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Bioengineering publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cutting-Edge Applications of Machine and Deep Learning in Biomedical Signal and Image Processing

edited by

Pedro Miguel Rodrigues

, Bruno Bispo and Joaquim Celestino

submission deadline 28 Feb 2026 | 3 articles | Viewed by 7103 | Submission Open

Keywords: biosignal analysis; medical image analysis; machine learning; deep learning; wearable bio-technology

(This special issue belongs to the Section Biosignal Processing)

Deep Learning in Medical Applications: Challenges and Opportunities

edited by Richard Bayford,

Sikandar Ali

and

Ali Hussain

submission deadline 28 Feb 2026 | 2 articles | Viewed by 6665 | Submission Open

Keywords: deep learning; medical imaging; healthcare; artificial intelligence

(This special issue belongs to the Section Biosignal Processing)

Biomaterials and Technology for Oral and Dental Health

edited by

Gherlone Felice Enrico

and

Giulia Teté

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5780 | Submission Open

Keywords: biomaterials; odontoiatria; oral and dental health

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Progress in Craniofacial Regeneration

edited by

Chengfei Zhang

and

Zhaoming Wu

submission deadline 28 Feb 2026 | 3 articles | Viewed by 5623 | Submission Open

Keywords: craniofacial regeneration; regenerative medicine; tissue engineering; craniofacial stem cells; organoid; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Biomechanics and Mechanobiology in Cell and Tissue Engineering

edited by

Aaron Baker

submission deadline 28 Feb 2026 | 4 articles | Viewed by 5234 | Submission Open

Keywords: biomechanics; mechanobiology; tissue engineering; cell engineering; vascular; cardiovascular; neuroengineering; stem cells; cancer; osteoarthritis; bone

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Recent Progress in Stem Cells and Stem Cell-Derived Biotherapeutics for Regenerative Medicine Applications

edited by

Johnson Rajasingh

and Arghya Paul

submission deadline 28 Feb 2026 | 2 articles | Viewed by 5233 | Submission Open

Keywords: stem cells; extracellular vesicles; exosomes; regenerative medicine; induced pluripotent stem cells; disease model; mesenchymal stem cells

(This special issue belongs to the Section Regenerative Engineering)

Insights in Tissue Engineering: Novel Developments, Current Challenges, and Future Perspectives

edited by

Philippe Abdel-Sayed

submission deadline 28 Feb 2026 | 3 articles | Viewed by 4909 | Submission Open

Keywords: bioprinting; organ-on-chip; stem cells; vascularization; regeneration; tissue engineering; scaffold; biomaterials; organoids; ATMP

(This special issue belongs to the Section Regenerative Engineering)

Machine Learning and Artificial Intelligence in Pediatric Healthcare

edited by

Hammad Ashraf Ganatra

submission deadline 28 Feb 2026 | 3 articles | Viewed by 3318 | Submission Open

Keywords: artificial intelligence; machine learning; pediatrics; natural language processing; diagnostics

(This special issue belongs to the Section Biosignal Processing)

New Trends in Biomechanical Modeling in Musculoskeletal Disorders and Diseases

edited by

Philippe Gorce

submission deadline 28 Feb 2026 | 1 articles | Viewed by 2787 | Submission Open

Keywords: musculoskeletal disorders; musculoskeletal diseases; injury biomechanics; muscle biomechanics dynamic and kinematic modeling; gait and posture; muscle electromyography; motion analysis; postural control and balance; occupational health; occupational ergonomics; sport medicine; sport performance; quality of life

(This special issue belongs to the Section Biomechanics and Sports Medicine)

IoT Technology in Bioengineering Applications: Second Edition

edited by Mihaela Hnatiuc and Larbi Boubchir

submission deadline 28 Feb 2026 | 2 articles | Viewed by 2582 | Submission Open

Keywords: robotic device; signal processing; image processing; communication protocol; embedded system; smart sensors; cloud/FOG; predictive methods; monitoring; process optimization; diagnosis; implant; tele surgery; teleconsultation; telemonitoring

(This special issue belongs to the Section Biosignal Processing)

The Next Generation of Tissue Engineering

edited by Tetsuya Imamura

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1962 | Submission Open

Keywords: tissue engineering; mesenchymal stem cells; engineered cell sheets; biofabricated cell structures

