You are currently viewing a new version of our website. To view the old version click .

Antibiotics, Volume 14, Issue 7

July 2025 - 110 articles

Cover Story: Platelet concentrates (PCs), used to treat patients with bleeding disorders, are stored at 20–24 °C to maintaining platelet functionality. These conditions also sustain the growth of bacteria such as Staphylococcus aureus, which poses an important safety risk to transfusion patients as it reaches clinically significant levels and produces virulence factors during PC storage. Previous studies have demonstrated that Staphylococcus spp. grown in PCs display upregulation of genes encoding for antimicrobial resistance and virulence. To expand the current knowledge, this study aimed to test whether the increase in the norB efflux pump expression observed in PCs translates into heightened quinolone resistance. Furthermore, the role of the NorB efflux pump on S. aureus virulence was investigated using a Bombyx mori (silkworm) animal model. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (110)

  • Article
  • Open Access
1,751 Views
14 Pages

Outcomes of Implementing a Multidimensional Antimicrobial Stewardship Program in a Medical Ward in a Third-Level University Hospital in Northern Italy

  • Maria Mazzitelli,
  • Daniele Mengato,
  • Gianmaria Barbato,
  • Sara Lo Menzo,
  • Fabio Dalla Valle,
  • Margherita Boschetto,
  • Paola Stano,
  • Cristina Contessa,
  • Daniele Donà and
  • Vincenzo Scaglione
  • + 8 authors

Background/Objectives: Antimicrobial stewardship programs (ASPs) optimize antimicrobial use, improving outcomes and reducing resistance. This study assessed the impact of a ward-specific ASP. Methods: A pre/post quasi-experimental study was conducted...

  • Article
  • Open Access
1,279 Views
15 Pages

In Vitro Susceptibility to Imipenem/Relebactam and Comparators in a Multicentre Collection of Mycobacterium abscessus Complex Isolates

  • Alejandro Seoane-Estévez,
  • Pablo Aja-Macaya,
  • Andrea Garcia-Pose,
  • Paula López-Roa,
  • Alba Ruedas-López,
  • Verónica Gonzalez-Galán,
  • Jaime Esteban,
  • Jorge Arca-Suárez,
  • Martín Pampín and
  • Alejandro Beceiro
  • + 3 authors

Background and Objectives: Infections caused by non-tuberculous mycobacteria (NTM), including Mycobacterium abscessus complex (MABc), are increasing globally and are notoriously difficult to treat due to the intrinsic resistance of these bacteria to...

  • Article
  • Open Access
3,092 Views
10 Pages

Clinical Outcomes of Escherichia coli Acute Bacterial Prostatitis: A Comparative Study of Oral Sequential Therapy with β-Lactam Versus Quinolone Antibiotics

  • Laura Gisbert,
  • Beatriz Dietl,
  • Mariona Xercavins,
  • Aina Mateu,
  • María López,
  • Ana Martínez-Urrea,
  • Lucía Boix-Palop and
  • Esther Calbo

Background/Objectives: Optimal management of acute bacterial prostatitis (ABP) remains uncertain, but the use of antibiotics with good prostatic tissue penetration is critical to prevent recurrence and chronic progression. This study aimed to describ...

  • Article
  • Open Access
5,161 Views
14 Pages

First-Line Prescriptions and Effectiveness of Helicobacter pylori Eradication Treatment in Ireland over a 10-Year Period: Data from the European Registry on Helicobacter pylori Management (Hp-EuReg)

  • Sinéad M. Smith,
  • Olga P. Nyssen,
  • Rebecca FitzGerald,
  • Thomas J. Butler,
  • Deirdre McNamara,
  • Asghar Qasim,
  • Conor Costigan,
  • Anna Cano-Catalá,
  • Pablo Parra and
  • Leticia Moreira
  • + 3 authors

Background: Local audits of Helicobacter pylori (H. pylori) prescriptions and outcomes are necessary to assess guideline awareness among clinicians and treatment effectiveness. Aims: The aims were to investigate first-line prescriptions and effective...

  • Article
  • Open Access
3 Citations
2,072 Views
19 Pages

Microbial Profile and Antibiotic Resistance Patterns in Bile Aspirates from Patients with Acute Cholangitis: A Multicenter International Study

  • Matei-Alexandru Cozma,
  • Mihnea-Alexandru Găman,
  • Camelia Cristina Diaconu,
  • Arthur Berger,
  • Frank Zerbib and
  • Radu Bogdan Mateescu

Objectives: Significant differences in antibiotic resistance (AR) rates and multi-drug resistant (MDR) bacteria incidence exist in patients with acute cholangitis (AC) from different countries or regions. We aim to characterize and compare the microb...

  • Article
  • Open Access
986 Views
18 Pages

Background/Objectives: Clostridioides difficile is a “One Health” pathogen and a cause of antibiotics-associated diarrhea and pseudomembranous colitis. Mobile genetic elements (MGEs) have been documented in the genomes of clinical C. diff...

  • Review
  • Open Access
5 Citations
4,428 Views
29 Pages

Antimicrobial and Antioxidant Activity of Essential Oils from Selected Pinus Species from Bosnia and Herzegovina

  • Snježana Mirković,
  • Milica Martinović,
  • Vanja M. Tadić,
  • Ivana Nešić,
  • Aleksandra Stolić Jovanović and
  • Ana Žugić

Essential oils are lipophilic secondary metabolites produced in various parts of aromatic plants and stored in specialized secretory structures. They play a vital role in plant defense, offering protection against microorganisms and herbivores. These...

  • Article
  • Open Access
1 Citations
2,888 Views
8 Pages

Antibiotic Prescription in Dentistry: Trends, Patient Demographics, and Drug Preferences in Germany

  • Lisa Lotta Cirkel,
  • Jens Martin Herrmann,
  • Claudia Ringel,
  • Bernd Wöstmann and
  • Karel Kostev

Background and objectives: ABs are widely used in dental practice in the treatment of odontogenic infections and as systemic prophylaxis in high-risk patients. However, AB overuse contributes to antimicrobial resistance (AMR), which is a major global...

  • Communication
  • Open Access
3,057 Views
9 Pages

Antimicrobial Susceptibility Testing of the Combination of Aztreonam and Avibactam in NDM-Producing Enterobacterales: A Comparative Evaluation Using the CLSI and EUCAST Methods

  • Linda Mei-Wah Chan,
  • Doris Yui Ling Lok,
  • River Chun Wai Wong,
  • Alfred Lok-Hang Lee,
  • Ingrid Yu-Ying Cheung,
  • Christopher Koon-Chi Lai and
  • Viola C. Y. Chow

Background: The combination of aztreonam (ATM) and avibactam (AVI) presents an important therapeutic option for carbapenem-resistant Enterobacterales, particularly the NDM-producing Enterobacterales. In 2024, both the CLSI and EUCAST published their...

  • Review
  • Open Access
10 Citations
2,716 Views
14 Pages

Postbiotics are defined as non-viable metabolites or compounds produced by probiotic microorganisms with significant impact on human health. The growing interest in postbiotics is supported by numerous studies due to their additional benefits over pr...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Antibiotics - ISSN 2079-6382