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Vaccines, Volume 11, Issue 8

2023 August - 116 articles

Cover Story: The two main types of studies used to assess seasonal influenza vaccine (SIV) performance are randomized controlled trials (RCTs) and observational studies, mainly, test negative designs (TNDs). RCTs are the gold standard for licensing of use, and TNDs are the main tool for monitoring the annual effectiveness of the SIV. In this paper, it was possible to compare the assessment of the trivalent inactivated vaccines by both designs. This is especially important as several papers adverts for the variety sources of bias that may affect TNDs. Although there are several systematic reviews addressing the performance of the SIV, none have yet addressed the reasons for different effectiveness estimates of the same SIV. It was found that a match between the vaccine and the most prevalent circulating strains and the laboratorial method for confirmation of influenza are important sources of bias. View this paper
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Articles (116)

  • Systematic Review
  • Open Access
12 Citations
3,576 Views
15 Pages

21 August 2023

Background: Multiple COVID-19 vaccines have been approved for use in adolescents; these vaccines play a critical role in limiting the transmission and impact of COVID-19. This systematic review aims to summarize the willingness of adolescents aged 10...

(This article belongs to the Special Issue Acceptance and Hesitancy in Vaccine Uptake)
  • Article
  • Open Access
15 Citations
3,935 Views
11 Pages

COPD-Related Mortality before and after Mass COVID-19 Vaccination in Northern Italy

  • Ugo Fedeli,
  • Veronica Casotto,
  • Claudio Barbiellini Amidei,
  • Andrea Vianello and
  • Gabriella Guarnieri

21 August 2023

Background/Objective: Little is known about the impact of the COVID-19 pandemic on mortality from COPD at the population level. The objective was to investigate COPD-related mortality throughout different epidemic waves in Italy before and after the...

(This article belongs to the Special Issue State of the art SARS-CoV-2 Research in Europe and Asia)
  • Review
  • Open Access
36 Citations
8,808 Views
13 Pages

Advances in Adjuvanted Influenza Vaccines

  • Shintaro Shichinohe and
  • Tokiko Watanabe

21 August 2023

The numerous influenza infections that occur every year present a major public health problem. Influenza vaccines are important for the prevention of the disease; however, their effectiveness against infection can be suboptimal. Particularly in the e...

(This article belongs to the Section Influenza Virus Vaccines)
  • Systematic Review
  • Open Access
8 Citations
3,624 Views
12 Pages

21 August 2023

Background: Routine human papillomavirus (HPV) vaccine uptake continues to be suboptimal since its recommendation in 2006 for girls and in 2011 for boys. This paper aims to review published quality improvement (QI) methodologies on interventions to i...

(This article belongs to the Section Vaccines and Public Health)
  • Review
  • Open Access
9 Citations
7,571 Views
17 Pages

Population-Level Risk Factors Related to Measles Case Fatality: A Conceptual Framework Based on Expert Consultation and Literature Review

  • Alyssa N. Sbarra,
  • Mark Jit,
  • Jonathan F. Mosser,
  • Matthew Ferrari and ,
  • Felicity Cutts,
  • Mark Papania,
  • Katrina Kretsinger,
  • Kevin A. McCarthy,
  • Niket Thakkar and
  • Allison Portnoy
  • + 10 authors+ 5 authors

21 August 2023

A better understanding of population-level factors related to measles case fatality is needed to estimate measles mortality burden and impact of interventions such as vaccination. This study aimed to develop a conceptual framework of mechanisms assoc...

(This article belongs to the Section Epidemiology and Vaccination)
  • Article
  • Open Access
6 Citations
2,940 Views
15 Pages

Are People Willing to Take Regular COVID-19 Vaccines? Prevalence and Determinants of Hesitancy for Regular COVID-19 Vaccination: A Random Population-Based Survey in Hong Kong

  • Yan Li,
  • Mengqi Li,
  • Lin Yang,
  • Daniel Bressington and ,
  • Sau-Fong Leung,
  • Yao-Jie Xie,
  • Jing Qin,
  • Alex Molasiotis and
  • Angela Y. M. Leung
  • + 4 authors+ 0 author

20 August 2023

The emergence of new coronavirus variants and evidence of waning immunity offered by COVID-19 vaccines draw attention to the need for regular vaccination. Vaccine hesitancy is one of the top ten threats to global health. There is a dearth of knowledg...

