Next Article in Journal
A Label-Free Immunosensor Based on Graphene Oxide/Fe3O4/Prussian Blue Nanocomposites for the Electrochemical Determination of HBsAg
Previous Article in Journal
Molecularly Imprinted Nanoparticles Based Sensor for Cocaine Detection
Open AccessArticle

Simultaneous Determination of Streptomycin and Oxytetracycline Using a Oracet-Blue/Silver-Nanoparticle/Graphene-Oxide/Modified Screen-Printed Electrode

1
Department of Chemistry, Yasouj University, Yasouj 75918-74831, Iran
2
Department of Chemistry, University of Toronto, 80 St. George Street, Toronto, ON M5S 3H6, Canada
3
Institute of Biomaterials & Biomedical Engineering, University of Toronto, 164 College Street, Toronto, ON M5S 3G9, Canada
*
Author to whom correspondence should be addressed.
Biosensors 2020, 10(3), 23; https://doi.org/10.3390/bios10030023
Received: 5 February 2020 / Revised: 2 March 2020 / Accepted: 6 March 2020 / Published: 11 March 2020
In this paper, an electrochemical technique is introduced for the determination of streptomycin (STR) in the presence of oxytetracycline (OTC) in milk samples. A novel bifunctional modified screen-printed electrode (SPE) modified with oracet blue, silver nanoparticles, and graphene oxide (OB/SNPs/GO/SPE) was fabricated. The modified electrode plays a catalyzer role for electrooxidation of STR at pH = 7.0 and reveals a facile a separation between the oxidation peaks of STR and OTC. Calculation of kinetic parameters such as the electron transfer coefficient α and the heterogeneous rate constant k´ of STR at the OB/SNPs/GO/SPE as 8.1 ± 0.07 cm s−1 and 0.32 have been obtained based on the theoretical model of Andrieux and Saveant. A differential pulse voltammetric measurement demonstrates two linear dynamic ranges, 0.4 to 240.0 nM and 240.0 to 720.0 nM and a detection limit of 0.17 nM for STR. The sensitivities of the OB/SNPs/GO/SPE towards the oxidation of STR in the absence and presence of OTC were 2.625 × 10−1 and 2.633 × 10−1 µA/µM, respectively. View Full-Text
Keywords: oracet blue; graphene oxide; streptomycin; oxytetracycline; screen-printed electrode oracet blue; graphene oxide; streptomycin; oxytetracycline; screen-printed electrode
Show Figures

Graphical abstract

MDPI and ACS Style

Akbarzadeh, S.; Khajesharifi, H.; Thompson, M. Simultaneous Determination of Streptomycin and Oxytetracycline Using a Oracet-Blue/Silver-Nanoparticle/Graphene-Oxide/Modified Screen-Printed Electrode. Biosensors 2020, 10, 23.

Show more citation formats Show less citations formats
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop