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Journal of Cardiovascular Development and Disease, Volume 10, Issue 2

February 2023 - 58 articles

Cover Story: Cryoballoon ablation is the most widely used single-shot method to achieve pulmonary vein isolation, the cornerstone of ablative therapy for atrial fibrillation. The two main prerequisites are proper balloon apposition to each ostium, leading to complete occlusion following inflation, and adequate energy administration, both of which in turn ensure lesion durability. In the present article, based on the experience from over 1000 procedures, we provide guidance concerning both procedural tips and tricks regarding manipulation of the ablation system to ensure stable venous occlusion, and values of specific biophysical parameters to be monitored and evaluated to determine whether lesion durability is achieved. Finally, we present evidence-based methods to avoid complications, as well as regarding patient management post-procedurally. View this paper
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Articles (58)

  • Systematic Review
  • Open Access
16 Citations
4,248 Views
13 Pages

Background: Mechanical prostheses and bioprosthetic prostheses have their own advantages and disadvantages. Mechanical ones are recommended for younger patients (<50 years old), and bioprosthetic ones are recommended for older patients (>70 yea...

  • Article
  • Open Access
2,304 Views
23 Pages

Intra-Individual Comparison of Sinus and Ectopic Beats Probing the Ventricular Gradient’s Activation Dependence

  • Resi M. Schoonderwoerd,
  • Mariëlle Dik,
  • Sumche Man,
  • Arie C. Maan,
  • J. Wouter Jukema and
  • Cees A. Swenne

Wilson assumed that the ventricular gradient (VG) is independent of the ventricular activation order. This paradigm has often been refuted and was never convincingly corroborated. We sought to validate Wilson’s concept by intra-individual compa...

  • Article
  • Open Access
1 Citations
2,723 Views
11 Pages

Modified Sequential Organ Failure Assessment Score vs. Early Warning Scores in Prehospital Care to Predict Major Adverse Cardiac Events in Acute Cardiovascular Disease

  • Enrique Castro Portillo,
  • Raúl López-Izquierdo,
  • Miguel A. Castro Villamor,
  • Ancor Sanz-García,
  • José L. Martín-Conty,
  • Begoña Polonio-López,
  • Irene Sánchez-Soberón,
  • Carlos del Pozo Vegas,
  • Carlos Durantez-Fernández and
  • Rosa Conty-Serrano
  • + 1 author

(1) Background: The Modified Sequential Organ Failure Assessment (mSOFA) is an Early Warning Score (EWS) that has proven to be useful in identifying patients at high risk of mortality in prehospital care. The main objective of this study was to evalu...

  • Article
  • Open Access
7 Citations
3,250 Views
20 Pages

Background: To preferably evaluate and predict the risk for in-hospital mortality in elderly patients receiving cardiac valvular surgery, we developed a new prediction model using least absolute shrinkage and selection operator (LASSO)-logistic regre...

  • Article
  • Open Access
3 Citations
3,967 Views
18 Pages

Intracoronary Administration of Microencapsulated HGF in a Reperfused Myocardial Infarction Swine Model

  • Virginia Blanco-Blázquez,
  • Claudia Báez-Díaz,
  • Francisco Miguel Sánchez-Margallo,
  • Irene González-Bueno,
  • Helena Martín,
  • Rebeca Blázquez,
  • Javier G. Casado,
  • Alejandra Usón,
  • Julia Solares and
  • Itziar Palacios
  • + 2 authors

Therapy microencapsulation allows minimally invasive, safe, and effective administration. Hepatocyte growth factor (HGF) has angiogenic, anti-inflammatory, anti-apoptotic, and anti-fibrotic properties. Our objective was to evaluate the cardiac safety...

  • Article
  • Open Access
6 Citations
2,411 Views
14 Pages

Serum Catestatin Concentrations Are Increased in Patients with Atrial Fibrillation

  • Josip Katic,
  • Zrinka Jurisic,
  • Marko Kumric,
  • Josip A. Borovac,
  • Ante Anic,
  • Toni Breskovic,
  • Daniela Supe-Domic and
  • Josko Bozic

The autonomic nervous system is crucial in initiating and maintaining atrial fibrillation (AF). Catestatin is a multipurpose peptide that regulates cardiovascular systems and reduces harmful, excessive activity of the sympathetic nervous system by bl...

  • Article
  • Open Access
23 Citations
5,203 Views
14 Pages

Drug-Coated Balloon vs. Drug-Eluting Stents for De Novo Unprotected Left Main Stem Disease: The SPARTAN-LMS Study

  • Tharusha D. Gunawardena,
  • Natasha Corballis,
  • Ioannis Merinopoulos,
  • Upul Wickramarachchi,
  • Johannes Reinhold,
  • Clint Maart,
  • Sulfi Sreekumar,
  • Chris Sawh,
  • Trevor Wistow and
  • Toomas Sarev
  • + 5 authors

The objective of this study is to compare the outcomes of patients treated with drug-coated balloons (DCBs) or second-generation drug-eluting stents (DESs) for de novo unprotected left main stem (LMS) disease. Previous studies comparing the treatment...

  • Brief Report
  • Open Access
3 Citations
3,650 Views
8 Pages

Returning to driving is one of the priorities for stroke survivors. However, the fear of the risk of recurrent stroke has led to concern about allowing driving post-stroke. This study was performed to study the impact of various vascular risk factors...

  • Article
  • Open Access
13 Citations
3,536 Views
15 Pages

Machine Learning to Identify Patients at Risk of Developing New-Onset Atrial Fibrillation after Coronary Artery Bypass

  • Orlando Parise,
  • Gianmarco Parise,
  • Akshayaa Vaidyanathan,
  • Mariaelena Occhipinti,
  • Ali Gharaviri,
  • Cecilia Tetta,
  • Elham Bidar,
  • Bart Maesen,
  • Jos G. Maessen and
  • Mark La Meir
  • + 1 author

Background: This study aims to get an effective machine learning (ML) prediction model of new-onset postoperative atrial fibrillation (POAF) following coronary artery bypass grafting (CABG) and to highlight the most relevant clinical factors. Methods...

  • Article
  • Open Access
10 Citations
3,593 Views
13 Pages

Background: Heart transplantation represents the treatment for patients with end-stage heart failure (HF) being symptomatic despite optimal medical therapy. We investigated the role of NMR (neutrophil-to-monocyte ratio), NLR (neutrophil-to-lymphocyte...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425