(This special issue belongs to the Section Regenerative Engineering)

Transcranial Direct Current Stimulation: Bridging Bioengineering and Neuroscience for Brain Health

edited by

Josué Fernández-Carnero

and

Víctor Navarro López

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1543 | Submission Open

Keywords: transcranial direct current stimulation (tDCS); neuroplasticity; neuromodulation

(This special issue belongs to the Section Biosignal Processing)

Diagnostic Tools and Therapeutic Strategies for Hip Diseases

edited by Antonio Capone,

Giuseppe Marongiu

and

Lorenza Mattei

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1353 | Submission Open

Keywords: hip disease; coxarthrosis; arthritis; joint inflammatory disease; total hip arthroplasty; hip revision surgery; 3D printing; 3D modeling; advanced diagnostic imaging; tribology; finite element analysis

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

AI-Driven Approaches to Diseases Detection and Diagnosis

edited by Yannis Trakadis and

Antonio Brunetti

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1238 | Submission Open

Keywords: AI-driven diagnostics; disease detection; AI-driven treatment selection; precision medicine; +/− patient stratification; machine learning; deep learning; medical imaging; digital biomarkers; clinical decision support

(This special issue belongs to the Section Biosignal Processing)

Bioengineered Contact Lenses: Therapeutics, Biosensing, and Smart Interfaces

edited by

Ahmed Abass

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1197 | Submission Open

Keywords: contact lenses; vision correction; refractive error; smart contact lenses; drug delivery; biosensors; ocular physiology; corneal biomechanics; tear film; biocompatibility; biomedical engineering; responsive materials; wireless systems; myopia management and control; presbyopia; lens design; ocular surface; clinical applications; advanced manufacturing; digital health; mobile health apps

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advances in Robotic-Assisted Rehabilitation

edited by

Hongwu Wang

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1156 | Submission Open

Keywords: robotics-assisted rehabilitation; neurological rehabilitation robotics; wearable robotics; exoskeletons and assistive robotics; adaptive control in robotics; human– robot interaction; AI and machine learning in rehabilitation; translational studies in rehabilitation robotics; ethical considerations in rehabilitation robotics

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advanced 3D-Printed Biomaterials in Dentistry

edited by Andreas Zenthöfer and Ralf Erber

submission deadline 28 Feb 2026 | 1 articles | Viewed by 945 | Submission Open

Keywords: additive manufacturing; 3D printing; ceramics; polymer-based materials; bone substitutes

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advanced Restorative Dental Materials and Implant Technologies

edited by

Elena-Raluca Baciu

Alice Mirela Murariu

and

Gabriela Luminița Gelețu

submission deadline 28 Feb 2026 | 1 articles | Viewed by 866 | Submission Open

Keywords: biomaterials; restorative dentistry; dental implants; patient specific implants; nanotechnology; guided tissue regeneration; digital dentistry; minimally invasive techniques; 3D printing

(This special issue belongs to the Section Regenerative Engineering)

Advancements and Innovations in Photoacoustic Imaging: Pioneering Techniques and Clinical Applications in Biomedical Research

edited by

Praveen Kumar Panangattukara Prabhakaran

Taeho Kim

and

Dong-Kwon Lim

submission deadline 28 Feb 2026 | 1 articles | Viewed by 864 | Submission Open

Keywords: tomography; deep tissue imaging; photoacoustic imaging; contrast agents; probes; nanoparticles; clinical applications; multimode imaging

(This special issue belongs to the Section Biosignal Processing)

Artificial Intelligence in Dentistry: Innovations, Applications, and Future Perspectives, 2nd Edition

edited by

Hang Nga Mai

and

Tim Joda

submission deadline 28 Feb 2026 | 1 articles | Viewed by 761 | Submission Open

Keywords: artificial intelligence; big data in dentistry; explainable AI in dental diagnostics; blockchain in dental data security; natural language processing in dental records; robotics in dentistry; smart dental devices; AI in clinical decision support; automation in dentistry; AI-based diagnostic imaging; AI-supported treatment planning

(This special issue belongs to the Section Biosignal Processing)

