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Biosensors, Volume 10, Issue 3

2020 March - 15 articles

Cover Story: Molecularly-imprinted polymer nanoparticles (NanoMIPs), fabricated using solid phase synthesis, were combined with electrochemical impedance spectroscopy (EIS) to develop an affinity sensor for cocaine detection. The nanosensor was able to identify cocaine at trace concentrations (~0.24 ng mL-1) with high specificity and discriminate it from both morphine and one of the most common cutting agents, levamisole. Overall, the sensor can provide onsite, fast, and accurate results and therefore can be considered a valid alternative to sniffer dogs and to the onsite screening methods currently in use to identify cocaine in environmental samples.View this paper.
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Articles (15)

  • Communication
  • Open Access
15 Citations
6,879 Views
10 Pages

23 March 2020

Fluorescent proteins exhibit fluorescence quenching by specific transition metals, suggesting their potential as fluorescent protein-based metal biosensors. Each fluorescent protein exhibits unique spectroscopic properties and mechanisms for fluoresc...

  • Article
  • Open Access
4 Citations
6,224 Views
23 Pages

AC and DC Differential Bridge Structure Suitable for Electrochemical Interfacial Capacitance Biosensing Applications

  • Sara Neshani,
  • Charles K. A. Nyamekye,
  • Scott Melvin,
  • Emily A. Smith,
  • Degang J. Chen and
  • Nathan M. Neihart

22 March 2020

This paper presents a capacitive differential bridge structure with both AC and DC excitation and balancing capability for low cost electrode-solution interfacial capacitance biosensing applications. The proposed series RC balancing structure offers...

  • Article
  • Open Access
26 Citations
6,633 Views
9 Pages

Graphene Oxide Bulk-Modified Screen-Printed Electrodes Provide Beneficial Electroanalytical Sensing Capabilities

  • Samuel J. Rowley-Neale,
  • Dale A. C. Brownson,
  • Graham Smith and
  • Craig E. Banks

19 March 2020

We demonstrate a facile methodology for the mass production of graphene oxide (GO) bulk-modified screen-printed electrodes (GO-SPEs) that are economical, highly reproducible and provide analytically useful outputs. Through fabricating GO-SPEs with va...

(This article belongs to the Special Issue Dedication to Professor Agustín Costa-García: Screen-Printed Electrodes-Based (Bio)sensors: Development and New Challenges of the 21st Century)
  • Review
  • Open Access
54 Citations
12,566 Views
22 Pages

17 March 2020

The olfactory receptor neurons of insects and vertebrates are gated by odorant receptor (OR) proteins of which several members have been shown to exhibit remarkable sensitivity and selectivity towards volatile organic compounds of significant importa...

  • Article
  • Open Access
35 Citations
6,965 Views
15 Pages

Recyclable SERS-Based Immunoassay Guided by Photocatalytic Performance of Fe3O4@TiO2@Au Nanocomposites

  • Yuanyuan Du,
  • Hongmei Liu,
  • Yiran Tian,
  • Chenjie Gu,
  • Ziqi Zhao,
  • Shuwen Zeng and
  • Tao Jiang

16 March 2020

A novel recyclable surface-enhanced Raman scattering (SERS)-based immunoassay was demonstrated and exhibited extremely high sensitivity toward prostate specific antigen (PSA). The immunoassay, which possessed a sandwich structure, was constructed of...

  • Article
  • Open Access
42 Citations
7,932 Views
12 Pages

14 March 2020

In this article, a highly sensitive label-free immunosensor based on a graphene oxide (GO)/Fe3O4/Prussian blue (PB) nanocomposite modified electrode was developed for the determination of human hepatitis B surface antigen (HBsAg). In this electrochem...

  • Article
  • Open Access
19 Citations
5,940 Views
16 Pages

11 March 2020

In this paper, an electrochemical technique is introduced for the determination of streptomycin (STR) in the presence of oxytetracycline (OTC) in milk samples. A novel bifunctional modified screen-printed electrode (SPE) modified with oracet blue, si...

