Technologies for the Regeneration of Bone Tissue
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".
Deadline for manuscript submissions: 31 January 2026 | Viewed by 31
Special Issue Editors
Interests: stem cells; biomaterials; tissue engineering; regenerative medicine
Interests: biomaterials; biopolymers; tissue engineering; hydrogels
Special Issues, Collections and Topics in MDPI journals
Interests: biomaterials; tissue engineering; vascularization; orthopaedic applications; medical devices; biophysical stimulus; physico-chemical modification
Interests: scaffolds; bioceramics; hydroxyapatite; bone tissue engineering; bone cells; mesenchymal stem cells
Special Issue Information
Dear Colleagues,
Bone is a connective tissue that provides structural integrity to the human body, supports movement, and protects vital organs. Orthopaedic tissue engineering (OTE) uses a combination of cells, chemical and mechanical cues, and biomaterials to address clinical challenges such as non-union fractures; spinal fusion; and extensive bone defects due to trauma, diseases, or surgery.
Novel bioceramics, biopolymers, hydrogels, and composites have been developed and fabricated into complex orthopaedic scaffolds using a variety of techniques, including 3D bioprinting and cryogelation.
Over the years, numerous differentiation protocols for cell types such as MSCs and iPSCs have been investigated. These protocols often combine the use of growth factors and bioreactors.
To create functional bone tissue and enhance the success of its clinical outcomes, forming new vasculature and controlling the body’s immune response are of great importance. Furthermore, in situ tissue repair will aid in promoting personalised tissue regeneration strategies.
We welcome contributions to this Special Issue focusing on, but not limited to, the following:
- Biomaterials and scaffolds for orthopaedic tissue regeneration;
- Stem cells and cell therapy strategies;
- Guided bone regeneration;
- Angiogenesis for orthopaedic tissue regeneration;
- Immunomodulation for bone regeneration;
- Osseointegration;
- Mechanical and chemical cues promoting bone regeneration.
Dr. Yvonne Reinwald
Prof. Dr. Ying Yang
Guest Editors
Dr. Ruchi Mishra Tiwari
Dr. Yanny Marliana Baba Ismail
Guest Editor Assistants
Manuscript Submission Information
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Keywords
- bone tissue
- regenerative medicine
- immunomodulation
- angiogenesis
- growth factors
- mechanical stimulation
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