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Vaccines, Volume 13, Issue 2
February 2025 - 111 articles
Cover Story: The pursuit of an effective HIV-1 vaccine remains a key endeavor in the fight against HIV/AIDS. Despite decades of research, achieving an effective vaccine has proven to be elusive due to several challenges, including the virus's genetic variability, rapid mutation rates, host immune system evasion, and the establishment of latent reservoirs. This report explores the vital progress made in HIV-1 vaccine research, including strides in understanding the biology of the virus and the immune responses it elicits, informing the development of novel vaccine strategies. Furthermore, it addresses the ongoing challenges in each of these vaccine design endeavors. The paper also discusses the future directions and collaborative efforts needed to overcome these obstacles, emphasizing the importance of global cooperation in achieving a successful HIV-1 vaccine. View this paper
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