  • Article
  • Open Access
59 Citations
11,936 Views
13 Pages

Molecularly Imprinted Nanoparticles Based Sensor for Cocaine Detection

  • Roberta D’Aurelio,
  • Iva Chianella,
  • Jack A. Goode and
  • Ibtisam E. Tothill

4 March 2020

The development of a sensor based on molecularly imprinted polymer nanoparticles (nanoMIPs) and electrochemical impedance spectroscopy (EIS) for the detection of trace levels of cocaine is described in this paper. NanoMIPs for cocaine detection, synt...

(This article belongs to the Section Biosensor Materials)
  • Article
  • Open Access
17 Citations
5,723 Views
9 Pages

Surface Probe Linker with Tandem Anti-Fouling Properties for Application in Biosensor Technology

  • Sandro Spagnolo,
  • Brian De La Franier,
  • Tibor Hianik and
  • Michael Thompson

3 March 2020

This paper describes the anti-fouling capability of the novel monolayer-forming surface linker 3-(3-(trichlorosilylpropyloxy) propanoyl chloride (MEG-Cl). This compound was successfully attached to quartz crystal surfaces which are employed in an ele...

  • Review
  • Open Access
22 Citations
7,663 Views
38 Pages

3 March 2020

The presence of antimicrobial residues in food-producing animals can lead to harmful effects on the consumer (e.g., allergies, antimicrobial resistance, toxicological effects) and cause issues in food transformation (i.e., cheese, yogurts production)...

  • Article
  • Open Access
18 Citations
7,266 Views
14 Pages

A Disposable Passive Microfluidic Device for Cell Culturing

  • Francesco Guzzi,
  • Patrizio Candeloro,
  • Maria Laura Coluccio,
  • Costanza Maria Cristiani,
  • Elvira Immacolata Parrotta,
  • Luana Scaramuzzino,
  • Stefania Scalise,
  • Elisabetta Dattola,
  • Maria Antonia D’Attimo and
  • Gerardo Perozziello
  • + 6 authors

29 February 2020

In this work, a disposable passive microfluidic device for cell culturing that does not require any additional/external pressure sources is introduced. By regulating the height of fluidic columns and the aperture and closure of the source wells, the...

  • Article
  • Open Access
31 Citations
8,298 Views
9 Pages

The Detection of Wound Infection by Ion Mobility Chemical Analysis

  • Emma Daulton,
  • Alfian Wicaksono,
  • Janak Bechar,
  • James A. Covington and
  • Joseph Hardwicke

29 February 2020

Surgical site infection represents a large burden of care in the National Health Service. Current methods for diagnosis include a subjective clinical assessment and wound swab culture that may take several days to return a result. Both techniques are...

(This article belongs to the Special Issue Noninvasive Early Disease Diagnosis)
  • Article
  • Open Access
23 Citations
6,897 Views
11 Pages

Self-assembly Synthesis of Molecularly Imprinted Polymers for the Ultrasensitive Electrochemical Determination of Testosterone

  • Kai-Hsi Liu,
  • Danny O’Hare,
  • James L. Thomas,
  • Han-Zhang Guo,
  • Chien-Hsin Yang and
  • Mei-Hwa Lee

27 February 2020

Molecularly imprinted polymers (MIPs) can often bind target molecules with high selectivity and specificity. When used as MIPs, conductive polymers may have unique binding capabilities; they often contain aromatic rings and functional groups, which c...

  • Article
  • Open Access
32 Citations
11,082 Views
10 Pages

Design of Multiplex Lateral Flow Tests: A Case Study for Simultaneous Detection of Three Antibiotics

  • Anastasiya V. Bartosh,
  • Dmitriy V. Sotnikov,
  • Olga D. Hendrickson,
  • Anatoly V. Zherdev and
  • Boris B. Dzantiev

27 February 2020

The presented study is focused on the impact of binding zone location on immunochromatographic test strips on the analytical parameters of multiplex lateral flow assays. Due to non-equilibrium conditions for such assays the duration of immune reactio...

  • Review
  • Open Access
119 Citations
25,397 Views
16 Pages

Food Sensing: Detection of Bacillus cereus Spores in Dairy Products

  • Jasmina Vidic,
  • Carole Chaix,
  • Marisa Manzano and
  • Marc Heyndrickx

25 February 2020

Milk is a source of essential nutrients for infants and adults, and its production has increased worldwide over the past years. Despite developments in the dairy industry, premature spoilage of milk due to the contamination by Bacillus cereus continu...

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Biosensors - ISSN 2079-6374