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Antibiotics, Volume 14, Issue 3

March 2025 - 115 articles

Cover Story: Exploring antimicrobial resistance (AMR) variation in Escherichia coli (E. coli) has often been conducted in the hospital setting, studying variation across large geographical regions or extended time periods. However, E. coli is a common cause of urinary tract infections in community settings, where environmental and agricultural factors influence its resistance patterns. Geo-temporal analysis offers the unique opportunity to explore AMR across these geographical and temporal contexts. This study analyzed the geo-temporal variation in the AMR of E. coli urinary isolates from 61,662 isolates over ten years, covering 90% of a community region. This study provides significant insights into the dynamic AMR landscape in the smaller community setting, emphasizing the need for community-specific surveillance. View this paper
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Articles (115)

  • Reply
  • Open Access
599 Views
2 Pages
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Reply to Canceill et al. Analyzing the Clinical Potential of Cold Atmospheric Plasma in Dentistry as an Alternative to Antibiotic Therapy. Comment on “Gross et al. Guided Plasma Application in Dentistry—An Alternative to Antibiotic Therapy. Antibiotics 2024, 13, 735”

  • Tara Gross,
  • Loic Alain Ledernez,
  • Laurent Birrer,
  • Michael Eckhard Bergmann and
  • Markus Jörg Altenburger
Antibiotics2025, 14(3), 327;https://doi.org/10.3390/antibiotics14030327

20 March 2025

Thank you for your interest and your thoughtful comment on our paper “Guided Plasma Application in Dentistry—An Alternative to Antibiotic Therapy” [...]

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  • Open Access
1 Citations
928 Views
14 Pages
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Unfavorable Outcomes and Their Risk Factors in Hospitalized Patients with Staphylococcus aureus Bacteremia in the US: A Multicenter Retrospective Cohort Study, 2020–2022

  • Marya D. Zilberberg,
  • Brian H. Nathanson,
  • Rolf Wagenaar,
  • Jan Posthumus and
  • Andrew F. Shorr
Antibiotics2025, 14(3), 326;https://doi.org/10.3390/antibiotics14030326

20 March 2025

Background: In the US, 120,000 cases of Staphylococcus aureus bacteremia (SAB) occur annually. Apart from mortality, little is known about other unfavorable outcomes (UOs). We developed a multifaceted definition for UOs in SAB and examined their inci...

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  • Open Access
1,303 Views
15 Pages
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Effects of Anti-Pseudomonal Agents, Individually and in Combination, With or Without Clarithromycin, on Growth and Biofilm Formation by Antibiotic-Susceptible and -Resistant Strains of Pseudomonas aeruginosa, and the Impact of Exposure to Cigarette Smoke Condensate

  • Moloko C. Cholo,
  • Charles Feldman,
  • Ronald Anderson,
  • Lebogang Sekalo,
  • Naledi Moloko and
  • Guy A. Richards
Antibiotics2025, 14(3), 325;https://doi.org/10.3390/antibiotics14030325

19 March 2025

Background/Objectives: Pseudomonas aeruginosa (Psa) can circumvent antimicrobial chemotherapy, an ability enhanced by cigarette smoking (CS). This study probed potential benefits of combinations of anti-pseudomonal agents, and potential augmenta...

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  • Open Access
3 Citations
1,424 Views
22 Pages
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Tackling Antimicrobial Resistance: A Sustainable Method for the Removal of Antibiotics from Water

  • Lekan Abudu,
  • Rutuja C. Bhosale,
  • Joerg Arnscheidt,
  • Svetlana Tretsiakova-McNally,
  • Barry O’Hagan,
  • David K. Adeyemi,
  • Temilola Oluseyi,
  • Luqman A. Adams and
  • Heather M. Coleman
Antibiotics2025, 14(3), 324;https://doi.org/10.3390/antibiotics14030324

19 March 2025

Introduction: The presence of antibiotic residues in the aquatic environment is a likely contributor to the current increase in antibiotic resistance, posing a significant threat to global health. This study investigated the use of a low-cost and sus...

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  • Open Access
1,196 Views
18 Pages
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Whole Genome Analysis of Pediococcus acidilactici XJ-24 and Its Role in Preventing Listeria monocytogenes ATCC® 19115TM Infection in C57BL/6 Mice

  • Weizhong Hu,
  • Shuxin Zhou,
  • Amel Ibrahim,
  • Guannan Li,
  • Sameh Awad,
  • José Ramos-Vivas,
  • Jianquan Kan and
  • Muying Du
Antibiotics2025, 14(3), 323;https://doi.org/10.3390/antibiotics14030323

19 March 2025

Background/Objectives: As probiotics gain prominence in the prevention and treatment of intestinal diseases, their protective effects against pathogens and influence on host health have drawn significant attention. This study investigates the genomic...

