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Biomimetics, Volume 8, Issue 4

August 2023 - 52 articles

Cover Story: For nearly a century, fluoride has dominated dental products as an active ingredient but there is overwhelming evidence that other formulations work to improve oral health by reversing early dental decay, improving gum health, reducing tooth sensitivity and dental erosion, and safely whitening teeth. This review focuses on fluoride-free toothpastes containing biomimetic calcium phosphate-based molecules as the primary active ingredients. These include hydroxyapatite (HAP), casein phosphopeptide-amorphous calcium phosphate (CPP-ACP), calcium sodium phosphosilicate (CSPS, Bioglass or Novamin), β-tricalcium phosphate (β-TCP), and calcium glycerophosphate (CaGP). To date, 150 clinical trials on human subjects have shown the efficacy of calcium phosphates in biomimetic oral care. View this paper

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Review

24 Citations

17,455 Views

24 Pages

Improving Oral Health with Fluoride-Free Calcium-Phosphate-Based Biomimetic Toothpastes: An Update of the Clinical Evidence

Hardy Limeback,
Joachim Enax and
Frederic Meyer

Biomimetics2023, 8(4), 331;https://doi.org/10.3390/biomimetics8040331

27 July 2023

As the demand for clinically effective fluoride-free oral care products for consumers increases, it is important to document which types of toothpastes have been shown in clinical studies to be effective in improving oral health. In this review, we i...

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Review

28 Citations

4,527 Views

18 Pages

Recent Advances in the Production of Pharmaceuticals Using Selective Laser Sintering

Athinarayanan Balasankar,
Kandasamy Anbazhakan,
Velusamy Arul,
Velankadu Natrayan Mutharaian,
Ganesan Sriram,
Kanakaraj Aruchamy,
Tae Hwan Oh and
Subramaniyan Ramasundaram

Biomimetics2023, 8(4), 330;https://doi.org/10.3390/biomimetics8040330

27 July 2023

Selective laser sintering (SLS) is an additive manufacturing process that has shown promise in the production of medical devices, including hip cups, knee trays, dental crowns, and hearing aids. SLS-based 3D-printed dosage forms have the potential to...

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