Recent Advances in Transcatheter Closure of Atrial Septal Defects (ASD) and Ventricular Septal Defects (VSD)

A special issue of Journal of Cardiovascular Development and Disease (ISSN 2308-3425). This special issue belongs to the section "Pediatric Cardiology and Congenital Heart Disease".

Deadline for manuscript submissions: 30 September 2026 | Viewed by 1425

Special Issue Editors


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Guest Editor
Department of Pediatric and Adult Congenital Cardiology, IRCCS Policlinico San Donato, 20097 Milan, Italy
Interests: catheter interventions; congenital heart defects; PPV; Stents; ASD closure; VSD closure

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Guest Editor
Division of Cardiology, Hospital for Sick Children, Toronto, ON M5G 1E8, Canada
Interests: cardiac magnetic resonance imaging; computed tomography; 3D printing; mixed reality; 3D echocardiogram; congenital heart disease

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Guest Editor
Structural Heart Disease Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences, Beijing 100037, China
Interests: congenital heart disease; valvular heart disease; interventional treatment; Innovation in cardiovascular disease devices; artificial intelligence; mobile interventional surgery

Special Issue Information

Dear Colleagues,

Transcatheter closure of ASD and VSD have become an important part of interventional treatment of common congenital heart defects. Over the years, new devices and techniques have been developed, with substantial improvements in results:  device closure has proven to be possible not only for isolated secundum ASD, but also for multiple and complex  defects; more recently, very encouraging results have also been reported for percutaneous treatment of Sinus venosus defects, at least in selected patients. Similar progress was achieved for VSD closure, extending the possibility of successful closure in many anatomical defect variations, including muscular, perimembranous, and outlet defects. 

In addition, this Special Issue will focus on the dissemination of important information on preventing complications and bailout-preventing techniques when they occur. Descriptions of the aforementioned new devices/techniques will be provided by internationally recognized experts, including the pioneers experienced with reabsorbable devices.

Dr. Mario Carminati
Dr. Israel Valverde
Dr. Xiangbin Pan
Guest Editors

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Keywords

  • ASD
  • VSD
  • multiple septal defects
  • transcatheter closure
  • reabsorbable devices

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Published Papers (1 paper)

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Research

15 pages, 1052 KB  
Article
Muscular VSD Device Complications: Literature Review and Possible Implications for Echocardiographic Follow-Up
by Micah Tatum, Thomas Casto, Amulya Buddhavarapu, Elizabeth Lyman, Alison Gehred, Benjamin Blais and Clifford L. Cua
J. Cardiovasc. Dev. Dis. 2026, 13(3), 128; https://doi.org/10.3390/jcdd13030128 - 10 Mar 2026
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Abstract
Long-term transthoracic echocardiogram (TTE) follow-up guidelines after muscular ventricular septal defect (mVSD) device closure are vague. The primary goal of this study was to perform a literature search to characterize the type and timing of complications that occur after mVSD device placement. The [...] Read more.
Long-term transthoracic echocardiogram (TTE) follow-up guidelines after muscular ventricular septal defect (mVSD) device closure are vague. The primary goal of this study was to perform a literature search to characterize the type and timing of complications that occur after mVSD device placement. The search was performed in Medline (PubMed) with English language and publication date (1983 to 2024) filters applied. Studies were included if they reported on patients who underwent mVSD device closure. Studies were excluded if they reported on other types of ventricular septal defect (VSD) device closures, were review papers, or did not report outcomes after the device procedure. A total of 139 articles met the criteria (retrospective, n = 63; prospective, n = 10; case reports, n = 66), encompassing 1668 patient cases. Age at the time of mVSD closure was 10.6 + 2.7 years. Incidence of complications was 17.9% (299/1668). Maximum follow-up was 160 months. Most complications were residual shunts (40.8%, 122/299), followed by valve dysfunction (13.7%, 41/299) and arrhythmias (13.7% 41/299). The vast majority of complications occurred ≤12 months post-device placement 98.0% (293/299). Only 1.3% (4/299) of complications occurred at >12 months (mild tricuspid regurgitation, n = 2; left bundle branch block, n = 1; atrial fibrillation, n = 1). Time until complication was not reported in 0.7% (2/299) of patients (residual shunts, n = 2). All clinically significant complications diagnosed via TTE occurred <12 months post-mVSD device procedure. The utility of repeat TTE beyond one year after mVSD device closure should be reassessed if no clinical concerns are present. Full article
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