Skip to Content
You are currently on the new version of our website. Access the old version .

International Journal of Translational Medicine, Volume 6, Issue 4

2026 December - 11 articles

  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (11)

  • Article
  • Open Access
44 Views
18 Pages

Background/Objectives: Glucose-lowering treatment can change insulin resistance indices without demonstrating improved insulin sensitivity. We described these changes during sodium–glucose cotransporter-2 (SGLT2) inhibitor therapy in routine ca...

  • Hypothesis
  • Open Access
17 Views
9 Pages

Late distant recurrence in estrogen receptor-positive (ER+) breast cancer raises the question of how disseminated tumor cells resume proliferation years after primary tumor resection. We propose two coupled processes: endocrine–immune condition...

  • Review
  • Open Access
205 Views
27 Pages

Background/Objectives: Polycystic ovary syndrome (PCOS), renamed polyendocrine metabolic ovarian syndrome (PMOS) in 2026, is a heterogeneous endocrine–metabolic disorder. Asparagus racemosus (Shatavari) is widely used for women’s reproduc...

(This article belongs to the Special Issue Drug Repurposing as a Synergistic Therapeutic Strategy for the Treatment of Various Diseases)
  • Article
  • Open Access
164 Views
13 Pages

Background: Large language models (LLMs) can generate clinically relevant information, but safety-related performance in systemic lupus erythematosus (SLE) remains insufficiently characterised. We compared GPT-5.5 Instant (ChatGPT), Claude Sonnet 4.6...

  • Review
  • Open Access
197 Views
21 Pages

Targeting Ferroptosis Pathways to Enhance Therapeutic Outcomes in Acute Myeloid Leukemia: A Systematic Review

  • Foteini-Maria Manouka,
  • Efthymia Papaioannou,
  • Marios-Lampros Theodorou Anagnostou,
  • Efthymios Giraleas and
  • Elisavet Georgiou

Background: Acute myeloid leukemia (AML) is an aggressive hematologic malignancy in which relapse and treatment resistance remain major clinical challenges. Ferroptosis, an iron-dependent form of regulated cell death driven by lipid peroxidation, has...

  • Review
  • Open Access
347 Views
26 Pages

Healthspan, the period of life free from major chronic disease and disability, is a central geroscience outcome, yet its prediction remains difficult due to its multidimensional and heterogeneous nature. In this review, we synthesize advances in arti...

  • Article
  • Open Access
294 Views
24 Pages

Pooled Follicular-Fluid Melatonin Under Standardized Supplementation in IVF-ICSI Cycles: Associations with Clinical Ovarian Response Phenotypes and Exploratory Embryological Outcomes: A Prospective Observational Study

  • Seval Tasdemir,
  • Muhammet Volkan Bulbul,
  • Betul Kalay,
  • Masite Sehadet Senol and ,
  • Safak Tavukcuoglu,
  • Fevzi Akcil,
  • Secil Nazife Parlak,
  • Suat Utku Keskin,
  • Turkan Yigitbasi and
  • Ege Can Serefoglu
  • + 5 authors+ 0 author

Background: Melatonin concentrations in follicular fluid exceed serum levels, suggesting local ovarian accumulation and a potential role in the follicular microenvironment. Previous studies reporting associations between intrafollicular melatonin and...

  • Article
  • Open Access
465 Views
15 Pages

Background/Objectives: Low-dose phthalate exposure acts as an adjuvant for immunoglobulin production and exacerbates atopic dermatitis (AD)-like lesions; however, research on orally administered di-(2-ethylhexyl) phthalate (DEHP)-mediated AD aggravat...

XFacebookLinkedIn
Int. J. Transl. Med. - ISSN 2673-8937