(This article belongs to the Section COVID-19 Vaccines and Vaccination)
  • Article
  • Open Access
4 Citations
2,632 Views
10 Pages

Sources of COVID-19 Vaccine Promotion for Pregnant and Lactating Women in Bangladesh

  • Berhaun Fesshaye,
  • Sydney A. Wade,
  • Clarice Lee,
  • Prachi Singh and ,
  • Eleonor Zavala,
  • Hasmot Ali,
  • Hafizur Rahman,
  • Towfida Jahan Siddiqua,
  • Shirina Atker and
  • Rupali J. Limaye
  • + 6 authors+ 1 author

20 August 2023

COVID-19 vaccines are an effective public health intervention to reduce COVID-19-related morbidity and mortality. Given that pregnant and lactating women have a higher risk of severe COVID-19 complications, it is paramount to understand the factors t...

(This article belongs to the Special Issue Trust, Willingness, and Associated Factors towards COVID-19 Vaccine Uptake)
  • Article
  • Open Access
25 Citations
5,464 Views
22 Pages

19 August 2023

In May 2023, the U.S. FDA advisors endorsed Pfizer’s pregnancy-administered vaccine (branded ABRYSVO) to protect infants from respiratory syncytial virus (RSV) infection. Vaccination can reduce the burden of RSV-related respiratory disease, wit...

(This article belongs to the Special Issue Vaccination Strategies as We Face Another Year of the COVID-19 Pandemic)
  • Article
  • Open Access
3 Citations
2,639 Views
19 Pages

Attitudes toward COVID-19 Vaccination: Staff and Patient Perspectives at Six Health Facilities in Sierra Leone

  • Stefanie A. Joseph,
  • Jean Gregory Jerome,
  • Foday Boima,
  • Pierre Ricard Pognon and ,
  • Donald Fejfar,
  • Yusupha Dibba,
  • Daniel Lavalie,
  • Mohamed Bailor Barrie,
  • Aramide Oteju and
  • Dale A. Barnhart
  • + 8 authors+ 3 authors

19 August 2023

Sierra Leone is a West African country with a population of over 8 million. With more than half of Sierra Leone’s population living in rural areas, it is important to understand rural populations’ access to and attitudes toward the COVID-...

(This article belongs to the Special Issue Attitudes and Perspectives toward COVID-19 Vaccines)
  • Article
  • Open Access
6 Citations
2,476 Views
18 Pages

19 August 2023

Control of the intracellular parasite Leishmania (L.) requires the activation of strong type 1 cellular immune responses. Towards this goal, in the present study, a multiepitope chimeric protein named LiChimera was encapsulated into cationic liposome...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
  • Article
  • Open Access
3 Citations
4,139 Views
12 Pages

Influenza Vaccination during Pregnancy: A Descriptive Study of the Knowledge, Beliefs, and Practices of Mexican Gynecologists and Family Physicians

  • Erika Zoe Lopatynsky-Reyes,
  • Enrique Chacon-Cruz,
  • Michael Greenberg,
  • Ralf Clemens and
  • Sue Ann Costa Clemens

19 August 2023

Background: Influenza in pregnancy is associated with elevated morbidity and mortality. Influenza vaccines are safe and effective in pregnancy. There are no Mexican surveys of physicians on knowledge, beliefs, and practices towards influenza and infl...

(This article belongs to the Special Issue SARS-CoV-2, Influenza and Other Respiratory Viruses: Epidemiology, Burden of Disease, and Preventive Measures)
  • Article
  • Open Access
8 Citations
3,222 Views
11 Pages

Impact of a COVID-19 Outbreak in an Elderly Care Home after Primary Vaccination

  • Elba Mauriz,
  • José P. Fernández-Vázquez,
  • Cristina Díez-Flecha,
  • Sofía Reguero-Celada and ,
  • Tania Fernández-Villa,
  • Ana Fernández-Somoano,
  • Joan A. Caylà,
  • Jesús A. Lozano-García,
  • Ana M. Vázquez-Casares and
  • Vicente Martín-Sánchez
  • + 5 authors+ 0 author

19 August 2023

Elderly care home residents are particularly vulnerable to COVID-19 due to immune-senescence, pre-existing medical conditions, and the risk of transmission from staff and visitors. This study aimed to describe the outcomes of a COVID-19 outbreak in a...

