Table of Contents
Biosensors, Volume 10, Issue 4 (April 2020) – 14 articles
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Cover Story (view full-size image) Flexible screen-printed immunosensors, coated with single-walled carbon nanotubes (SWCNTs), were [...] Read more. Flexible screen-printed immunosensors, coated with single-walled carbon nanotubes (SWCNTs), were developed for the detection of histamine in fish samples based on a competitive assay. The immobilization of antihistamine antibodies on oxygen plasma treated SWCNTs led to highly selective (less than 3% relative response for cadaverine, putrescine, and tyramine) and sensitive histamine detection in a range as broad as 0.005 to 50 ng/mL, with a calculated limit of detection down to 2.48 pg/mL. The immunosensor response was well maintained even after 1000 bending cycles down to a radius of 4.4 mm, demonstrating great stability of the sensors against mechanical deformations. The analytical performance of the immunosensor was confirmed by detecting histamine in a complex real-fish-samples matrix, showing average recoveries from 96.0% to 104.7%.View this paper.