Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advances in Cancer Treatment submission deadline 31 May 2027 | 2 articles | Viewed by 2450 | Submission Open
Keywords: targeted therapy; bio-conjugates; biologic agents; precision oncology; personalized cancer treatment; biomarker-guided therapy; cancer drug development; biopharmaceuticals
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Neurophysiology and the Treatment of Parkinson’s Disease
edited by
submission deadline 31 May 2027 | 2 articles | Viewed by 2385 | Submission Open
Keywords: movement disorders; hypokinetic movement disorders; Parkinson’s disease; levodopa; treatment; neurophysiology; neuroplasticity; motor learning
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advanced Development on Lipid Nanoparticles
edited by
submission deadline 31 May 2027 | 2 articles | Viewed by 1994 | Submission Open
Keywords: lipid nanoparticles; nanomedicine; drug delivery systems; mRNA delivery; gene therapy; lipid-based carriers; nanoparticle formulation; targeted delivery; vaccine technology; pharmaceutical nanotechnology
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Periodontal Disease: From Pathophysiology to Novel Therapeutic Approaches—2nd Edition
edited by
submission deadline 31 May 2027 | 2 articles | Viewed by 1724 | Submission Open
Keywords: periodontal disease; oral microbiome; dysbiosis; artificial intelligence (AI); personalized therapeutic interventions
(This special issue belongs to the Section Molecular and Translational Medicine)
Insights into Retinal Development, Disease, and Neuroprotection with Pharmacologic and Perioperative Considerations
edited by Siyuan Song
submission deadline 31 May 2027 | 1 articles | Viewed by 1669 | Submission Open
Keywords: retinal development; retinal degeneration; diabetic retinopathy; glaucoma/optic neuropathy; neuroprotection; neuroinflammation; microglia; single-cell/spatial omics; retinal organoids; anesthesia and analgesia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Cardiac Arrhythmias and Arrhythmogenic Disorders: Pathomechanisms, Diagnostics and Novel Treatment Options
edited by Michela Casella and
submission deadline 31 May 2027 | 2 articles | Viewed by 1600 | Submission Open
Keywords: arrhythmias; arrhythmogenic disorders; cardiomyopathies; genetics; cardiac MRI; atrial fibrillation; premature ventricular contraction; ventricular tachycardia; catheter ablation
(This special issue belongs to the Section Molecular and Translational Medicine)
Exploring Bioactive Metabolites and Immunomodulatory Potential in Natural Products
edited by
submission deadline 31 May 2027 | 2 articles | Viewed by 1367 | Submission Open
Keywords: natural products; immunomodulations; bioactive compounds; medicinal plants; therapeutic applications
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
New Advanced Research in Lung Injury and Fibrosis
edited by
submission deadline 31 May 2027 | 1 articles | Viewed by 684 | Submission Open
Keywords: pulmonary fibrosis; lung injury; idiopathic pulmonary fibrosis (IPF); fibroblast activation; therapeutic strategies; biomarker; epithelial-to-mesenchymal transition (EMT); oxidative stress; immune regulation; multi-omics research
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Research in Sarcopenia submission deadline 31 May 2027 | Viewed by 421 | Submission Open
Keywords: aging and muscle deterioration; secondary sarcopenia; metabolic diseases and sarcopenia; pathogen-induced muscle alterations; chronic disease-associated muscle loss; inflammatory sarcopenia mechanisms; sarcopenia biomarkers and diagnosis; therapeutic interventions; exercise and sarcopenia; muscle wasting syndromes; age-related frailty
(This special issue belongs to the Section Molecular and Translational Medicine)
Technologies and Applications of Genome Editing in Biomedicine
edited by Guanhua Xun
submission deadline 31 May 2027 | Viewed by 332 | Submission Open
Keywords: RNA therapeutics; mRNA vaccines; antisense oligonucleotides (ASOs); siRNA and miRNA therapeutics; nucleic acid modifications; chemical stability and delivery; gene regulation therapy; precision medicine; CRISPR/Cas systems; guide RNA (gRNA); genome editing
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Innovative Anticancer Agents: Design, Synthesis and Pharmacological Evaluation submission deadline 31 May 2027 | Viewed by 291 | Submission Open
Keywords: anticancer agents; drug design; pharmacological evaluation; structure–activity relationship; molecular docking; apoptosis; phytochemicals; oxidative stress; targeted therapy; natural products
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Horizons in Drug Discovery, Development, and Delivery
edited by
submission deadline 31 May 2027 | Viewed by 278 | Submission Open
Keywords: drug discovery; drug delivery; nanomedicine; computational pharmacology; targeted therapy; biopharmaceutical formulation; translational medicine; precision medicine; drug development pipeline; nanocarriers
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Advanced Molecular Diagnosis and Treatment of Biliary Cancer
edited by Jing Han Hong
submission deadline 31 May 2027 | Viewed by 255 | Submission Open
Keywords: biliary tract cancer; cholangiocarcinoma; epigenetics; rare cancers; molecular characterisation; precision medicine; drug development; molecular heterogeneity; precision oncology; therapy; biomarkers; diagnosis; molecular mechanisms
(This special issue belongs to the Section Cancer Biology and Oncology)
Gene Therapies in Ovarian Cancer
edited by
submission deadline 31 May 2027 | Viewed by 212 | Submission Open
Keywords: ovarian cancer; gene therapy; viral and non-viral vectors; RNA-based therapeutics; CRISPR/Cas genome editing; TP53/p53 restoration; tumor microenvironment; nanoparticle delivery systems; combination therapy; translational and clinical applications
(This special issue belongs to the Section Cancer Biology and Oncology)
Asthma: Pathogenesis, Pharmacological Treatments, Advances in Therapies
edited by Mohammad Irshad Reza and Premanand Balraj
submission deadline 31 May 2027 | Viewed by 74 | Submission Open
Keywords: asthma pathogenesis; airway inflammation; airway remodeling; airway hyperresponsiveness; pharmacological therapy; biologics; severe asthma; molecular targets; biomarkers; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Microglial Immunity in Neurological Diseases
edited by Chen Wang and
submission deadline 31 May 2027 | Viewed by 66 | Submission Open
Keywords: microglia; neuroinflammation; neurodegeneration; immune signaling; CNS homeostasis; disease‑associated microglia; neuroimmune interactions; therapeutic targeting of microglia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Heart Failure: Novel Strategies for Diagnosis and Treatment submission deadline 31 May 2027 | Viewed by 51 | Submission Open
Keywords: heart failure; precision medicine; biomarkers; multi-omics; cardiovascular imaging; artificial intelligence; digital health; hemodynamic monitoring; guideline-directed medical therapy; device-based therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Pathogenesis, Tumor Microenvironment and Emerging Therapeutic Targets in Solid Tumors
edited by
submission deadline 31 May 2027 | Viewed by 47 | Submission Open
Keywords: molecular pathogenesis; tumor microenvironment; therapeutic resistance; targeted therapy; cancer metabolism; cancer epigenetics; extracellular vesicles; multi-omics; precision oncology; solid tumors
(This special issue belongs to the Section Cancer Biology and Oncology)
Male Reproductive Health in the Modern World submission deadline 31 May 2027 | Viewed by 46 | Submission Open
Keywords: male fertility; modern lifestyle factors; environmental reproductive toxicology; emerging environmental exposures; testicular microenvironment
(This special issue belongs to the Section Molecular and Translational Medicine)
Targeting Genomic Instability in Cancer
edited by and Veronica Castro-Aceituno
submission deadline 31 May 2027 | Viewed by 36 | Submission Open
Keywords: DNA damage response (DDR); DNA replication stress; genomic instability; radiotherapy; chemotherapy; therapeutic resistance
(This special issue belongs to the Section Cancer Biology and Oncology)
Maternal–Fetal Immune Interactions: From Preconception to Pregnancy Outcomes
edited by Milan Lackovic
submission deadline 31 May 2027 | Viewed by 28 | Submission Open
Keywords: maternal–fetal immunology; placental dysfunction; pregnancy complications; fetal growth restriction; reproductive immunology
(This special issue belongs to the Section Immunology and Immunotherapy)
From Mechanisms to Precision Medicine in Diabetes
edited by Vincenzo Trischitta
submission deadline 31 May 2027 | Viewed by 3 | Submission Open
