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Fermentation, Volume 9, Issue 8

August 2023 - 82 articles

Cover Story: Baker’s yeast stands as an extensively characterized and versatile microorganism pivotal in biomanufacturing diverse specialty molecules, including enzymes, biofuels, chemicals and pharmaceuticals. Despite its genetic tractability, the evaluation of its sustained production prowess has remained understudied. Here, we introduced a fluorescent reporter gene on select genomic loci to monitor fluorescence levels across a span of over 100 generations. A clear decline in fluorescence over time was observed, yet what the underlying causes were warrants further investigation. Alongside this pioneering testament to the evolutionary dynamics of engineered yeast strains, we propose several new and strain-specific parameters to expedite microbial cell factory construction. View this paper
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Articles (82)

  • Article
  • Open Access
7 Citations
2,493 Views
15 Pages

Light Induction of Seed Culture Accelerates Lutein Accumulation in Heterotrophic Fermentation of Chlorella protothecoides CS-41

  • Yunlei Fu,
  • Lanbo Yi,
  • Shufang Yang,
  • Xue Lu,
  • Bin Liu,
  • Feng Chen,
  • Junchao Huang,
  • Kawing Cheng,
  • Han Sun and
  • Xiaolei Wu

Microalgae are recognized as a promising and valuable source of lutein. However, the current two-stage method for lutein production has drawbacks, such as complex operations and a long cultivation time. Additionally, utilizing heterotrophic fermentat...

  • Review
  • Open Access
2 Citations
6,645 Views
11 Pages

Scientific and Pharmaceutical Aspects of Christensenella minuta, a Promising Next-Generation Probiotic

  • Ágota Pető,
  • Dóra Kósa,
  • Zoltán Szilvássy,
  • Pálma Fehér,
  • Zoltán Ujhelyi,
  • Gabriella Kovács,
  • István Német,
  • István Pócsi and
  • Ildikó Bácskay

Christensenella minuta (C. minuta), a member of a recently described bacterial family, is one of the most heritable next-generation probiotics. Many observational studies confirmed that the relative abundance of C. minuta is associated with lean body...

  • Communication
  • Open Access
1 Citations
5,268 Views
11 Pages

A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Cholesterol-Lowering Effect of BBR 4401 in Adults with Moderate Hypercholesterolemia

  • Mincheol Kim,
  • Minjee Lee,
  • Min-Goo Kim,
  • Hayoung Kim,
  • Boyoung Choi,
  • Seongsik Kim,
  • Won-Yeong Bang,
  • Yong-Jin Kim,
  • Jungwoo Yang and
  • Hyun-Jae Kang

A randomized, double-blind, placebo-controlled trial was designed to assess the efficacy of the parabiotic Bifidobacterium breve IDCC 4401, named BBR 4401, for lowering cholesterol levels. The 66 subjects (per protocol set, n = 60) with low-density l...

  • Review
  • Open Access
18 Citations
8,843 Views
14 Pages

Lactic acid plays an important role in industrial applications ranging from the food industry to life sciences. The growing demand for lactic acid creates an urgent need to find economical and sustainable substrates for lactic acid production. Agricu...

  • Communication
  • Open Access
2 Citations
3,323 Views
11 Pages

Biosynthesis of Glucaric Acid by Recombinant Strain of Escherichia coli Expressing Two Different Urinate Dehydrogenases

  • Xinchao Yang,
  • Linlin Niu,
  • Chunjiang Ye,
  • Yuanxiu Wang,
  • Yuehui Liu,
  • Fang Wang and
  • Naxin Sun

D-glucaric acid is an important bio-based building block of polymers and is a high value-added chemical that can be used in a variety of applications. In the present study, the Udh target genes from Pseudomonas putida and Pseudomonas syringae were us...

  • Article
  • Open Access
6 Citations
3,206 Views
14 Pages

Kinetics of Formation of Butyric and Pyroglutamic Acid during the Shelf Life of Probiotic, Prebiotic and Synbiotic Yoghurt

  • Alessandra Aiello,
  • Lucia De Luca,
  • Fabiana Pizzolongo,
  • Gabriella Pinto,
  • Francesco Addeo and
  • Raffaele Romano

Butyric acid (C4) and pyroglutamic acid (pGlu) exert significant beneficial effects on human health. In this study, the influence of probiotics (Lactobacillus acidophilus and Bifidobacteria) and/or prebiotics (1 and 3% inulin and fructo-oligosacchari...

  • Review
  • Open Access
2 Citations
3,628 Views
22 Pages

Exploring the Fermentation-Driven Functionalities of Lactobacillaceae-Originated Probiotics in Preventive Measures of Alzheimer’s Disease: A Review

  • Anjali Tripathi,
  • Vinay Kumar Pandey,
  • Vivek Tiwari,
  • Rashi Mishra,
  • Kshirod Kumar Dash,
  • Endre Harsányi,
  • Béla Kovács and
  • Ayaz Mukarram Shaikh

Alzheimer’s disease (AD) is an ascending, neurodegenerative disorder that attacks the brain’s nerve cells, i.e., neurons, resulting in loss of memory, language skills, and thinking and behavioural changes. It is one of the most common cau...

  • Article
  • Open Access
6 Citations
2,899 Views
16 Pages

Lignocellulose Degrading Weizmannia coagulans Capable of Enantiomeric L-Lactic Acid Production via Consolidated Bioprocessing

  • Punnita Pamueangmun,
  • Aliyu Dantani Abdullahi,
  • Md. Humayun Kabir,
  • Kridsada Unban,
  • Apinun Kanpiengjai,
  • Joachim Venus,
  • Kalidas Shetty,
  • Chalermpong Saenjum and
  • Chartchai Khanongnuch

Second-generation lactic acid production requires the development of sustainable and economically feasible processes and renewable lignocellulose biomass as a starting raw material. Weizmannia coagulans MA42 was isolated from a soil sample in Chiang...

  • Article
  • Open Access
10 Citations
3,677 Views
14 Pages

In the present study, a total of eight Enterococcus faecium (OQ940301, OQ940302, OQ940303, OQ940304, OQ940305, OQ940308, OQ940309, and OQ940310) were isolated from soybean paste, a traditional Korean fermented food, and evaluated for their probiotic...

  • Article
  • Open Access
5 Citations
6,602 Views
20 Pages

The Effect of Yeast Inoculation Methods on the Metabolite Composition of Sauvignon Blanc Wines

  • Farhana R. Pinu,
  • Lily Stuart,
  • Taylan Topal,
  • Abby Albright,
  • Damian Martin and
  • Claire Grose

Evidence from the literature suggests that different inoculation strategies using either active dry yeast (ADY) or freshly prepared yeast cultures affect wine yeast performance, thus altering biomass and many primary and secondary metabolites produce...

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Fermentation - ISSN 2311-5637