Mechanobiology in Biomedical Engineering—2nd Edition

edited by Chun-Yuh Huang

submission deadline 28 Feb 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: mechanobiology; stem cells; tissue engineering; cancer; bone; articular cartilage; intervertebral disk; chondrocytes; tumor microenvironment; organ fibrosis; mechanotransduction; muscle; skin; liver; kidney; heart; blood vessel; brain; nerve; periodontal ligament; tooth; dental tissue; mechanical force; organoids

(This special issue belongs to the Section Biomechanics and Sports Medicine)

Neuroimaging Techniques and Applications in Neuroscience

edited by

Md Nasir Uddin

submission deadline 28 Feb 2026 | 1 articles | Viewed by 716 | Submission Open

Keywords: neuroimaging; brain; MRI; MR angiography; fMRI; PET; machine learning; artificial intelligence; neurological disorders

(This special issue belongs to the Section Biosignal Processing)

Engineering with Nature: Bioengineering Innovations for the Environment and Nature-Based Solutions

edited by

Kristian L. Dubrawski

submission deadline 28 Feb 2026 | 1 articles | Viewed by 472 | Submission Open

Keywords: nature-based solutions; bioengineering; environmental sustainability; bioremediation; ecological engineering

(This special issue belongs to the Section Biochemical Engineering)

Artificial Intelligence (AI) in Bioengineering

edited by William C. Tang and Nathan Leroux

submission deadline 28 Feb 2026 | Viewed by 412 | Submission Open

Keywords: artificial intelligence; bioengineering; computational models; intelligent algorithms; biologically inspired systems; healthcare; diagnostics; personalized medicine; medical imaging analysis; biomedical signal processing; drug discovery and development; smart prosthetics and assistive technologies; clinical decision-making

(This special issue belongs to the Section Biosignal Processing)

Advancing Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) Through Computer-Aided Drug Design

edited by

Chin-Hung Lai

and

Suraj Narayan Mali

submission deadline 28 Feb 2026 | Viewed by 396 | Submission Open

Keywords: molecular docking; molecular dynamics; QSAR; AI; NSAIDs

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

New Sights of Image Processing and Digital Models in Biomedicine

edited by Seyed Jalalddelin Mousavirad and

Diego Oliva

submission deadline 28 Feb 2026 | Viewed by 394 | Submission Open

Keywords: image processing and computer vision; deep learning; artificial intelligence; biomedicine

(This special issue belongs to the Section Biosignal Processing)

Cognitive Decline and Its Transversality: Potential Mechanisms and Modulators of Disease

edited by

Cinzia Coppola

and

Elisabetta Signoriello

submission deadline 28 Feb 2026 | Viewed by 389 | Submission Open

Keywords: cognitive decline; Alzheimer’ s disease; fronto-temporal lobar degeneration; Lewy body disease; multiple sclerosis; protein misfolding; amyloid; tauopathy; neuroinflammation; microglia; astroglia; synaptopathy; CSF biomarkers; plasmatic biomarkers; micro-RNA or miRNA; long noncoding RNA or lncRNA; heart– brain axis; gut– brain axis; cerebrovascular disease; hippocampal atrophy; structural and functional neuroimaging

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Advancements in Human–Machine Interaction and Robotics: From Biomechanics to Cognitive Neuroscience

edited by Jiejunyi Liang

submission deadline 28 Feb 2026 | Viewed by 369 | Submission Open

Keywords: human-machine interaction; robotics; biomechanics; cognitive neuroscience; anthropomorphic robotic systems

New Sight of Deep Learning in Bioengineering: Updates and Future Directions (2nd Edition)

edited by

Tao Zhang

submission deadline 28 Feb 2026 | Viewed by 297 | Submission Open

Keywords: deep learning; biomedicine; robotics and biomechanics; biomedical imaging; biosignal processing

(This special issue belongs to the Section Biosignal Processing)

Wearable Technologies and Health Informatics: Advancements in Bioengineering

edited by

Iqram Hussain

and

Jahowa Islam

submission deadline 28 Feb 2026 | Viewed by 261 | Submission Open

Keywords: wearable sensors; health monitoring; large language model; electronic health record; flexible sensors; sensors; artificial intelligence; smart healthcare; data privacy; machine learning; sensor applications; energy efficiency; health diagnostics; wearable signal processing (EEG; ECG; EMG; PPG; and IMU); internet of things (IoT); activity recognition; biomedical techniques; sleep medicine; smart grid; data science; smart surveillance

