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Journal of Cardiovascular Development and Disease, Volume 10, Issue 2

2023 February - 58 articles

Cover Story: Cryoballoon ablation is the most widely used single-shot method to achieve pulmonary vein isolation, the cornerstone of ablative therapy for atrial fibrillation. The two main prerequisites are proper balloon apposition to each ostium, leading to complete occlusion following inflation, and adequate energy administration, both of which in turn ensure lesion durability. In the present article, based on the experience from over 1000 procedures, we provide guidance concerning both procedural tips and tricks regarding manipulation of the ablation system to ensure stable venous occlusion, and values of specific biophysical parameters to be monitored and evaluated to determine whether lesion durability is achieved. Finally, we present evidence-based methods to avoid complications, as well as regarding patient management post-procedurally. View this paper
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Articles (58)

  • Systematic Review
  • Open Access
16 Citations
4,332 Views
13 Pages

Background: Mechanical prostheses and bioprosthetic prostheses have their own advantages and disadvantages. Mechanical ones are recommended for younger patients (<50 years old), and bioprosthetic ones are recommended for older patients (>70 yea...

  • Article
  • Open Access
2,365 Views
23 Pages

Intra-Individual Comparison of Sinus and Ectopic Beats Probing the Ventricular Gradient’s Activation Dependence

  • Resi M. Schoonderwoerd,
  • Mariëlle Dik,
  • Sumche Man,
  • Arie C. Maan,
  • J. Wouter Jukema and
  • Cees A. Swenne

Wilson assumed that the ventricular gradient (VG) is independent of the ventricular activation order. This paradigm has often been refuted and was never convincingly corroborated. We sought to validate Wilson’s concept by intra-individual compa...

  • Article
  • Open Access
2 Citations
2,796 Views
11 Pages

Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease

  • Enrique Castro Portillo,
  • Raúl López-Izquierdo,
  • Miguel A. Castro Villamor,
  • Ancor Sanz-García,
  • José L. Martín-Conty,
  • Begoña Polonio-López,
  • Irene Sánchez-Soberón,
  • Carlos del Pozo Vegas,
  • Carlos Durantez-Fernández and
  • Francisco Martín-Rodríguez
  • + 1 author

(1) Background: The Modified Sequential Organ Failure Assessment (mSOFA) is an Early Warning Score (EWS) that has proven to be useful in identifying patients at high risk of mortality in prehospital care. The main objective of this study was to evalu...

  • Article
  • Open Access
7 Citations
3,359 Views
20 Pages

Background: To preferably evaluate and predict the risk for in-hospital mortality in elderly patients receiving cardiac valvular surgery, we developed a new prediction model using least absolute shrinkage and selection operator (LASSO)-logistic regre...

  • Article
  • Open Access
3 Citations
4,090 Views
18 Pages

Intracoronary Administration of Microencapsulated HGF in a Reperfused Myocardial Infarction Swine Model

  • Virginia Blanco-Blázquez,
  • Claudia Báez-Díaz,
  • Francisco Miguel Sánchez-Margallo,
  • Irene González-Bueno,
  • Helena Martín,
  • Rebeca Blázquez,
  • Javier G. Casado,
  • Alejandra Usón,
  • Julia Solares and
  • Verónica Crisóstomo
  • + 2 authors

Therapy microencapsulation allows minimally invasive, safe, and effective administration. Hepatocyte growth factor (HGF) has angiogenic, anti-inflammatory, anti-apoptotic, and anti-fibrotic properties. Our objective was to evaluate the cardiac safety...

  • Article
  • Open Access
6 Citations
2,458 Views
14 Pages

Serum Catestatin Concentrations Are Increased in Patients with Atrial Fibrillation

  • Josip Katic,
  • Zrinka Jurisic,
  • Marko Kumric,
  • Josip A. Borovac,
  • Ante Anic,
  • Toni Breskovic,
  • Daniela Supe-Domic and
  • Josko Bozic

The autonomic nervous system is crucial in initiating and maintaining atrial fibrillation (AF). Catestatin is a multipurpose peptide that regulates cardiovascular systems and reduces harmful, excessive activity of the sympathetic nervous system by bl...

