You are currently viewing a new version of our website. To view the old version click .

Antibiotics, Volume 12, Issue 3

March 2023 - 206 articles

Cover Story: Escherichia coli resistant to extended-spectrum cephalosporins (ESC-EC) are a major antimicrobial resistance threat. Furthermore, since they typically carry highly mobile plasmid-borne resistance genes and now have a global distribution in animal, human, and environmental sources, the highly complex epidemiology of ESC-EC infection requires a One Health approach to effectively design control and preventive measures. Here, we present the steps taken to assemble a database with phenotypic and genetic information on 10,763 ESC-EC isolates from multiple sources (humans, livestock, companion animals, wildlife, and environmental) in eight European countries under the framework of the DiSCoVeR Joint Research Project funded by the One Health European Joint Programme (OH-EJP), along with its strengths and limitations. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (206)

  • Case Report
  • Open Access
9 Citations
5,500 Views
9 Pages

Mycobacterium marinum: A Challenging Cause of Protracted Tenosynovitis

  • Pernille Grand Moestrup,
  • Maiken Stilling,
  • Christian Morberg Wejse and
  • Victor Naestholt Dahl

Mycobacterium marinum infections are rare, and they can be difficult to diagnose and treat. This may lead to further spread of the infection and complications, such as tenosynovitis, pyomyositis, and osteomyelitis. A 40-year-old previously healthy ma...

  • Review
  • Open Access
89 Citations
16,207 Views
62 Pages

The necessity for the discovery of innovative antimicrobials to treat life-threatening diseases has increased as multidrug-resistant bacteria has spread. Due to antibiotics’ availability over the counter in many nations, antibiotic resistance i...

  • Article
  • Open Access
8 Citations
2,812 Views
15 Pages

Artificial Neural Network Prediction of Antiadhesion and Antibiofilm-Forming Effects of Antimicrobial Active Mushroom Extracts on Food-Borne Pathogens

  • Jovana Vunduk,
  • Anita Klaus,
  • Vesna Lazić,
  • Maja Kozarski,
  • Danka Radić,
  • Olja Šovljanski and
  • Lato Pezo

The problem of microbial biofilms has come to the fore alongside food, pharmaceutical, and healthcare industrialization. The development of new antibiofilm products has become urgent, but it includes bioprospecting and is time and money-consuming. Co...

  • Article
  • Open Access
14 Citations
3,735 Views
13 Pages

Evaluation of Efflux-Mediated Resistance and Biofilm formation in Virulent Pseudomonas aeruginosa Associated with Healthcare Infections

  • Paul A. Akinduti,
  • Onome W. George,
  • Hannah U. Ohore,
  • Olusegun E. Ariyo,
  • Samuel T. Popoola,
  • Adenike I. Adeleye,
  • Kazeem S. Akinwande,
  • Jacob O. Popoola,
  • Solomon O. Rotimi and
  • Fredrick O. Olufemi
  • + 2 authors

Pseudomonas aeruginosa is a significant pathogen identified with healthcare-associated infections. The present study evaluates the role of biofilm and efflux pump activities in influencing high-level resistance in virulent P. aeruginosa strains in cl...

  • Review
  • Open Access
18 Citations
5,530 Views
36 Pages

A Comprehensive Review on Chemical Synthesis and Chemotherapeutic Potential of 3-Heteroaryl Fluoroquinolone Hybrids

  • Halyna Hryhoriv,
  • Sergiy M. Kovalenko,
  • Marine Georgiyants,
  • Lyudmila Sidorenko and
  • Victoriya Georgiyants

Fluoroquinolones have been studied for more than half a century. Since the 1960s, four generations of these synthetic antibiotics have been created and successfully introduced into clinical practice. However, they are still of interest for medicinal...

  • Article
  • Open Access
7 Citations
4,265 Views
16 Pages

Reporting Antimicrobial-Related Adverse Drug Events in Jordan: An Analysis from the VigiBase Database

  • Nizar Mahmoud Mhaidat,
  • Sayer Al-Azzam,
  • Hayaa Abdallah Banat,
  • Jaber Mohammad Jaber,
  • Mohammad Araydah,
  • Osama Y. Alshogran and
  • Mamoon A. Aldeyab

This study aims to assess the reporting of antimicrobial-related adverse drug events (ADEs) in Jordan between 2003 and 2022. Data regarding the antimicrobial-related ADEs were extracted from the WHO’s global database (VigiBase) by the Rational...

  • Article
  • Open Access
15 Citations
4,368 Views
13 Pages

The Antimicrobial Peptide Octopromycin Suppresses Biofilm Formation and Quorum Sensing in Acinetobacter baumannii

  • Dinusha Chathurangi Rajapaksha,
  • Shan Lakmal Edirisinghe,
  • Chamilani Nikapitiya,
  • Ilson Whang and
  • Mahanama De Zoysa

Acinetobacter baumannii is an opportunistic bacterial pathogen that causes severe infections in immunocompromised individuals. A. baumannii forms biofilm and produces extracellular matrix, which supports bacteria to survive under harsh conditions and...

  • Article
  • Open Access
5 Citations
3,032 Views
16 Pages

Vernonia polyanthes Less. (Asteraceae Bercht. & Presl), a Natural Source of Bioactive Compounds with Antibiotic Effect against Multidrug-Resistant Staphylococcus aureus

  • Jordana Damasceno Gitirana de Santana,
  • Oscar Alejandro Santos-Mayorga,
  • Jônatas Rodrigues Florencio,
  • Mirella Chrispim Cerqueira de Oliveira,
  • Luísa Maria Silveira de Almeida,
  • Julianna Oliveira de Lucas Xavier,
  • Danielle Cristina Zimmermann-Franco,
  • Gilson Costa Macedo,
  • Adriana Lúcia Pires Ferreira and
  • Orlando Vieira de Sousa
  • + 2 authors

Vernonia polyanthes is a medicinal plant used to treat many disorders, including infectious diseases. This study investigated the chemical constituents and the antibacterial activity of V. polyanthes leaf rinse extract (Vp-LRE). The chemical characte...

  • Article
  • Open Access
2 Citations
2,061 Views
11 Pages

Vancomycin Sequestration in ST Filters: An In Vitro Study

  • Frédéric J. Baud,
  • Pascal Houzé,
  • Jean-Herlé Raphalen,
  • Pascal Philippe and
  • Lionel Lamhaut

Background. Sequestration of vancomycin in ST® filters used in continuous renal therapy is a pending question. Direct vancomycin-ST® interaction was assessed using the in vitro NeckEpur® technology. Method. ST150® filter and Prismafle...

  • Article
  • Open Access
8 Citations
3,251 Views
15 Pages

Risk Factors, Genetic Diversity, and Antimicrobial Resistance of Staphylococcus spp. Isolates in Dogs Admitted to an Intensive Care Unit of a Veterinary Hospital

  • Jordana Almeida Santana,
  • Amanda Oliveira Paraguassu,
  • Ranielle Stephanie Toledo Santana,
  • Rafael Gariglio Clark Xavier,
  • Patricia Maria Colleto Freitas,
  • Flavia Figueira Aburjaile,
  • Vasco Ariston de Carvalho Azevedo,
  • Bertram Brenig,
  • Anders Miki Bojesen and
  • Rodrigo Otávio Silveira Silva

Intensive Care Units (ICU) usually provide an excellent environment for the selection of pathogens associated with hospital-acquired infections (HAI), leading to increased mortality and hospitalization costs. Methicillin-resistant Staphylococcus pseu...

of 21

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Antibiotics - ISSN 2079-6382