Keywords: diabetes mellitus; precision medicine; mechanisms of disease; β-cell dysfunction; insulin resistance; biomarkers; disease heterogeneity; personalized treatment; translational research; metabolic reprogramming
(This special issue belongs to the Section Endocrinology and Metabolism Research)
The Impact of Natural Products on Human Health and Diseases
edited by Hataichanok Pandith
submission deadline 31 May 2027 | Viewed by 3 | Submission Open
Keywords: natural products; human health; disease prevention; bioactive compounds; medicinal plants; biological activity; molecular mechanisms; therapeutic potential; drug discovery; disease treatment
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Neurodegeneration No More: Cutting-Edge Technologies and Therapies in the Evolution of Neurodegenerative Disease Management—3rd Edition
edited by Masaru Tanaka
submission deadline 31 May 2027 | Submission Open
Keywords: Alzheimer’s disease; frontotemporal lobar degeneration; Parkinson’s disease; aging decline; mild cognitive impairment; multiple sclerosis; stroke; acquired brain damage; altered cognitive processes; brain functional impairment; neurocognitive disorders; cognitive, behavioral, and functional disorders; acquired trauma; brain plasticity and connectivity; non-invasive brain stimulation; diagnosis and treatment; functional evidence of altered cognition and connectivity; blood-based biomarkers; disease heterogeneity; prognosis; protein aggregation; inflammation; oxidative stress; medicinal plants; phytocompounds
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Risk Factors and Molecular Mechanisms in Diabetes and Cardiovascular Complications
edited by
submission deadline 10 Jun 2027 | 3 articles | Viewed by 2099 | Submission Open
Keywords: diabetes; cardiovascular disease; atherosclerosis; ischemic heart disease; insulin resistance; risk factors; molecular mechanisms
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Inherited Retinal Diseases: From Pathomolecular Mechanisms to Therapeutic Strategies, 2nd Edition submission deadline 30 Jun 2027 | 2 articles | Viewed by 4882 | Submission Open
Keywords: blindness; gene and protein function; pathogenesis; personalized diagnosis; precision therapy; retina; retinal degeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Drug Discovery of Novel Anti-Inflammatory Compounds, Their Molecular Targets, and Translational Advancements
edited by Shomaila Mehmood
submission deadline 30 Jun 2027 | 1 articles | Viewed by 4523 | Submission Open
Keywords: natural products; drug discovery; anti-inflammatory; oxidative stress; nitrative stress; immunomodulation; molecular mechanisms; signaling pathways; inflammatory diseases; bioavailability; translational research
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Strategies for Anticancer in p53 Mutated Cancers
edited by and
submission deadline 30 Jun 2027 | 1 articles | Viewed by 2724 | Submission Open
Keywords: p53; p63; p73; tumor suppressor gene; microRNA; long non-coding RNA; protein degradation; heat shock proteins; mutation; oncology
(This special issue belongs to the Section Cancer Biology and Oncology)
Fibroblasts: Insights from Molecular and Pathophysiology Perspectives—2nd Edition
edited by and
submission deadline 30 Jun 2027 | 2 articles | Viewed by 1492 | Submission Open
Keywords: fibroblasts and myofibroblasts; fibrosis (organ and tissue fibrosis); tissue remodelling; extracellular matrix; cellular signalling; fibroblast differentiation; new in vitro models of fibrotic-related diseases
(This special issue belongs to the Section Cell Biology and Pathology)
Advancing Precision Radiation Oncology in Head and Neck Cancers
edited by
submission deadline 30 Jun 2027 | 1 articles | Viewed by 1277 | Submission Open
Keywords: precision radiation oncology; head and neck cancers; oncogenetics; genomic biomarkers; radiosensitivity; adaptive radiotherapy; artificial intelligence; immunotherapy integration; proton therapy; deescalation strategies
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Liquid Biopsy from Technological Innovation to Therapeutic Intervention—2nd Edition
edited by and
submission deadline 30 Jun 2027 | 1 articles | Viewed by 855 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Diagnostic Biomarkers and Novel Therapeutics Targets for Fragile X Syndrome, Autism Spectrum Disorders and Genetic Neurodevelopmental Diseases: Advances and Challenges, 2nd Edition
edited by Yolanda De Diego-Otero and Rocio Calvo-Medina