(This article belongs to the Special Issue COVID-19 and Vaccination Strategies in Global Health)
  • Article
  • Open Access
5 Citations
3,346 Views
23 Pages

Unveiling Vaccine Hesitancy on Twitter: Analyzing Trends and Reasons during the Emergence of COVID-19 Delta and Omicron Variants

  • Liviu-Adrian Cotfas,
  • Liliana Crăciun,
  • Camelia Delcea,
  • Margareta Stela Florescu and ,
  • Erik-Robert Kovacs,
  • Anca Gabriela Molănescu and
  • Mihai Orzan
  • + 2 authors+ 0 author

18 August 2023

Given the high amount of information available on social media, the paper explores the degree of vaccine hesitancy expressed in English tweets posted worldwide during two different one-month periods of time following the announcement regarding the di...

(This article belongs to the Section COVID-19 Vaccines and Vaccination)
  • Editorial
  • Open Access
1,545 Views
2 Pages

18 August 2023

Public health is aimed at protecting and promoting citizens’ and communities’ health through different interventions, including vaccinations [...]

(This article belongs to the Special Issue COVID-19 Vaccines: A Public Health Perspective)
  • Article
  • Open Access
8 Citations
2,759 Views
18 Pages

Hybrid Immunity Provides the Best COVID-19 Humoral Response in Immunocompromised Patients with or without SARS-CoV-2 Infection History

  • Paulina Nazaruk,
  • Ignacy Tkaczyk,
  • Marta Monticolo,
  • Anna Maria Jędrzejczak and ,
  • Natalia Krata,
  • Leszek Pączek,
  • Bartosz Foroncewicz and
  • Krzysztof Mucha
  • + 3 authors+ 0 author

18 August 2023

Immunization against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has significantly limited the spread of coronavirus disease 2019 (COVID-19) and reduced the associated complications, especially mortality. To prolong immunity, an immu...

(This article belongs to the Special Issue COVID-19 and Vaccination Strategies in Global Health)
  • Article
  • Open Access
8 Citations
3,444 Views
13 Pages

17 August 2023

The Public Health Agency of Canada recommends that 80% of high-risk persons, including adults aged ≥65 years and 18–64 years with certain comorbidities, be vaccinated against influenza. During the 2022–2023 influenza season, we conduct...

  • Article
  • Open Access
6 Citations
3,506 Views
11 Pages

Efficiency Comparative Approach of Plant-Produced Monoclonal Antibodies against Rabies Virus Infection

  • Boonlert Lumlertdacha,
  • Bancha Mahong,
  • Kaewta Rattanapisit,
  • Christine Joy I. Bulaon and ,
  • Thiravat Hemachudha and
  • Waranyoo Phoolcharoen
  • + 1 author+ 0 author

17 August 2023

Rabies encephalitis is a fatal zoonotic viral disease caused by the neurotropic rabies virus. It remains a major public health concern as it causes almost 100% fatality and has no effective medication after the onset of the disease. However, this ill...

(This article belongs to the Special Issue Rabies Vaccines and Immunoglobulins)
  • Article
  • Open Access
14 Citations
3,017 Views
15 Pages

A Comparative Study of Immunogenicity, Antibody Persistence, and Safety of Three Different COVID-19 Boosters between Individuals with Comorbidities and the Normal Population

  • Fatemeh Ashrafian,
  • Fahimeh Bagheri Amiri,
  • Anahita Bavand,
  • Mahsan Zali and ,
  • Mona Sadat Larijani and
  • Amitis Ramezani
  • + 1 author+ 0 author

17 August 2023

Data on immunogenicity, immune response persistency, and safety of COVID-19 boosters in patients with comorbidities are limited. Therefore, we aimed to evaluate three different boosters’ immunogenicity and safety in individuals with at least on...