  • Article
  • Open Access
25 Citations
5,289 Views
14 Pages

Drug-Coated Balloon vs. Drug-Eluting Stents for De Novo Unprotected Left Main Stem Disease: The SPARTAN-LMS Study

  • Tharusha D. Gunawardena,
  • Natasha Corballis,
  • Ioannis Merinopoulos,
  • Upul Wickramarachchi,
  • Johannes Reinhold,
  • Clint Maart,
  • Sulfi Sreekumar,
  • Chris Sawh,
  • Trevor Wistow and
  • Simon Eccleshall
  • + 5 authors

The objective of this study is to compare the outcomes of patients treated with drug-coated balloons (DCBs) or second-generation drug-eluting stents (DESs) for de novo unprotected left main stem (LMS) disease. Previous studies comparing the treatment...

  • Brief Report
  • Open Access
4 Citations
3,750 Views
8 Pages

Returning to driving is one of the priorities for stroke survivors. However, the fear of the risk of recurrent stroke has led to concern about allowing driving post-stroke. This study was performed to study the impact of various vascular risk factors...

  • Article
  • Open Access
14 Citations
3,635 Views
15 Pages

Machine Learning to Identify Patients at Risk of Developing New-Onset Atrial Fibrillation after Coronary Artery Bypass

  • Orlando Parise,
  • Gianmarco Parise,
  • Akshayaa Vaidyanathan,
  • Mariaelena Occhipinti,
  • Ali Gharaviri,
  • Cecilia Tetta,
  • Elham Bidar,
  • Bart Maesen,
  • Jos G. Maessen and
  • Sandro Gelsomino
  • + 1 author

Background: This study aims to get an effective machine learning (ML) prediction model of new-onset postoperative atrial fibrillation (POAF) following coronary artery bypass grafting (CABG) and to highlight the most relevant clinical factors. Methods...

  • Article
  • Open Access
10 Citations
3,666 Views
13 Pages

Background: Heart transplantation represents the treatment for patients with end-stage heart failure (HF) being symptomatic despite optimal medical therapy. We investigated the role of NMR (neutrophil-to-monocyte ratio), NLR (neutrophil-to-lymphocyte...

  • Article
  • Open Access
5 Citations
3,926 Views
11 Pages

Developing a Questionnaire on Knowledge, Perceptions and Application of Vascular-Aging Measurements

  • Areti Triantafyllou,
  • Stavria-Artemis Elia,
  • Chloe Park,
  • Rachel E Climie,
  • Christopher C. Mayer,
  • Ioana Mozos,
  • Giacomo Pucci,
  • Thomas Weber and
  • Andrie G. Panayiotou

Background: Vascular age (VA) is independent and chronological age for assessing cardiovascular disease (CVD) risk. However, tools for the implementation of VA are currently lacking. We aimed to develop a questionnaire to assess the current knowledge...

  • Article
  • Open Access
10 Citations
3,735 Views
16 Pages

Expression Pattern and Molecular Mechanism of Oxidative Stress-Related Genes in Myocardial Ischemia–Reperfusion Injury

  • Jiahe Wu,
  • Jingyi Luo,
  • Huanhuan Cai,
  • Chenze Li,
  • Zhe Lei,
  • Yi Lu,
  • Lihua Ni,
  • Jianlei Cao,
  • Bo Cheng and
  • Xiaorong Hu

(1) Background: The molecular mechanism of oxidative stress-related genes (OSRGs) in myocardial ischemia–reperfusion injury (MIRI) has not been fully elucidated. (2) Methods: Differential expression analysis, enrichment analysis, and PPI analys...

  • Article
  • Open Access
15 Citations
3,280 Views
15 Pages

Maternal Serum tRNA-Derived Fragments (tRFs) as Potential Candidates for Diagnosis of Fetal Congenital Heart Disease

  • Enkang Lu,
  • Lijun Wu,
  • Bin Chen,
  • Shipeng Xu,
  • Ziyi Fu,
  • Yun Wu,
  • Yanhu Wu and
  • Haitao Gu

Background: Congenital heart disease (CHD) is one of the most predominant birth defects that causes infant death worldwide. The timely and successful surgical treatment of CHD on newborns after delivery requires accurate detection and reliable diagno...

