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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mechanism and Clinical Perspective: Pathogens of Infectious Respiratory Diseases

edited by

Nirupam Biswas

submission deadline 31 Jul 2026 | Viewed by 20 | Submission Open

Keywords: pathogenesis; respiratory diseases; sepsis; mechanism; clinical perspectives; host– pathogen interactions

(This special issue belongs to the Section Immunology and Immunotherapy)

Acute and Chronic Heart Failure: Pathophysiology and New Therapeutic Developments, 3rd Edition

edited by

Serafino Fazio

and Valentina Mercurio

submission deadline 31 Jul 2026 | Viewed by 19 | Submission Open

Keywords: heart failure with reduced ejection fraction; heart failure with preserved ejection fraction; pathophysiological novelties; treatment advances; pulmonary arterial hypertension; at-home follow-up of patients with heart failure

(This special issue belongs to the Section Molecular and Translational Medicine)

New Diagnostic and Therapeutic Approaches in Diabetic Microvascular Complications, 3rd Edition

edited by

Ana Maria Dascalu

and

Dragos Serban

submission deadline 31 Jul 2026 | Viewed by 17 | Submission Open

Keywords: diabetic retinopathy; diabetic foot ulcer; inflammatory biomarkers; microbiota; novel therapies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Advances in Infectious and Inflammatory Diseases

edited by

Sherein Salem

submission deadline 31 Jul 2026 | Viewed by 16 | Submission Open

Keywords: infectious diseases; inflammatory pathology; systemic and organ-specific pathology; diagnostic and comparative pathology; histopathology and tissue-based diagnosis; molecular and immunohistochemical diagnostics; host– pathogen interactions; emerging and re-emerging pathogens; clinical– pathological correlations

(This special issue belongs to the Section Molecular and Translational Medicine)

Glaucoma: The Mechanisms and Novel Therapeutic Approaches

edited by Samantha Sze Wan Shan

submission deadline 31 Jul 2026 | Viewed by 16 | Submission Open

Keywords: intraocular pressure; ocular hypertension; outflow facility; gene-editing; epigenetic modifications; small RNAs; translational studies; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

BK Polyomavirus: Immunopathology and Therapeutic Approaches

edited by

Baptiste Demey

and

Sandrine Castelain

submission deadline 31 Jul 2026 | Viewed by 15 | Submission Open

Keywords: virus– host interactions; antiviral agents; host-directed antivirals; BK polyomavirus; viral immune evasion; neutralizing antibodies; transplantation; biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

Macrophages and Immune Modulation in Cancer Therapy

edited by

Max Kam-Kwan Chan

submission deadline 31 Jul 2026 | Viewed by 14 | Submission Open

Keywords: tumor-associated macrophages; macrophage plasticity; macrophage reprogramming; immune modulation; macrophage-targeted therapies; macrophage– stromal interactions

(This special issue belongs to the Section Cancer Biology and Oncology)

State of the Art on Demyelinating Diseases in Latin America

edited by

Víctor M. Rivera

and Liliana Patrucco

submission deadline 31 Jul 2026 | Viewed by 14 | Submission Open

Keywords: demyelinating disorders; multiple sclerosis; neuromyelitis optica spectrum disorder; MOG antibody-associated disease; IgG-Aquarin-4 antibody; anti-MOG antibody; acute disseminated encephalomyeloitis; MRI; cerebrospinal fluid; steroids; disease modifying therapies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Osteoblast Differentiation in Skeletal Disease States

edited by

Kyeong-Min Kim

and

Won-gu Jang

submission deadline 31 Jul 2026 | Viewed by 13 | Submission Open

Keywords: osteoblast differentiation; bone remodeling; skeletal diseases; inflammation and bone metabolism; cellular stress pathways; mesenchymal stem cells

(This special issue belongs to the Section Cell Biology and Pathology)

Bridging Advanced Research and Clinical Applications: AI and Molecular Insights in Gynecologic Oncology

edited by

Mario Fordellone

and

Marco La Verde

submission deadline 31 Jul 2026 | Viewed by 13 | Submission Open

Keywords: gynecologic cancer biomarkers; AI-driven molecular analysis; machine learning models; ovarian cancer gene signatures; endometrial cancer profiling; cervical cancer prediction; multi-omics integration; prognostic and predictive algorithms; precision gynecologic oncology; translational bioinformatics

(This special issue belongs to the Section Cancer Biology and Oncology)

Connections Between Diabetes Mellitus, Other Metabolic and Endocrine Dysfunctions and Cardiovascular Pathologies—Third Edition

edited by Dragos Cozma, Cristina Tudoran and Claudiu Stoicescu

submission deadline 31 Jul 2026 | Viewed by 12 | Submission Open

Keywords: diabetes mellitus; insulin resistance; metabolic syndrome; obesity thyroid; dysfunction hormonal; alterations endothelial; dysfunction coronary; artery disease; hypertension peripheric; arterial disease

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Clinical Genetics and Genomics of Neurodegenerative Diseases

edited by

Justin Miller

and

Laura Ibanez

submission deadline 31 Jul 2026 | Viewed by 12 | Submission Open

Keywords: dementia; neurodegeneration; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; ALS; genetics; genomics; translational medicine; frontotemporal dementia; LATE; prion disease; neurocognitive impairment; GWAS; polygenic risk

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Epigenetic Regulation and Its Impact for Medicine (3rd Edition)

edited by

Marie Černá

submission deadline 31 Jul 2026 | Viewed by 8 | Submission Open

Keywords: gene expression; DNA methylation; histone modifications; non-coding RNAs; biomarkers

(This special issue belongs to the Section Molecular and Translational Medicine)

Bioinformatics Analysis of RNA for Human Health and Disease—2nd Edition

edited by

Jihwan Ha

submission deadline 31 Jul 2026 | Submission Open

Keywords: bioinformatics; computational biology; machine learning; multi-omics data analysis; biomarker detection; biomedical AI convergence; medical and public health informatics; RNA sequencing (RNA-Seq); functional genomics; RNA-protein interactions; experimental validation of biomarkers; RNA structural biology; transcriptome-wide association studies (TWAS); gene expression profiling; RNA modifications (e.g.; m6A; pseudouridylation); in vitro and in vivo RNA functional studies; single-cell RNA analysis; RNA therapeutics development

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Neuroinflammation: From Mechanisms to Therapeutic Approaches

edited by

Yuen Gao

submission deadline 31 Jul 2026 | Submission Open

Keywords: neuroinflammation; molecular mechanism; cell-free stem-cell-based therapy; anti-inflammation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Hepatotoxicity: From Pathology to Novel Therapeutic Approaches (2nd Edition)

edited by

Sanda Win

submission deadline 15 Aug 2026 | 2 articles | Viewed by 5750 | Submission Open

Keywords: cell death; reactive metabolites; oxidative stress; stress signaling; mitochondria; adaptive immunity; HLA associations; hepatotoxicity; drugs; liver injury; adverse drug reaction; drug-induced autoimmune hepatitis; idiosyncratic-drug-induced liver injury; bile acid; drug-induced cholestasis; hepatotoxins; steatosis; fibrosis

(This special issue belongs to the Section Molecular and Translational Medicine)

Multiple Sclerosis: Diagnosis and Treatment—3rd Edition

edited by

Víctor M. Rivera

submission deadline 31 Aug 2026 | 4 articles | Viewed by 10444 | Submission Open

Keywords: multiple sclerosis; pathogenesis; progressive MS; MRI; disease-modifying therapies; demyelinating disorders; cognitive dysfunction; intestinal microbiota

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Periodontal Disease and Periodontal Tissue Regeneration—Second Edition

edited by

Irina-Georgeta Sufaru

and

Sorina Mihaela Solomon

submission deadline 31 Aug 2026 | 4 articles | Viewed by 5268 | Submission Open

Keywords: periodontal diagnosis; periodontal immunology; periodontal microbiology; periodontal tissue regeneration; tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Molecular Mechanisms of Normal and Malignant Hematopoiesis: 2nd Edition

edited by

Myunggon Ko

submission deadline 31 Aug 2026 | Viewed by 391 | Submission Open

Keywords: hematopoietic stem cells; self-renewal; differentiation; hematological malignancies; molecular mechanisms; genetic factors; epigenetic factors; transcriptional regulation; HSC niche; targeted therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Mitochondrial Medicine and Nanomedicine

edited by

Agnieszka Pyrczak-Felczykowska

submission deadline 31 Aug 2026 | Viewed by 271 | Submission Open

Keywords: nanomedicine; nanoparticles; drug delivery; mitochondria; cancer; neurodegenerative disease; metabolism; targeted therapy; mitochondrial function; bioactive compounds

