The Role of Chemerin in Human Disease2nd Edition

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".

Deadline for manuscript submissions: 30 September 2024 | Viewed by 178

Special Issue Editor

Special Issue Information

Dear Colleagues,

This Special Issue, entitled “The Role of Chemerin in Human Disease”, will focus on the selection of recent research topics and up-to-date review articles focusing on the role of chemerin in disease.

Chemerin is a well-characterized adipokine which has multiple functions. Adipose tissue and serum levels are increased in the obese, and chemerin plays a significant role in adipogenesis and glucose homeostasis. The C-terminal processing of chemerin generates biologically active isoforms and, moreover, contributes to chemerin inactivation. Different chemerin isoforms have been identified, but their particular physiological functions remain mostly unknown. Chemerin isoform tissue distribution, signalling pathways, and biological activities require further investigation.

There is emerging evidence that chemerin is an important molecule in various cancers. Leukocyte recruitment via this chemoattractant mostly leads to the suppression of tumor growth, while chemerin-induced angiogenesis is one of its tumor-promoting activities. Chemerin has already been described as a major factor in various diseases, such as coronary artery disease, hypertension, Alzheimer´s disease, and chronic obstructive pulmonary disease.

With this Special Issue of Biomedicines, we aim to collect articles which clarify the pathophysiological role of chemerin in human diseases. Articles investigating chemerin’s role as a biomarker in human diseases are also welcome. Moreover, we invite authors to write review articles providing a comprehensive and critical overview of the current literature.

Prof. Dr. Christa Buechler
Guest Editor

Manuscript Submission Information

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Keywords

  • biomarker
  • chemotaxis
  • cardiovascular diseases
  • cancer
  • chemerin isoforms
  • CMKLR1
  • GPR1
  • CCRL2

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Published Papers

This special issue is now open for submission.
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