  • Article
  • Open Access
4 Citations
2,746 Views
13 Pages

Background: Observational studies have found an association between increased whole body water mass (BWM) and atrial fibrillation (AF). However, the causality has yet to be confirmed. To provide feasible protective measures on disease development, we...

  • Article
  • Open Access
4 Citations
2,259 Views
11 Pages

Does an eHealth Intervention Reduce Complications and Healthcare Resources? A mHeart Single-Center Randomized-Controlled Trial

  • Mar Gomis-Pastor,
  • Sonia Mirabet Perez,
  • Anna De Dios Lopez,
  • Vicenç Brossa Loidi,
  • Laura Lopez Lopez,
  • Rebeca Pelegrin Cruz and
  • Mª Antonia Mangues Bafalluy

(1) Background: In the mHeart trial, we showed that an eHealth intervention, mHeart, improved heart transplant (HTx) recipients’ adherence to immunosuppressive therapy compared with the standard of care. Herein, we present the analysis assessin...

  • Article
  • Open Access
2 Citations
2,057 Views
13 Pages

The study aimed to determine the effectiveness and safety of anomalous coronary artery from pulmonary artery (ACAPA) patients with moderate or severe mitral valve regurgitation (MVR) receiving mitral valve plasty (MVP) concurrently. Consecutive ACAPA...

  • Review
  • Open Access
54 Citations
8,644 Views
15 Pages

Artificial Intelligence in Hypertension Management: An Ace up Your Sleeve

  • Valeria Visco,
  • Carmine Izzo,
  • Costantino Mancusi,
  • Antonella Rispoli,
  • Michele Tedeschi,
  • Nicola Virtuoso,
  • Angelo Giano,
  • Renato Gioia,
  • Americo Melfi and
  • Michele Ciccarelli
  • + 8 authors

Arterial hypertension (AH) is a progressive issue that grows in importance with the increased average age of the world population. The potential role of artificial intelligence (AI) in its prevention and treatment is firmly recognized. Indeed, AI app...

  • Article
  • Open Access
3,223 Views
13 Pages

Nomogram and Risk Calculator for Postoperative Tracheostomy after Heart Valve Surgery

  • Xiangchao Ding,
  • Bing Sun,
  • Liang Liu,
  • Yuan Lei and
  • Yunshu Su

Postoperative tracheostomy (POT) is an important indicator of critical illness, associated with poorer prognoses and increased medical burdens. However, studies on POTs after heart valve surgery (HVS) have not been reported. The objectives of this st...

  • Review
  • Open Access
9 Citations
4,925 Views
10 Pages

The Cardiac Effects of COVID-19 on Young Competitive Athletes: Results from the Outcomes Registry for Cardiac Conditions in Athletes (ORCCA)

  • Nathaniel Moulson,
  • Bradley J. Petek,
  • Aaron L. Baggish,
  • Kimberly G. Harmon,
  • Stephanie A. Kliethermes,
  • Manesh R. Patel,
  • Timothy W. Churchill and
  • Jonathan A. Drezner

The Outcomes Registry for Cardiac Conditions in Athletes (ORCCA) study is a large-scale prospective investigation evaluating the cardiovascular effects and outcomes of SARS-CoV-2 infection on young competitive athletes. This review provides an overvi...

  • Article
  • Open Access
1 Citations
2,686 Views
14 Pages

Ticagrelor Can Regulate the Ion Channel Characteristics of Superior Cervical Ganglion Neurons after Myocardial Infarction

  • Lijun Cheng,
  • Lin Yu,
  • Xiaoping Zhan,
  • Gary Tse,
  • Tong Liu,
  • Huaying Fu and
  • Guangping Li

Background: The superior cervical ganglion (SCG) plays a key role in cardiovascular diseases. The aim of this study was to determine the changes in the ion channel characteristics of the SCG following myocardial infarction (MI) and the role of pretre...

  • Article
  • Open Access
6 Citations
3,079 Views
11 Pages

Aim: To assess changes in blood pressure (BP) and arterial stiffness among 84 rotating shift and 25 dayworkers (control subjects) at two industrial plants during a 4-year follow-up, and to assess changes in outcome variables among shift workers at th...