(This special issue belongs to the Section Biosignal Processing)

Advances in Soft Matter for Healthcare Applications

edited by

Ahmed Abass

submission deadline 28 Feb 2026 | Viewed by 179 | Submission Open

Keywords: soft matter; healthcare applications; hydrogels; drug delivery systems; flexible electronics; tissue engineering; soft robotics; bio-inspired materials; responsive materials; wearable sensors; biomedical devices; smart materials; thermally active materials; hot water bottles; pain management; biocompatible materials; clinical translation

Wearable Sensors and Robotic-Assisted Technologies for Activity Assistance and Gait Rehabilitation

edited by

Chun-Ta Chen

and Xiaoling Hu

submission deadline 28 Feb 2026 | Viewed by 154 | Submission Open

Keywords: wearable sensors; robotic-assisted technology; activity assistance; gait rehabilitation; balance; movement impairment; exoskeleton robot

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Approaches in Lung Injury and Repair

edited by

Antonio Matías Esquìnas

submission deadline 28 Feb 2026 | Viewed by 144 | Submission Open

Keywords: bioengineering; lung injury; repair mechanisms; stem cell therapy; biomaterials

(This special issue belongs to the Section Regenerative Engineering)

Biofabrication of Biologically Realistic Constructs: Needs, Challenges, and Opportunities

edited by Nicanor Ilie Moldovan

submission deadline 28 Feb 2026 | Viewed by 131 | Submission Open

Keywords: biofabrication; biological realism; bioprinting; cell– biomaterial interaction; tissue engineering; hybrid constructs; clinical translation; in vitro models

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Multiscale Mechanics of Biomaterials

edited by Pengfei Dong,

Linxia Gu

and Yi Hua

submission deadline 28 Feb 2026 | Viewed by 123 | Submission Open

Keywords: multiscale mechanics; atomic force microscopy; machine learning; biomaterials; finite element method

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Multimodal AI‑Assisted Bioprinting: From Material Selection to Automated Fabrication

edited by Ewa Stodolak-Zych,

Ryszard Tadeusiewicz

and Kamila Rawojć

submission deadline 28 Feb 2026 | Viewed by 117 | Submission Open

Keywords: 3D bioprinting; artificial intelligence; machine learning; bioink design; tissue engineering; multimodal data; closed-loop fabrication; automated manufacturing

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advanced Technologies for Orthopedic Repair and Regeneration

edited by Adriano Braile,

Mariantonia Braile

and Giuseppe Toro

submission deadline 28 Feb 2026 | Viewed by 117 | Submission Open

Keywords: orthopedic regeneration; 3D printing; bioactive materials; mesenchymal stem cells; smart biomaterials; tissue engineering; predictive modeling; immunoengineering; antimicrobial strategies; personalized implants

(This special issue belongs to the Section Regenerative Engineering)

Stem Cell Culture and Development of Tissue Engineered Models

edited by

Giuseppe Pettinato

submission deadline 28 Feb 2026 | Viewed by 115 | Submission Open

Keywords: stem cell culture; tissue engineering; organoids; biomaterials; 3D cell culture; regenerative medicine; disease modeling; organ-on-a-chip

(This special issue belongs to the Section Regenerative Engineering)

Bioinformatics for Cardiovascular Disease

edited by João P. Monteiro and Quanyi Zhao

submission deadline 28 Feb 2026 | Viewed by 107 | Submission Open

Keywords: bioinformatics; cardiovascular disease; single-cell RNA-seq; single-cell ATAC-seq; spatial profiling; genomics; machine learning; multi-omics integration; systems biology; cardiac modeling; precision medicine; big data; translational bioinformatics

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Big Data and Artificial Intelligence in Trauma Outcome Prediction

edited by Peter Fu Ming Hu, Shiming Yang and William Teeter

submission deadline 28 Feb 2026 | Viewed by 104 | Submission Open

Keywords: trauma triage; emergency medicine; clinical decision support; outcome prediction; precision medicine; artificial intelligence; natural language processing

