Optogenetic Tools for Probing Biology
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 31 December 2026 | Viewed by 216
Special Issue Editor
Interests: optogenetics; signaling transduction; protein structure; post-translational modifications; neuroscience; metabolic diseases; synthetic biology
Special Issue Information
Dear Colleagues,
This Special Issue, Optogenetic Tools for Probing Biology, aims to highlight the rapidly expanding role of optogenetics as a versatile and transformative platform for interrogating biological systems. By harnessing light to control molecular, cellular, and physiological processes with exceptional spatial and temporal precision, optogenetic approaches have become indispensable tools across the life sciences.
We invite contributions that present the development of innovative optogenetic tools, strategies, and conceptual frameworks, as well as their application to fundamental and translational biological questions. Topics of interest span, but are not limited to, traditional optogenetic tools, generative optogenetics, intracellular signaling, protein–protein interactions, organelle dynamics, metabolism, gene regulation, and cell–cell communication, with relevance to fields such as synthetic biology, neurobiology, immunology, developmental biology, cancer, and metabolic disease. Studies that integrate optogenetics with complementary methodologies—such as imaging, chemical biology, systems biology, or computational modeling—are particularly encouraged.
By bringing together methodological advances and diverse biological applications, this Special Issue seeks to foster cross-disciplinary dialog and inspire new ways of using optogenetic tools to dissect complex biological processes. Ultimately, our goal is to showcase how optogenetics can serve as a unifying and powerful approach to probing biology, yielding mechanistic insights that advance both fundamental understanding and future therapeutic innovation.
Dr. Qunxiang Ong
Guest Editor
Manuscript Submission Information
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Keywords
- optogenetics
- signaling transduction
- neuroscience
- immunology
- cancer signaling
- synthetic biology
- spatiotemporal resolution
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