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Nanostructures in Medicine: State of the Art and Future Challenges

edited by

Agnieszka Maria Kołodziejczyk

and

Boleslaw Karwowski

submission deadline 31 Aug 2026 | Viewed by 56 | Submission Open

Keywords: nanostructures/particles; anticancer and theranostic nanostructures; synthesis methods; disease diagnosis; bioinformatics; DNA damage/repair; clinical trials; drug delivery systems; advanced biomedical applications

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Innovative Anticancer Agents: Design, Synthesis and Pharmacological Evaluation

edited by

Sreenivasan Sasidharan

submission deadline 31 Aug 2026 | Viewed by 44 | Submission Open

Keywords: anticancer agents; drug design; pharmacological evaluation; structure– activity relationship; molecular docking; apoptosis; phytochemicals; oxidative stress; targeted therapy; natural products

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Translational and Precision Medicine in Osteoarthritis, Bone Healing and Musculoskeletal Diseases

edited by

James Vun

Payal Ganguly

and Heather Elizabeth Owston

submission deadline 31 Aug 2026 | Viewed by 41 | Submission Open

Keywords: osteoarthritis; non-union; osteoporosis; fracture related infection; fragility; bone regeneration; mesenchymal stromal cells; tissue engineering; scaffolds; growth factors

(This special issue belongs to the Section Molecular and Translational Medicine)

Oncolytic Viruses and Combinatorial Immunotherapy for Cancer (2nd Edition)

edited by

Zong Sheng Guo

and

Michael H. Lehmann

submission deadline 31 Aug 2026 | Viewed by 13 | Submission Open

Keywords: oncolytic virus; antitumor immunity; cold tumor; tumor antigen; cancer vaccine; immunotherapy; combinatorial therapy; immune checkpoint blockade

(This special issue belongs to the Section Immunology and Immunotherapy)

Insights into Retinal Development, Disease, and Neuroprotection with Pharmacologic and Perioperative Considerations

edited by Siyuan Song

submission deadline 31 Aug 2026 | Submission Open

Keywords: retinal development; retinal degeneration; diabetic retinopathy; glaucoma/optic neuropathy; neuroprotection; neuroinflammation; microglia; single-cell/spatial omics; retinal organoids; anesthesia and analgesia

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Trends in 3D Printing Processes for Biomedical Field: Opportunities and Challenges (2nd Edition)

edited by

M. R. Mozafari

submission deadline 15 Sep 2026 | 1 articles | Viewed by 6159 | Submission Open

Keywords: 3D/4D bioprinting techniques; 3D bioprinting processes; 3D cellular microenvironment; bio-inks; hydrogels

(This special issue belongs to the Section Biomedical Engineering and Materials)

Feature Reviews in Biomaterials for Oral Diseases

edited by

Oliver Schierz

submission deadline 30 Sep 2026 | 3 articles | Viewed by 6509 | Submission Open

Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants

(This special issue belongs to the Section Biomedical Engineering and Materials)

Emerging Trends in Cardioimmunology: Pathomechanisms and Therapeutic Strategies

edited by

Gabriel Adzika

submission deadline 30 Sep 2026 | Viewed by 269 | Submission Open

Keywords: cardiovascular diseases; inflammation; auto-immunity; pathological remodeling; immunomodulation; treatment strategies

(This special issue belongs to the Section Immunology and Immunotherapy)

The Peripheral Nervous System: Morphology and Function

edited by Samanta Taurone

submission deadline 30 Sep 2026 | Viewed by 194 | Submission Open

Keywords: peripheral nerves; plexuses; dismetabolic neuropathies; inflammatory neuropathies; nerve trunk morphology; nerve trunk cells; nerve injury; neurophysiology; nerve repair; PNS regeneration

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Immunometabolism in Disease Development

edited by Aurora Garcia Tejedor and

Jose Moisés Laparra

submission deadline 30 Sep 2026 | Viewed by 78 | Submission Open

Keywords: immunometabolism; metabolic reprogramming; cancer immunometabolism; metabolic checkpoints; therapeutic targeting; chronic inflammation; signaling pathways; gut– liver– brain; bioenergetics

(This special issue belongs to the Section Immunology and Immunotherapy)

Computed Tomography Cardiac Imaging: Challenges, Current Status, and Advances

edited by Ammar Hoori

submission deadline 30 Sep 2026 | Viewed by 58 | Submission Open

Keywords: computed tomography; coronary CT angiography (CCTA); CT calcium scoring (CTCS); FFR-CT; CT perfusion imaging; quantitative imaging biomarkers; image reconstruction; artifact reduction; artificial intelligence; deep learning

