Technologies for the Regeneration of Bone Tissue

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 31

Special Issue Editors


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Guest Editor
School of Science and Technology, Department of Engineering, Nottingham Trent University, Nottingham NG11 8NS, UK
Interests: stem cells; biomaterials; tissue engineering; regenerative medicine

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Guest Editor
School of Life Science, Keele University, Staffordshire ST5 5BG, UK
Interests: biomaterials; biopolymers; tissue engineering; hydrogels
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Guest Editor Assistant
Symbiosis Centre for Stem Cell Research (SCSCR), Symbiosis International (Deemed University), Gram Lavale, Pune 412115, India
Interests: biomaterials; tissue engineering; vascularization; orthopaedic applications; medical devices; biophysical stimulus; physico-chemical modification

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Guest Editor Assistant
Biomaterials Niche Group, School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Engineering Campus, Nibong Tebal 14300, Penang, Malaysia
Interests: scaffolds; bioceramics; hydroxyapatite; bone tissue engineering; bone cells; mesenchymal stem cells

Special Issue Information

Dear Colleagues,

Bone is a connective tissue that provides structural integrity to the human body, supports movement, and protects vital organs. Orthopaedic tissue engineering (OTE) uses a combination of cells, chemical and mechanical cues, and biomaterials to address clinical challenges such as non-union fractures; spinal fusion; and extensive bone defects due to trauma, diseases, or surgery.

Novel bioceramics, biopolymers, hydrogels, and composites have been developed and fabricated into complex orthopaedic scaffolds using a variety of techniques, including 3D bioprinting and cryogelation.

Over the years, numerous differentiation protocols for cell types such as MSCs and iPSCs have been investigated. These protocols often combine the use of growth factors and bioreactors.

To create functional bone tissue and enhance the success of its clinical outcomes, forming new vasculature and controlling the body’s immune response are of great importance. Furthermore, in situ tissue repair will aid in promoting personalised tissue regeneration strategies.

We welcome contributions to this Special Issue focusing on, but not limited to, the following:

  1. Biomaterials and scaffolds for orthopaedic tissue regeneration;
  2. Stem cells and cell therapy strategies;
  3. Guided bone regeneration;
  4. Angiogenesis for orthopaedic tissue regeneration;
  5. Immunomodulation for bone regeneration;
  6. Osseointegration;
  7. Mechanical and chemical cues promoting bone regeneration.

Dr. Yvonne Reinwald
Prof. Dr. Ying Yang
Guest Editors

Dr. Ruchi Mishra Tiwari
Dr. Yanny Marliana Baba Ismail
Guest Editor Assistants

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • bone tissue
  • regenerative medicine
  • immunomodulation
  • angiogenesis
  • growth factors
  • mechanical stimulation

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Published Papers

This special issue is now open for submission.
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