(This article belongs to the Special Issue Antibody Response to Infection and Vaccination)
  • Article
  • Open Access
19 Citations
2,748 Views
13 Pages

Does Vaccine Confidence Mediate the Relationship between Vaccine Literacy and Influenza Vaccination? Exploring Determinants of Vaccination among Staff Members of Nursing Homes in Tuscany, Italy, during the COVID-19 Pandemic

  • Francesca Collini,
  • Guglielmo Bonaccorsi,
  • Marco Del Riccio,
  • Mario Bruschi and ,
  • Silvia Forni,
  • Giacomo Galletti,
  • Fabrizio Gemmi,
  • Francesca Ierardi and
  • Chiara Lorini
  • + 4 authors+ 0 author

17 August 2023

Background: Low coverage of influenza vaccination in nursing home (NH) staff may be attributed to factors such as vaccine confidence (VC) and vaccine literacy (VL). Our study aimed to evaluate the role of VL and VC in predicting the intention to get...

(This article belongs to the Special Issue Vaccine Literacy and Social–Cognitive Determinants of Vaccination)
  • Article
  • Open Access
3 Citations
2,300 Views
11 Pages

16 August 2023

Background: Evidence on SARS-CoV-2 mRNA vaccination under siponimod treatment is rare. Methods: AMA-VACC is a prospective, open-label clinical study on SARS-CoV-2 mRNA vaccination during ongoing siponimod treatment (cohort 1), during siponimod interr...

  • Article
  • Open Access
25 Citations
3,938 Views
19 Pages

VP4/VP56/VP35 Virus-like Particles Effectively Protect Grass Carp (Ctenopharyngodon idella) against GCRV-II Infection

  • Qingqing Tian,
  • Xingchen Huo,
  • Qian Liu,
  • Chunrong Yang and ,
  • Yongan Zhang and
  • Jianguo Su
  • + 1 author+ 0 author

16 August 2023

Grass carp reovirus (GCRV) seriously threatens the grass carp (Ctenopharyngodon idella) industry. Prophylactic GCRV vaccines prepared by virus-like particle (VLP) assembly biotechnology can improve effectiveness and safety. The highly immunogenic can...

(This article belongs to the Special Issue Fish Immunology, Vaccines and Novel Treatments)
  • Review
  • Open Access
18 Citations
3,883 Views
17 Pages

Plant Viruses as Adjuvants for Next-Generation Vaccines and Immunotherapy

  • Nikolai Nikitin,
  • Yuri Vasiliev,
  • Angelina Kovalenko,
  • Ekaterina Ryabchevskaya and ,
  • Olga Kondakova,
  • Ekaterina Evtushenko and
  • Olga Karpova
  • + 2 authors+ 0 author

16 August 2023

Vaccines are the cornerstone of infectious disease control and prevention. The outbreak of SARS-CoV-2 has confirmed the urgent need for a new approach to the design of novel vaccines. Plant viruses and their derivatives are being used increasingly fo...

(This article belongs to the Special Issue State-of-the-Art Vaccine Researches)
  • Article
  • Open Access
22 Citations
4,076 Views
12 Pages

National HPV Vaccination Program in Poland—Public Awareness, Sources of Knowledge, and Willingness to Vaccinate Children against HPV

  • Mateusz Jankowski,
  • Justyna Grudziąż-Sękowska,
  • Iwona Wrześniewska-Wal,
  • Piotr Tyszko and ,
  • Kuba Sękowski,
  • Janusz Ostrowski,
  • Mariusz Gujski and
  • Jarosław Pinkas
  • + 3 authors+ 0 author

16 August 2023

Since 1 June 2023, a nationwide HPV vaccination program was implemented in Poland. This study aimed to identify factors associated with public awareness of the national HPV vaccination program among adults in Poland and willingness to vaccinate child...

