The Past, Present, and Future of Pulmonary Hypertension: Pathophysiology and Treatment Prospects

Dear Colleagues,

Pulmonary hypertension (PH) remains a complex and evolving disorder involving the pulmonary vasculature. This Special Issue explores the historical milestones that shaped our foundational understanding of PH, recent advances in diagnostic and therapeutic strategies, and future directions in treatment approaches.

This collection aims to provide a comprehensive overview of the changing landscape of PH. Topics may include translational genetics and metabolomics in PH physiology, current challenges in classification and risk stratification, and emerging therapies—from novel drug targets to precision medicine approaches. We invite contributions that reflect the depth of PH research, with the goal of inspiring continued innovation in improving outcomes for patients with this life-threatening condition.

Dr. Roxana Sulica
Dr. Himanshu Deshwal
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Cardiovascular Development and Disease is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.