Submission Open

Keywords: microfluidics; organ-on-a-chip; lab-on-a-chip; disease modeling; regenerative medicine; cancer immunotherapy; biosensors; mathematical modeling; AI/ML; realtime sensing

(This special issue belongs to the Section Biomedical Engineering and Materials)

Displaying special issue 701-750 on page 15 of 15.

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