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Tropical Medicine and Infectious Disease, Volume 5, Issue 1

March 2020 - 47 articles

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Articles (47)

  • Article
  • Open Access
13 Citations
4,644 Views
10 Pages

Can the High Sensitivity of Xpert MTB/RIF Ultra Be Harnessed to Save Cartridge Costs? Results from a Pooled Sputum Evaluation in Cambodia

  • Monyrath Chry,
  • Marina Smelyanskaya,
  • Mom Ky,
  • Andrew J Codlin,
  • Danielle Cazabon,
  • Mao Tan Eang and
  • Jacob Creswell

Despite the World Health Organization recommending the use of rapid molecular tests for diagnosing tuberculosis (TB), uptake has been limited, partially due to high cartridge costs. Other infectious disease programs pool specimens to save on diagnost...

  • Article
  • Open Access
14 Citations
6,205 Views
13 Pages

An Innovative Public–Private Mix Model for Improving Tuberculosis Care in Vietnam: How Well Are We Doing?

  • Thuong Do Thu,
  • Ajay M. V. Kumar,
  • Gomathi Ramaswamy,
  • Thurain Htun,
  • Hoi Le Van,
  • Luan Nguyen Quang Vo,
  • Thuy Thi Thu Dong,
  • Andrew Codlin,
  • Rachel Forse and
  • Jacob Crewsell
  • + 5 authors

To improve tuberculosis (TB) care among individuals attending a private tertiary care hospital in Vietnam, an innovative private sector engagement model was implemented from June to December 2018. This included: (i) Active facility-based screening of...

  • Brief Report
  • Open Access
5 Citations
4,440 Views
6 Pages

First Draft Genome of the Trypanosomatid Herpetomonas muscarum ingenoplastis through MinION Oxford Nanopore Technology and Illumina Sequencing

  • Claudia M. d’Avila-Levy,
  • Bertrand Bearzatto,
  • Jérôme Ambroise,
  • Raphaël Helaers,
  • Anzhelika Butenko,
  • Vyacheslav Yurchenko,
  • Karina A. Morelli,
  • Helena L. C. Santos,
  • Pascal Brouillard and
  • Philippe Grellier
  • + 2 authors

Here, we present first draft genome sequence of the trypanosomatid Herpetomonas muscarum ingenoplastis. This parasite was isolated repeatedly in the black blowfly, Phormia regina, and it forms a phylogenetically distinct clade in the Trypanosomatidae...

  • Article
  • Open Access
10 Citations
4,573 Views
10 Pages

Haemoparasitic Infections in Cattle from a Trypanosoma brucei Rhodesiense Sleeping Sickness Endemic District of Eastern Uganda

  • Enock Matovu,
  • Claire Mack Mugasa,
  • Peter Waiswa,
  • Annah Kitibwa,
  • Alex Boobo and
  • Joseph Mathu Ndung’u

We carried out a baseline survey of cattle in Kaberamaido district, in the context of controlling the domestic animal reservoir of Trypanosoma brucei rhodesiense human African trypanosomiasis (rHAT) towards elimination. Cattle blood was subjected to...

  • Commentary
  • Open Access
39 Citations
14,029 Views
8 Pages

The objectives of this paper are to provide a review of the author’s personal experiences working in culturally diverse environments and to emphasize the importance of recognizing the social determinants of health. While some determinants of he...

  • Article
  • Open Access
8 Citations
4,325 Views
18 Pages

Phenotypic Drug Discovery for Human African Trypanosomiasis: A Powerful Approach

  • Frederick S. Buckner,
  • Andriy Buchynskyy,
  • Pendem Nagendar,
  • Donald A. Patrick,
  • J. Robert Gillespie,
  • Zackary Herbst,
  • Richard R. Tidwell and
  • Michael H. Gelb

The work began with the screening of a library of 700,000 small molecules for inhibitors of Trypanosoma brucei growth (a phenotypic screen). The resulting set of 1035 hit compounds was reviewed by a team of medicinal chemists, leading to the nominati...

  • Article
  • Open Access
4 Citations
4,210 Views
8 Pages

Prevalence of Eye Problems among Young Infants of Rohingya Refugee Camps: Findings from a Cross-Sectional Survey

  • AHM Enayet Hussain,
  • Zunayed Al Azdi,
  • Khaleda Islam,
  • ANM Ehtesham Kabir and
  • Rumana Huque

Early detection of pediatric eye problems can prevent future vision loss. This study was to estimate the prevalence of common eye problems among infants born in a resource-constrained emergency setting with a broader aim to prevent future vision loss...

  • Review
  • Open Access
32 Citations
6,150 Views
12 Pages

Schistosomiasis affects about 240 million people worldwide and Schistosoma mansoni alone affects over 54 million people leaving 400 million at-risk especially in Sub Saharan Africa (SSA). About 20 million people are currently suffering from complicat...

  • Article
  • Open Access
7 Citations
3,875 Views
10 Pages

Gaps in Implementing Bidirectional Screening for Tuberculosis and Diabetes Mellitus in Myanmar: An Operational Research Study

  • Tun Kyaw Soe,
  • Kyaw Thu Soe,
  • Srinath Satyanarayana,
  • Saw Saw,
  • Cho Cho San and
  • Si Thu Aung

In Myanmar from July 2018, as a pilot project in 32 townships, all tuberculosis (TB) patients aged ≥40 years were eligible for diabetes mellitus (DM) screening by random blood sugar (RBS) and all DM patients attending hospitals were eligible for T...

  • Article
  • Open Access
10 Citations
4,692 Views
11 Pages

Antimicrobial resistance (AMR) is a global public health issue. Upper respiratory tract infections (URTIs) are common illnesses during Hajj, for which antibiotics are often inappropriately prescribed. Hajj healthcare workers’ (HCW) knowledge, attitud...

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Trop. Med. Infect. Dis. - ISSN 2414-6366