(This special issue belongs to the Section Biosignal Processing)

Polymeric Biomaterials for Drug Delivery

edited by

Pere Dosta Pons

submission deadline 28 Feb 2026 | Viewed by 78 | Submission Open

Keywords: biomaterials; polymeric nanoparticles; stimuli-responsive systems; biodegradable polymers; drug delivery; gene therapy; targeted delivery; controlled release

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

From 3D/4D Printing to Biofunctional Surfaces and Smart Implant Systems

edited by

Yuhe Yang

submission deadline 28 Feb 2026 | Viewed by 73 | Submission Open

Keywords: 3D/4D printing; biofunctional surfaces; smart implants; additive manufacturing in biomedicine

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Advances in Novel Remineralizing Materials: Innovations for Sustainable Oral and Biomedical Applications

edited by Robert Hill

submission deadline 28 Feb 2026 | Viewed by 62 | Submission Open

Keywords: dental materials; remineralization; bioactive glass; glass ionomer cements; calcium phosphate cements; nanotechnology; adhesion; sustainable dentistry; clinical performance; biomedical engineering

(This special issue belongs to the Section Nanobiotechnology and Biofabrication)

Machine Learning in Ultrasound Imaging

edited by Laura Brattain, Vivek Singh and Md Mostafa Kamal Sarker

submission deadline 15 Mar 2026 | Viewed by 311 | Submission Open

Keywords: computer-aided diagnosis; medical image analysis; image segmentation; procedural guidance; clinical decision support; elastography; contrast-enhanced ultrasound; point-of-care ultrasound (POCUS); multimodal imaging

(This special issue belongs to the Section Biosignal Processing)

MRI and Its Applications

edited by

Dongrong Xu

Ravi Bansal

and

Zhiyong Zhao

submission deadline 20 Mar 2026 | Viewed by 158 | Submission Open

Keywords: MRI; multiparametric MRI; cancer Imaging; tumor characterization; therapy monitoring; whole-body MRI; pediatric MRI; oncologic imaging; clinical MRI

(This special issue belongs to the Section Biosignal Processing)

Bioengineering Strategies for Ophthalmic Diseases

edited by

Jae Yong Kim

submission deadline 31 Mar 2026 | 5 articles | Viewed by 9633 | Submission Open

Keywords: ophthalmic diseases; imaging technology; artificial intelligence; retinal regeneration; corneal implants; drug delivery

(This special issue belongs to the Section Biomedical Engineering and Biomaterials)

Applications of Computational Modeling in Biomedical Image and Signal Processing—2nd Edition

edited by Xuxin Chen and

Bin Zheng

submission deadline 31 Mar 2026 | 4 articles | Viewed by 8006 | Submission Open

Keywords: computational modeling; quantitative disease markers; medical image processing; image segmentation; biosignal testing; biosignal processes; feature selection; deep learning; computer-aided diagnosis; data standardization; synthetic data generation

(This special issue belongs to the Section Biosignal Processing)

Development of Bioelectrochemical Systems for Environmental Engineering

edited by

Shiue-Lin Li

submission deadline 31 Mar 2026 | 3 articles | Viewed by 7238 | Submission Open

Keywords: bioelectrochemical systems; microbial fuel cells; bioelectrosynthesis; high-added value chemicals; environmental engineering

(This special issue belongs to the Section Biochemical Engineering)

Innovative Approaches: Harnessing Virtual Reality for Assessment and Rehabilitation in Stroke and Aging-Related Disorders

edited by Gauthier Everard and

Charles Sebiyo Batcho

submission deadline 31 Mar 2026 | 6 articles | Viewed by 7127 | Submission Open

Keywords: virtual reality; assessment; rehabilitation; stroke; neurorehabilitation; older adults; kinematics; cognition

(This special issue belongs to the Section Biosignal Processing)

Recent Advances in Genomics Research

edited by Chien-Wei (Masaki) Lin

submission deadline 31 Mar 2026 | 3 articles | Viewed by 4748 | Submission Open

Keywords: genomics data analysis; NGS; AI; machine learning; multi-omics integration; single-cell sequencing; precision medicine

(This special issue belongs to the Section Cellular and Molecular Bioengineering)

Displaying special issue 151-200 on page 4 of 8.

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