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Toxics, Volume 11, Issue 5

2023 May - 75 articles

Cover Story: Triclosan (TCS), a commonly used antibacterial preservative, has been demonstrated to have high toxicological potential and adversely affects water bodies. Since microalgae are one of the most significant primary producers on the planet, understanding the toxicological processes of TCS is critical for determining its risk in aquatic ecosystems and managing water environments. The molecular toxicity mechanism effect of TCS on Euglena gracilis was investigated by transcriptomics technology. A decrease in photosynthetic pigments, oxidative damage and inhibition of the tricarboxylic acid-related cycle metabolic pathway were detected in algal cells, which provide fundamental data and recommendations for TCS ecological risk assessment. View this paper
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Articles (75)

  • Article
  • Open Access
6 Citations
2,926 Views
13 Pages

Amelioration of Hepatotoxic and Neurotoxic Effect of Cartap by Aloe vera in Wistar Rats

  • Vivek Kumar Gupta,
  • Uichang Park,
  • Nikhat J. Siddiqi,
  • Yun Suk Huh and
  • Bechan Sharma

22 May 2023

Pesticide exposure can pose a serious risk to nontarget animals. Cartap is being broadly used in agricultural fields. The toxic effects of cartap on the levels of hepatotoxicity and neurotoxicity have not been properly studied in mammalian systems. T...

  • Feature Paper
  • Article
  • Open Access
6 Citations
3,375 Views
12 Pages

20 May 2023

Valproic acid (VPA) is a histone deacetylase inhibitor that is used mainly as an antiepileptic and anticonvulsant drug. The side effects of VPA usually appears as hepatic injury and various metabolic disorders. On the other hand, it is rarely reporte...

  • Article
  • Open Access
10 Citations
2,576 Views
14 Pages

In Vitro Genotoxicity Evaluation of PAHs in Mixtures Using Experimental Design

  • Rebecca Castel,
  • Virginie Tassistro,
  • Magalie Claeys-Bruno,
  • Laure Malleret and
  • Thierry Orsière

19 May 2023

Settled dusts are sinks for environmental pollutants, including Polycyclic Aromatic Hydrocarbons (PAHs) that are ubiquitous, persistent, and carcinogenic. To assess their toxicity in mixtures, Toxic Equivalent Factors (TEFs) are routinely used and ba...

  • Article
  • Open Access
14 Citations
3,468 Views
12 Pages

19 May 2023

The increasing concern for the ecological risks of microplastics (MPs) as carriers of hydrophobic organic contaminants is evident. Di-butyl phthalate (DBP) is extensively utilized as an additive in plastic products, and both DBP and MPs are widesprea...

  • Article
  • Open Access
13 Citations
3,916 Views
18 Pages

19 May 2023

Heavy metals as toxic pollutants have important impacts on the photosynthesis of microalgae, thus seriously threatening the normal material circulation and energy flow of the aquatic ecosystem. In order to rapidly and sensitively detect the toxicity...

  • Article
  • Open Access
6 Citations
2,829 Views
13 Pages

18 May 2023

In recent years, polybutylene adipate-co-terephthalate (PBAT) mulch film has become one of the most commonly used biodegradable mulch films in agriculture in an attempt to combat plastic film pollution. However, its degradation characteristics and im...

  • Feature Paper
  • Article
  • Open Access
5 Citations
2,648 Views
12 Pages

The Levels of Polycyclic Aromatic Hydrocarbons and Their Derivatives in Plasma and Their Effect on Mitochondrial DNA Methylation in the Oilfield Workers

  • Yaning Jia,
  • Weixia Li,
  • Yanlin Li,
  • Lei Zhao,
  • Chenguang Li,
  • Lei Wang,
  • Junkai Fang,
  • Shanjun Song,
  • Yaqin Ji and
  • Penghui Li
  • + 3 authors

17 May 2023

This study focuses on the components and levels of polycyclic aromatic hydrocarbons (PAHs) and their derivatives (MPAHs and OPAHs) in plasma samples from 19 oil workers, pre- and post-workshift, and their exposure–response relationship with mit...

  • Article
  • Open Access
9 Citations
2,736 Views
15 Pages

17 May 2023

Cigarette smoke is a major risk factor for gastric cancer. Exosomes are an important part of intercellular and intra-organ communication systems and can carry circRNA and other components to play a regulatory role in the occurrence and development of...

  • Case Report
  • Open Access
4 Citations
6,541 Views
6 Pages

Transdermal Nicotine Poisoning: A Rare Case Report of Occupational Exposure

  • Jenny Becam,
  • Edouard Martin,
  • Gildas Pouradier,
  • Natalia Doudka,
  • Caroline Solas,
  • Romain Guilhaumou and
  • Nicolas Fabresse

17 May 2023

We report a case of accidental nicotine intoxication following transdermal exposure in a 22-year-old man with no medical history, who worked in a company manufacturing e-liquids for electronic cigarettes. He accidentally spilled 300 mL of pure nicoti...

  • Feature Paper
  • Article
  • Open Access
16 Citations
4,985 Views
19 Pages

Category-Based Toxicokinetic Evaluations of Data-Poor Per- and Polyfluoroalkyl Substances (PFAS) using Gas Chromatography Coupled with Mass Spectrometry

  • Anna Kreutz,
  • Matthew S. Clifton,
  • W. Matthew Henderson,
  • Marci G. Smeltz,
  • Matthew Phillips,
  • John F. Wambaugh and
  • Barbara A. Wetmore

16 May 2023

Concern over per- and polyfluoroalkyl substances (PFAS) has increased as more is learned about their environmental presence, persistence, and bioaccumulative potential. The limited monitoring, toxicokinetic (TK), and toxicologic data available are in...

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Toxics - ISSN 2305-6304