Clinical Genetics and Genomics of Neurodegenerative Diseases
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: 31 July 2026 | Viewed by 933
Editors
2. Sanders-Brown Center on Aging, University of Kentucky, Lexington, KY 40536, USA
3. Division of Biomedical Informatics, Department of Internal Medicine, University of Kentucky, Lexington, KY 40536, USA
4. Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, KY 40536 USA
Interests: genetics; Alzheimer’s disease; neuroscience
Special Issues, Collections and Topics in MDPI journals
2. NeuroGenomics and Informatics Center, Washington University in Saint Louis School of Medicine, Saint Louis, MO 63110, USA
3. Department of Neurology, Washington University in Saint Louis School of Medicine, Saint Louis, MO 63110, USA
Interests: neurodegeneration; biomarkers; Alzheimer’s disease; Parkinson’s disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The prevalence of neurodegenerative disorders is rapidly increasing, and it is expected to continue to grow as the global population ages. Neurodegenerative disorders encompass various conditions, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, ALS, motor neuron disease, prion disease, dementia-type diseases (FTD, CTE, LBD, LATE, etc.), and many others that progressively affect memory, movement, thinking, and behavior. Recent advances in large-scale genomic studies have revealed some of the underlying molecular causes of these disorders, but more work is needed to translate these findings to the clinic. Moreover, the genes, proteins, protein modifications, etc., driving these associations and their implications for disease progression and potential therapeutic interventions remain largely unknown.
This Special Issue, entitled “Clinical Genetics and Genomics of Neurodegenerative Diseases”, is intended to provide a platform for a wide range of reviews, research articles, communications, and technical notes related to the genomics of neurodegenerative disorders. We encourage manuscripts to have a strong genomic component that may include, but is not limited to, machine learning of high-throughput data associated with Alzheimer’s disease and other dementias, genome-wide association studies, proteomic studies, functional studies for Alzheimer’s disease-related genes or variants or other neurodegenerative diseases, personalized genetics, gene expression analyses, clinical trials with a genetic component, rare variant analyses, and other bioinformatics analyses of Alzheimer’s disease using DNA or RNA sequencing data. We are especially interested in how genetics can influence therapeutic responses and better inform clinical practice, whether through earlier diagnoses and screening or patient-centered treatment plans. Please contact the Guest Editors with questions related to the scope of this Special Issue.
Dr. Justin Miller
Dr. Laura Ibanez
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- dementia
- neurodegeneration
- Alzheimer’s disease
- Parkinson’s disease
- Huntington’s disease
- ALS
- genetics
- genomics
- translational medicine
- frontotemporal dementia
- LATE
- prion disease
- neurocognitive impairment
- GWAS
- polygenic risk
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