(This special issue belongs to the Section Biomedical Engineering and Materials)

Decoding Metabolic Dysfunction: Multi-Omics Biomarkers and Their Modulation by Bioactives

edited by Bojlul Bahar

submission deadline 30 Sep 2026 | Submission Open

Keywords: multi-omics; metabolic dysfunction; nutraceuticals; biomarkers; metabolomics; nutrigenomics; epigenetics; chronic disease; precision nutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

Musculoskeletal Diseases: From Molecular Basis to Therapy—3rd Edition

edited by

Elisa Belluzzi

and

Assunta Pozzuoli

submission deadline 31 Oct 2026 | 7 articles | Viewed by 9568 | Submission Open

Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Phenotypes and Endotypes in Interstitial Lung Diseases—Second Edition

edited by

Francesco Amati

submission deadline 31 Oct 2026 | 2 articles | Viewed by 1266 | Submission Open

Keywords: interstitial lung diseases (ILDs); heterogeneity; pathogenesis; progressive pulmonary fibrosis (PPF); molecular biomarkers

(This special issue belongs to the Section Immunology and Immunotherapy)

From Gut to Vascular Health: The Role of Probiiotics, Polyphenols, and Diet in Neuroinflammation and Cardiovascular Dysfunction

edited by Maria Serra and

Roberta Macri

submission deadline 31 Oct 2026 | Viewed by 40 | Submission Open

Keywords: nutrition supplements; plant extract; polyphenols; oxidative stress; inflammation; neuroinflammation; microbiota; cardiometabolic dysfunction

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Respiratory Infections: New Diagnostic and Therapeutic Approaches

edited by Aleksandar Sovtic

submission deadline 31 Oct 2026 | Viewed by 9 | Submission Open

Keywords: pneumonia; lower respiratory infections; respiratory microbiota; cystic fibrosis; pneumococcal disease; bronchiolitis; pertussis; biofilm

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research on Genitourinary Cancer

edited by Jue Wang

submission deadline 30 Nov 2026 | 3 articles | Viewed by 9380 | Submission Open

Keywords: genitourinary (GU) cancer; prostate; bladder; kidney; and testicular cancer; diagnosis; treatment; pathogenesis; precision medicine; biomarker discovery; genomic profiling

(This special issue belongs to the Section Molecular and Translational Medicine)

Pediatric Tumors: Diagnosis, Pathogenesis, Treatment, and Outcome

edited by Hermann L. Müller

submission deadline 30 Nov 2026 | 5 articles | Viewed by 4911 | Submission Open

Keywords: pediatric oncology; leukemia; sarcoma; brain tumor; chemotherapy; irradiation; targeted therapy; sequelae

(This special issue belongs to the Section Cancer Biology and Oncology)

From Molecules to Minds: Translational Breakthroughs in Preclinical Psychiatry

edited by

Masaru Tanaka

Simone Battaglia

and

Sandra Barbalho

submission deadline 31 Dec 2026 | 1 articles | Viewed by 4048 | Submission Open

Keywords: depression; anxiety; bipolar disorder; post-traumatic stress disorder; mental disorders; epigenomics; psychiatric disorders/genetics; circadian rhythm; sex characteristics; mitochondrial dysfunction; neurotoxins; intergenerational transmission; cannabinoid receptor modulators; adolescent neuroplasticity; synaptic pruning; psychoimmunology; preclinical studies; translational medical research; neuroplasticity; neuromodulation; phytochemicals; plant extracts; transcranial magnetic stimulation

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathophysiology of Fatty Acid Metabolism

edited by

Nikolina Kolobarić

and

Ines Drenjančević

submission deadline 31 Dec 2026 | 2 articles | Viewed by 2494 | Submission Open

Keywords: fatty acids; signalling molecules; gene expression; metabolic disorders

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Optogenetic Tools for Probing Biology

edited by

Qunxiang Ong

submission deadline 31 Dec 2026 | Viewed by 212 | Submission Open

Keywords: optogenetics; signaling transduction; neuroscience; immunology; cancer signaling; synthetic biology; spatiotemporal resolution

(This special issue belongs to the Section Molecular and Translational Medicine)

Displaying special issue 751-800 on page 16 of 16.

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