  • Article
  • Open Access
2 Citations
2,626 Views
9 Pages

In Vitro Comparison of Several Thrombus Removal Tools

  • Katarzyna Pigoń,
  • Natalia Tomecka,
  • Dominika Korner,
  • Maciej Pękała,
  • Sławomir Grzegorczyn,
  • Adam Konka,
  • Ewa Nowalany-Kozielska and
  • Andrzej Tomasik

Background: Although the routine use of thrombus aspiration is not recommended, the thrombectomy technique still might be considered for a selected population of patients. Therefore, the assessment of the effectiveness of commercially available throm...

  • Review
  • Open Access
39 Citations
22,890 Views
16 Pages

Sudden Cardiac Death in Athletes: Facts and Fallacies

  • Jennie Han,
  • Andrea Lalario,
  • Enzo Merro,
  • Gianfranco Sinagra,
  • Sanjay Sharma,
  • Michael Papadakis and
  • Gherardo Finocchiaro

The benefits of exercise for cardiovascular and general health are many. However, sudden cardiac death (SCD) may occur in apparently healthy athletes who perform at the highest levels. A diverse spectrum of diseases is implicated in SCD in athletes,...

  • Article
  • Open Access
11 Citations
3,889 Views
11 Pages

Virtual Reality Simulator versus Conventional Advanced Life Support Training for Cardiopulmonary Resuscitation Post-Cardiac Surgery: A Randomized Controlled Trial

  • Jette J. Peek,
  • Samuel A. Max,
  • Wouter Bakhuis,
  • Isabelle C. Huig,
  • Rodney A. Rosalia,
  • Amir H. Sadeghi and
  • Edris A. F. Mahtab

External chest compressions are often ineffective for patients arresting after cardiac surgery, for whom emergency resternotomy may be required. A single-blinded randomized controlled trial (RCT) was performed, with participants being randomized to a...

  • Systematic Review
  • Open Access
13 Citations
6,931 Views
16 Pages

Direct Oral Anticoagulants as the First Choice of Anticoagulation for Patients with Peripheral Artery Disease to Prevent Adverse Vascular Events: A Systematic Review and Meta-Analysis

  • Enikő Pomozi,
  • Rita Nagy,
  • Péter Fehérvári,
  • Péter Hegyi,
  • Boldizsár Kiss,
  • Fanni Dembrovszky,
  • Annamária Kosztin,
  • Sándor Nardai,
  • Endre Zima and
  • Zoltán Szeberin

The best method of anticoagulation for patients with peripheral artery disease (PAD) is still a topic of interest for physicians. We conducted a meta-analysis to compare the effects of direct oral anticoagulants (DOACs) with those of vitamin-K-antago...

  • Article
  • Open Access
1 Citations
4,812 Views
14 Pages

The Relationship between Postexercise Hypotension and Heart Rate Variability before and after Exercise Training

  • Burak T. Cilhoroz,
  • Amanda Zaleski,
  • Beth Taylor,
  • Antonio B. Fernandez,
  • Lucas P. Santos,
  • Thijs Vonk,
  • Paul D. Thompson and
  • Linda S. Pescatello

Because data are scarce, we examined the relationship between postexercise hypotension (PEH) and heart rate variability (HRV) before and after aerobic exercise training among adults with hypertension. Participants completed a 12 w aerobic training pr...

  • Brief Report
  • Open Access
8 Citations
2,442 Views
8 Pages

Association between Femoral Artery Flow-Mediated Dilation and Muscle Oxygen Saturation Parameters in Healthy, Young Individuals

  • Vivian dos Santos Pinheiro,
  • Anna Carolina Faria da Silva Tavares,
  • Mônica Volino-Souza,
  • Gustavo Vieira de Oliveira and
  • Thiago Silveira Alvares

Flow-mediated dilation (FMD) and muscle oxygen saturation (StO2) are measurements utilized to assess macro- and microvascular function, respectively. Macro- and microvascular dysfunction may occur differently depending on the clinical condition. Sinc...

