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Organics, Volume 5, Issue 4

December 2024 - 17 articles

Cover Story: l-(+)-Furanomycin, a crucial substrate for isoleucyl aminoacyl-tRNA synthetase, replaces isoleucine during protein translation and exhibits antibacterial properties in vitro. Various synthetic approaches have been developed to produce l-(+)-Furanomycin and its analogs. This review focuses on total synthesis strategies and the biological significance of Furanomycin, a distinctive antibacterial agent with a non-proteinogenic amino acid core. It covers its isolation and diverse synthetic methodologies, including those using chiral substrates like carbohydrates and amino acids and alternative approaches with achiral starting materials like furans and cyclopentadiene. Methods relying on amino acids are particularly appealing, involving only six to seven steps for a swift and flexible process to access Furanomycin and its analogs. View this paper
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Articles (17)

  • Article
  • Open Access
2 Citations
1,939 Views
14 Pages

22 December 2024

Various organic compounds susceptible to anodic polymerization were selected to study the effects of two solvents: acetic acid and ethyl acetate. Phenol and most of its derivatives, as well as resorcinol and 3,5-dihydroxybenzoic acid, exhibited typic...

  • Review
  • Open Access
9 Citations
4,105 Views
30 Pages

Conducting Polymers in Solar Cells: Insights, Innovations, and Challenges

  • Aliya Yelshibay,
  • Sherif Dei Bukari,
  • Bakhytzhan Baptayev and
  • Mannix P. Balanay

20 December 2024

The pursuit of sustainable energy sources has led to significant advances in solar cell technology, with conducting polymers (CPs) emerging as key innovations. This review examines how CPs improve the performance and versatility of three important ty...

  • Article
  • Open Access
1,361 Views
17 Pages

Unexpected Products of Salicylidene-Aminoguanidine Reactions with Metal Ions—Synthesis and Structural Aspects

  • Mirjana M. Radanović,
  • Ljiljana S. Vojinović-Ješić,
  • Niko S. Radulović,
  • Vidak N. Raičević,
  • Vukadin M. Leovac and
  • Marko V. Rodić

11 December 2024

Due to the promising characteristics of aminoguanidine Schiff bases, ongoing research focuses on synthesizing and characterizing different compounds of this class to establish structure–property relationships. However, the pronounced alkalinity...

  • Article
  • Open Access
1 Citations
2,402 Views
9 Pages

9 December 2024

We developed a selective technique to rapidly measure free chlorine, which is the sum of elemental chlorine (Cl2), hypochlorous acid (HOCl), and hypochlorite (OCl−) in water samples via an electrophilic aromatic substitution reaction hyphenated...

  • Article
  • Open Access
1,993 Views
16 Pages

9 December 2024

The synthesis of indole phytoalexin-like analogs related to alkyl (((1-(4-substitutedphenyl)-3-oxo-3-phenylpropyl)thio)carbonothioyl)-ʟ-tryptophanate 1a–d and the evaluation of their antifungal activity against the phytopathogen Fusarium o...

  • Review
  • Open Access
9 Citations
7,143 Views
23 Pages

5 December 2024

Pyrazole and tetrazole are among the most important heterocyclic members of the azole family. Over the past decade, these N-heterocycles and their derivatives have demonstrated specific properties that give them potent applications in several fields...

  • Article
  • Open Access
2 Citations
1,520 Views
14 Pages

28 November 2024

A simple approach was developed to efficiently graft diethylene triamine onto polystyrene waste using succinic anhydride as a tracer to remove nitrate anions from aqueous solutions. Infrared spectroscopic data showed characteristic signs at 3395 cm&m...

  • Review
  • Open Access
36 Citations
8,046 Views
41 Pages

Advances in Organic Materials for Next-Generation Optoelectronics: Potential and Challenges

  • Ghazi Aman Nowsherwan,
  • Qasim Ali,
  • Umar Farooq Ali,
  • Muhammad Ahmad,
  • Mohsin Khan and
  • Syed Sajjad Hussain

11 November 2024

This review provides a comprehensive overview of recent advancements in the synthesis, properties, and applications of organic materials in the optoelectronics sector. The study emphasizes the critical role of organic materials in the development of...

  • Article
  • Open Access
1 Citations
3,220 Views
13 Pages

7 November 2024

In this study, we developed an efficient strategy for constructing thieno[3,2-b]thiophene molecules from 3-nitrothiophenes, containing carbonyl fragments at the C-2 and C-5 atoms, by nucleophilic aromatic substitution of the nitro group in these subs...

  • Article
  • Open Access
1,580 Views
14 Pages

1,5-Acrylodan: A Fluorescent Bioconjugate Sensor of Protic Environments

  • Jake Morrin,
  • Matthew Petitt and
  • Christopher Abelt

7 November 2024

1,5-Acrylodan (1-(5-(dimethylamino)naphthalen-1-yl)prop-2-en-1-one) is prepared in six steps from 1-nitronaphthalene and 19% overall yield. The last three steps involve an aryllithium-directed nucleophilic addition, catalytic Kulinkovich cyclopropana...

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Organics - ISSN 2673-401X