submission deadline 30 Jun 2027 | Viewed by 404 | Submission Open
Keywords: fragile X syndrome; autism spectrum disorders; neurodevelopmental disorders; developmental neuroscience; cognitive development
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biomedical Applications of Microfluidics
edited by
submission deadline 30 Jun 2027 | Viewed by 368 | Submission Open
Keywords: microfluidics; organ-on-a-chip; lab-on-a-chip; disease modeling; regenerative medicine; cancer immunotherapy; biosensors; mathematical modeling; AI/ML; realtime sensing
(This special issue belongs to the Section Biomedical Engineering and Materials)
Novel Insights into Depression Research: Neurobiology, Models, Biomarkers and Therapies submission deadline 30 Jun 2027 | Viewed by 326 | Submission Open
Keywords: depression; neurobiology; biomarkers; experimental models; antidepressant therapies; personalized medicine; treatment resistance; pharmacology; psychiatric disorders
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Mechanisms and Emerging Therapies in Human Skeletal Disorders
edited by Sudeep Gautam
submission deadline 30 Jun 2027 | Viewed by 289 | Submission Open
Keywords: skeletal disorders; genetic bone diseases; metabolic bone disease; rare skeletal dysplasias; extracellular matrix biology; CRISPR genome editing; genetically modified mouse models; gene therapy; AAV-based therapeutics; RNA therapeutics; musculoskeletal regeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Biomarkers, Artificial Intelligence, and Advanced Therapies for Sepsis—3rd Edition
edited by , Chih-Hao Shen, and
submission deadline 30 Jun 2027 | Viewed by 66 | Submission Open
Keywords: sepsis; molecular biomarkers; artificial intelligence; multi-omics; precision medicine; immune dysregulation; host-pathogen interactions; targeted therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research of Perinatal Complications
edited by
submission deadline 30 Jun 2027 | Viewed by 44 | Submission Open
Keywords: perinatal complications; mechanisms; biomarkers; multi-omics; machine learning; precision medicine; risk factors; maternal and offspring health impact; interventions
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Strategies and Innovations in Drug Delivery
edited by
submission deadline 30 Jun 2027 | Viewed by 7 | Submission Open
Keywords: drug delivery systems; drug delivery; nanomedicine; nanotechnology; nanoparticles; polymer-based delivery systems; biomaterials; targeted drug delivery; controlled drug release; sustained drug release; stimuli-responsive delivery; drug targeting; biologics delivery; pharmaceutical formulations; pharmacokinetics; precision medicine
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Spinal Muscular Atrophy in the Era of New Therapies: Changing Phenotypes and Clinical Challenges
edited by
submission deadline 30 Jun 2027 | Viewed by 6 | Submission Open
Keywords: spinal muscular atrophy; SMN1; SMN2; newborn screening; nusinersen; risdiplam; onasemnogene abeparvovec; scoliosis; osteoporosis; metabolic diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Medicinal Chemistry, Chemical Biology and Multi-Omics Approaches for Drug Discovery
edited by Qiuji Ye and
submission deadline 30 Jun 2027 | Viewed by 6 | Submission Open
Keywords: medicinal chemistry; drug discovery; chemical biology; natural products; multi-omics; network pharmacology; bioinformatics; analytical chemistry; molecular mechanisms
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Female Reproductive Biology: Insights from Clinical and Molecular Studies
edited by
submission deadline 31 Jul 2027 | Viewed by 375 | Submission Open
Keywords: female reproductive biology; ovarian physiology; folliculogenesis; endometrial receptivity; reproductive ageing; molecular mechanisms; reproductive endocrinology; infertility; assisted reproductive technologies
(This special issue belongs to the Section Molecular and Translational Medicine)
Selected Papers in the 4th International Electronic Conference on Biomedicines (ECB 2027) submission deadline 31 Dec 2027 | Viewed by 53 | Submission Open
Keywords: immunology; neuroscience; cardiology; translational medicine; nanomedicine; cancer; regenerative medicine; metabolic diseases; bone biology; AI in biomedicines
(This special issue belongs to the Section Molecular and Translational Medicine)
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