  • Article
  • Open Access
10 Citations
4,498 Views
10 Pages

Impact of Systematic Use of Intracardiac Ultrasound during Transseptal Catheterization in the Electrophysiology Laboratory

  • Nicola Bottoni,
  • Paolo Donateo,
  • Luca Rossi,
  • Michele Malagù,
  • Luca Tomasi,
  • Fabio Quartieri,
  • Andrea Biagi,
  • Matteo Iori,
  • Giacomo Mugnai and
  • Matteo Bertini
  • + 3 authors

Aims: To explore the impact of the use of intracardiac echocardiography (ICE) in the ablation of supraventricular arrhythmias requiring transseptal catheterization (TSC), whilst analyzing the reduction in periprocedural complications and complication...

  • Editorial
  • Open Access
2,418 Views
8 Pages

The medical approach to atrial fibrillation (AF) underwent a paradigm shift over time, evolving from considering AF as a simple arrhythmic phenomenon to a complex nosological entity [...]

  • Article
  • Open Access
5 Citations
2,182 Views
12 Pages

Predictive Ability of the National Early Warning Score in Mortality Prediction of Acute Pulmonary Embolism in the Southeast Asian Population

  • Chaiwat Bumroongkit,
  • Pattraporn Tajarernmuang,
  • Konlawij Trongtrakul,
  • Chalerm Liwsrisakun,
  • Athavudh Deesomchok,
  • Chaicharn Pothirat,
  • Theerakorn Theerakittikul,
  • Atikun Limsukon,
  • Nutchanok Niyatiwatchanchai and
  • Warawut Chaiwong
  • + 1 author

Background: The National Early Warning Scores (NEWS) easily and objectively measures acute clinical deterioration. However, the performance of NEWS to predict mortality in patients with acute pulmonary embolism (APE) is still required. Therefore, the...

  • Case Report
  • Open Access
1 Citations
2,276 Views
7 Pages

“Floating” Stent in a Coronary Aneurysm Presenting as ST-Elevation Myocardial Infarction

  • Daniel De Castro,
  • Sergio García-Gómez,
  • Fernando Domínguez,
  • Carlos Arellano and
  • Juan Francisco Oteo

Coronary artery aneurysm (CAA) presenting as an ST-elevation myocardial infarction (STEMI) represents a clinical challenge due to the technical difficulties in the percutaneous management of this specific situation. Appropriate treatment for CAA depe...

  • Article
  • Open Access
3 Citations
2,500 Views
8 Pages

Electrocardiographic Pathological Findings Caused by the SARS-CoV-2 Virus Infection: Evidence from a Retrospective Multicenter International Cohort Longitudinal Pilot Study of 548 Subjects

  • Nicola Susca,
  • Antonio Giovanni Solimando,
  • Paola Borrelli,
  • Donatello Marziliano,
  • Francesco Monitillo,
  • Pasquale Raimondo,
  • Domenico Vestito,
  • Agostino Lopizzo,
  • Gaetano Brindicci and
  • Francesco Santoro
  • + 6 authors

COVID-19 has threatened the capability of receiving and allocating patients in emergency departments (EDs) all over the world. This is a retrospective cohort study to explore the role of a simple procedure like an ECG to screen for the severity of CO...

  • Article
  • Open Access
2 Citations
4,298 Views
13 Pages

Socioeconomic Macro-Level Determinants of Hypertension: Ecological Analysis of 138 Low- and Middle-Income Countries

  • Mustapha S. Abba,
  • Chidozie U. Nduka,
  • Seun Anjorin,
  • Fatima H. Zanna and
  • Olalekan A. Uthman

Aim: To assess the relative importance of major socioeconomic determinants of population health on the burden of hypertension in Low-and-Middle-Income Countries (LMICs). Methods: Country-level data from 138 countries based on World Development Indica...

  • Article
  • Open Access
7 Citations
2,803 Views
22 Pages

The non-thermal effects are considered one of the prominent advantages of pulsed field ablation (PFA). However, at higher PFA doses, the temperature rise in the tissue during PFA may exceed the thermal damage threshold, at which time intracardiac pul...