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  • Open Access
3,377 Views
18 Pages
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Antimicrobial Resistance and Mortality in Carbapenem-Resistant Pseudomonas aeruginosa Infections in Southern Thailand

  • Parichart Chotimakorn,
  • Sutthiporn Pattharachayakul,
  • Yongyut Lertsrisatit,
  • Wichai Santimaleeworagun,
  • Pimpimon Tansakul,
  • Mingkwan Yingkajorn,
  • Sureerat Chelae,
  • Rattanaruji Pomwised,
  • Arnon Chukamnerd and
  • Rosesathorn Soontarach
  • + 1 author
Antibiotics2025, 14(3), 322;https://doi.org/10.3390/antibiotics14030322

19 March 2025

Background/Objectives: Carbapenem-resistant Pseudomonas aeruginosa (CRPA) is an important pathogen associated with high mortality and treatment failure rates. We aimed to assess the susceptibility of CRPA to antipseudomonal agents, identify its resis...

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  • Open Access
1,296 Views
19 Pages
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Antiparasitic and Antifungal Activities of Cetyl-Maritima, a New N-Cetyl-Modified Maritima Derivative

  • Ibrahim S. Al Nasr,
  • Jingyi Ma,
  • Tariq A. Khan,
  • Waleed S. Koko,
  • Imen Ben Abdelmalek,
  • Rainer Schobert,
  • Wendy van de Sande and
  • Bernhard Biersack
Antibiotics2025, 14(3), 321;https://doi.org/10.3390/antibiotics14030321

19 March 2025

Background/Objectives: New drugs are urgently needed for the treatment of neglected tropical diseases including leishmaniasis and eumycetoma, as well as globally occurring parasitic diseases such as toxoplasmosis. Fragrances, both natural and synthet...

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  • Open Access
1,405 Views
11 Pages
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Evaluating Tuberculosis and Drug Resistance in Serbia: A Ten-Year Experience from a Tertiary Center

  • Mihailo Stjepanovic,
  • Snjezana Mijatovic,
  • Nikola Nikolic,
  • Nikola Maric,
  • Goran Stevanovic,
  • Ivan Soldatovic and
  • Aleksandra Barac
Antibiotics2025, 14(3), 320;https://doi.org/10.3390/antibiotics14030320

18 March 2025

Background: Tuberculosis (TB) remains a leading cause of mortality worldwide, particularly in low- and middle-income countries. The rise of multidrug-resistant TB (MDR-TB) poses significant challenges to global health. This study reviews the experien...

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  • Open Access
2,470 Views
12 Pages
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An Outbreak of Serratia marcescens in a Cardiothoracic Surgery Unit Associated with an Infected Solution of Pre-Prepared Syringes

  • Maria Papagianni,
  • Eleni Mylona,
  • Sofia Kostourou,
  • Chrysoula Kolokotroni,
  • Dimitris Kounatidis,
  • Natalia G. Vallianou and
  • Vasileios Papastamopoulos
Antibiotics2025, 14(3), 319;https://doi.org/10.3390/antibiotics14030319

18 March 2025

Background/Objectives: The aim of the present study is to report an outbreak of bloodstream infections caused by Serratia marcescens in patients undergoing postoperational procedures in the Cardiothoracic Department and to describe the epidemiologica...

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  • Article
  • Open Access
7 Citations
2,454 Views
20 Pages
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Postbiotic-Based Extracts from Native Probiotic Strains: A Promising Strategy for Food Preservation and Antimicrobial Defense

  • Diana Molina,
  • Ioana C. Marinas,
  • Evelyn Angamarca,
  • Anamaria Hanganu,
  • Miruna Stan,
  • Mariana C. Chifiriuc and
  • Gabriela N. Tenea
Antibiotics2025, 14(3), 318;https://doi.org/10.3390/antibiotics14030318

18 March 2025

Background/Objectives: The deterioration of food quality and safety is often linked to the presence of pathogenic and spoilage microorganisms. Postbiotics, including organic acids, enzymes, and bacteriocins produced by lactic acid bacteria (LAB), hav...

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