  • Review
  • Open Access
7 Citations
6,595 Views
20 Pages

Best Practice Guide for Cryoballoon Ablation in Atrial Fibrillation: The Compilation Experience of More than 1000 Procedures

  • Dimitriοs Tsiachris,
  • Christos-Konstantinos Antoniou,
  • Ioannis Doundoulakis,
  • Panagiota Manolakou,
  • Demetrios Sougiannis,
  • Athanasios Kordalis,
  • Konstantinos A. Gatzoulis,
  • Gian-Battista Chierchia,
  • Carlo de Asmundis and
  • Konstantinos Tsioufis
  • + 1 author

Nowadays, the cryoballoon (CB) constitutes an established alternative to radio frequency (RF) ablation for pulmonary vein isolation (PVI), which offers the possibility to isolate the PVs with a single application. Since the introduction of the second...

  • Article
  • Open Access
14 Citations
4,109 Views
14 Pages

Metformin Directly Binds to MMP-9 to Improve Plaque Stability

  • Xianda Chen,
  • Shuaixing Wang,
  • Wenli Xu,
  • Mingming Zhao,
  • Youyi Zhang and
  • Han Xiao

Vulnerable atherosclerotic plaque rupture is the principal mechanism that accounts for myocardial infarction and stroke. High matrix metalloproteinase-9 (MMP-9) expression and activity have been proven to lead to plaque instability. Metformin, a firs...

  • Article
  • Open Access
11 Citations
5,609 Views
20 Pages

Ciclopirox Inhibition of eIF5A Hypusination Attenuates Fibroblast Activation and Cardiac Fibrosis

  • Kadiam C. Venkata Subbaiah,
  • Jiangbin Wu,
  • Wai Hong Wilson Tang and
  • Peng Yao

Cardiac fibrosis is a primary contributor to heart failure (HF), and is considered to be a targetable process for HF therapy. Cardiac fibroblast (CF) activation accompanied by excessive extracellular matrix (ECM) production is central to the initiati...

  • Article
  • Open Access
2 Citations
3,789 Views
11 Pages

Target Balloon-Assisted Antegrade and Retrograde Use of Re-Entry Catheters in Complex Chronic Total Occlusions

  • Lorenzo Patrone,
  • Nada Selva Theivacumar,
  • Brahman Dharmarajah,
  • Narayanan Thulasidasan,
  • Athanasios Diamantopoulos,
  • Luis Mariano Palena,
  • Muliadi Antaredja,
  • Lisa Tilemann and
  • Erwin Blessing

Purpose, Retrograde recanalizations have gained increasing recognition in complex arterial occlusive disease. Re-entry devices are a well described adjunct for antegrade recanalizations. We present our experience with target balloon-assisted antegrad...

  • Perspective
  • Open Access
2 Citations
4,599 Views
10 Pages

A frog is a classical model organism used to uncover processes and regulations of early vertebrate development, including heart development. Recently, we showed that a frog also represents a useful model to study a rare human congenital heart disease...

  • Article
  • Open Access
6 Citations
4,952 Views
15 Pages

Paresis of the upper and lower limbs is a typical issue in stroke survivors. This study aims to determine whether core exercises help stroke survivors with very severe motor impairment recover their motor function. This study employed a within-subjec...

  • Article
  • Open Access
1 Citations
7,678 Views
12 Pages

The Prognostic Value of Pulmonary Venous Flow Reversal in Patients with Significant Degenerative Mitral Regurgitation

  • Alon Shechter,
  • Steele C. Butcher,
  • Robert J. Siegel,
  • Jenan Awesat,
  • Merry Abitbol,
  • Mordehay Vaturi,
  • Alex Sagie,
  • Ran Kornowski,
  • Yaron Shapira and
  • Idit Yedidya

Background: The prognostic significance of pulmonary venous (PV) flow reversal in degenerative mitral regurgitation (dMR) is not well-established. Objective: We aimed to assess whether reversed PV flow is associated with adverse outcomes in patients...

  • Article
  • Open Access
15 Citations
3,833 Views
15 Pages

Prediction and Analysis of Heart Failure Decompensation Events Based on Telemonitored Data and Artificial Intelligence Methods

  • Jon Kerexeta,
  • Nekane Larburu,
  • Vanessa Escolar,
  • Ainara Lozano-Bahamonde,
  • Iván Macía,
  • Andoni Beristain Iraola and
  • Manuel Graña

Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. Heart failure (HF) occurs when the heart is not able to pump enough blood to satisfy metabolic needs. People diagnosed with chronic HF...

  • Review
  • Open Access
8 Citations
3,277 Views
15 Pages

Early Mortality in Infants Born with Neonatally Operated Congenital Heart Defects and Low or Very-Low Birthweight: A Systematic Review and Meta-Analysis

  • Neil Derridj,
  • Ali Ghanchi,
  • Damien Bonnet,
  • Pauline Adnot,
  • Makan Rahshenas,
  • Laurent J. Salomon,
  • Jérémie F. Cohen and
  • Babak Khoshnood

Mortality outcomes of children with isolated neonatally operated congenital heart defects (CHDs) born with a low (LBW), moderately low (MLBW) or very-low birthweight (VLBW) remain ambiguous. We searched Medline and Embase (inception until October 202...

  • Review
  • Open Access
14 Citations
4,804 Views
15 Pages

Role of Echocardiography in Diabetic Cardiomyopathy: From Mechanisms to Clinical Practice

  • Hrvoje Urlic,
  • Marko Kumric,
  • Josip Vrdoljak,
  • Dinko Martinovic,
  • Goran Dujic,
  • Marino Vilovic,
  • Tina Ticinovic Kurir and
  • Josko Bozic

It has been well established that diabetes mellitus (DM) is considered as a core risk factor for the development of cardiovascular diseases. However, what is less appreciated is the fact that DM may affect cardiac function irrespective of cardiac pat...

  • Article
  • Open Access
7 Citations
2,416 Views
21 Pages

Brachial Blood Pressure Invasively and Non-Invasively Obtained Using Oscillometry and Applanation Tonometry: Impact of Mean Blood Pressure Equations and Calibration Schemes on Agreement Levels

  • Daniel Bia,
  • Yanina Zócalo,
  • Ramiro Sánchez,
  • Juan F. Torrado,
  • Gustavo Lev,
  • Oscar Mendiz,
  • Franco Pessana,
  • Agustín Ramírez and
  • Edmundo I. Cabrera-Fischer

The use of oscillometric methods to determine brachial blood pressure (bBP) can lead to a systematic underestimation of the invasively measured systolic (bSBP) and pulse (bPP) pressure levels, together with a significant overestimation of diastolic p...

  • Article
  • Open Access
12 Citations
4,339 Views
16 Pages

Pulse wave velocity (PWV), a direct measure of arterial stiffness, is a promising biomarker of cardiovascular risk and a cardiovascular surrogate outcome. The resolution for detecting its smallest clinically significant change is dependent on the exp...

  • Editorial
  • Open Access
1 Citations
1,812 Views
4 Pages

The Roles of Coronary Computed Tomography Angiography in Characterizing Coronary Plaque: Screening, Treatment, and Prevention

  • Issa Pour-Ghaz,
  • Deya Alkhatib,
  • Sakiru Isa,
  • Omar Al-Taweel,
  • Ifeoma Ugonabo,
  • Neeraja Yedlapati and
  • John Lynn Jefferies

One of the major risk factors for coronary atherosclerosis is the gradual formation and maturation of coronary atherosclerotic plaque (CAP) [...]

  • Article
  • Open Access
5 Citations
3,188 Views
13 Pages

While age is an important risk factor, there are some disadvantages to including it in a stroke risk model: age can dominate the risk score and lead to over- or under-predictions in some age groups. There is evidence to suggest that some of these dis...

  • Review
  • Open Access
4 Citations
4,727 Views
17 Pages

Anticoagulation for Left Ventricle Thrombus—Case Series and Literature Review for Use of Direct Oral Anticoagulants

  • Akshyaya Pradhan,
  • Monika Bhandari,
  • Pravesh Vishwakarma,
  • Chiara Salimei,
  • Ferdinando Iellamo,
  • Rishi Sethi and
  • Marco Alfonso Perrone

Left ventricular thrombus is a known complication following acute myocardial infarction that can lead to systemic thromboembolism. To obviate the risk of thromboembolism, the patient needs anticoagulation in addition to dual antiplatelet therapy. How...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425