(This article belongs to the Special Issue Vaccination Progress in COVID-19 and HPV)
  • Article
  • Open Access
22 Citations
5,041 Views
12 Pages

Reasons for Being “Zero-Dose and Under-Vaccinated” among Children Aged 12–23 Months in the Democratic Republic of the Congo

  • Daniel Katuashi Ishoso,
  • Eric Mafuta,
  • M. Carolina Danovaro-Holliday,
  • Christian Ngandu and ,
  • Lisa Menning,
  • Aimé Mwana-Wabene Cikomola,
  • Christophe Luhata Lungayo,
  • Jean-Crispin Mukendi,
  • Dieudonné Mwamba and
  • Marcellin Mengouo Nimpa
  • + 16 authors+ 11 authors

16 August 2023

(1) Introduction: The Democratic Republic of the Congo (DRC) has one of the largest cohorts of un- and under-vaccinated children worldwide. This study aimed to identify and compare the main reasons for there being zero-dose (ZD) or under-vaccinated c...

  • Article
  • Open Access
25 Citations
4,131 Views
13 Pages

15 August 2023

In June 2010, Greece introduced the 13-valent pneumococcal conjugate vaccine (PCV13) for pediatric vaccination and has since observed a large decrease in pneumococcal disease caused by these vaccine serotypes, yet the disease prevalence of non-vaccin...

(This article belongs to the Section Vaccines Against Tropical and Other Infectious Diseases)
  • Article
  • Open Access
10 Citations
3,212 Views
18 Pages

Belarusian Healthcare Professionals’ Views on Monkeypox and Vaccine Hesitancy

  • Abanoub Riad,
  • Nadzeya Rybakova,
  • Nadzeya Dubatouka,
  • Ina Zankevich and ,
  • Miloslav Klugar,
  • Michal Koščík and
  • Anton Drobov
  • + 2 authors+ 0 author

15 August 2023

Background: Despite the low transmission risk of Monkeypox (mpox) in Belarus, this study is vital as it contributes to our understanding of vaccine hesitancy among healthcare professionals (HCPs). It aims to assess vaccination perceptions and evaluat...

(This article belongs to the Special Issue Recent Advances in Factors Associated with Vaccine Hesitancy and Acceptance)
  • Article
  • Open Access
27 Citations
4,296 Views
12 Pages

15 August 2023

Human papillomavirus (HPV) vaccination has been proven to be the most effective method to prevent cervical cancer. This study aimed to determine the HPV vaccination behavior and preference in Chinese female health care workers. A nationwide cross-sec...

  • Article
  • Open Access
6 Citations
2,803 Views
13 Pages

A Qualitative Study on Barriers to COVID-19 Vaccine Uptake among Community Members in Tanzania

  • Melina Bernard Mgongo,
  • Rachel N. Manongi,
  • Innocent B. Mboya,
  • James S. Ngocho and ,
  • Caroline Amour,
  • Monica Mtei,
  • Julieth S. Bilakwate,
  • Ahmed Yusuph Nyaki,
  • Johnston M. George and
  • Sia E. Msuya
  • + 13 authors+ 8 authors

15 August 2023

The use of vaccines is one of the key tools in reversing the COVID-19 pandemic; however, various reports reported the low uptake of the vaccines. This study explored the barriers to the COVID-19 vaccine uptake among community members in Tanzania. A q...

(This article belongs to the Special Issue Vaccines for COVID-19)
  • Review
  • Open Access
7 Citations
3,277 Views
13 Pages

Attitudes towards COVID Vaccine and Vaccine Hesitancy in Dermatology: A Narrative Review

  • Woo Chiao Tay,
  • Anthony Bewley,
  • Julia-Tatjana Maul and
  • Hazel H. Oon

15 August 2023

Vaccine hesitancy has been a contentious issue even before the pandemic. The COVID-19 crisis has further amplified vaccine hesitancy, with worries about adverse effects, cultural and religious beliefs, and misinformation on social media. In dermatolo...

(This article belongs to the Special Issue SARS-CoV-2 (COVID-19) Vaccination and Compliance/Hesitancy)
  • Article
  • Open Access
3 Citations
5,990 Views
13 Pages

Development of an Enhanced High-Yield Influenza Vaccine Backbone in Embryonated Chicken Eggs

  • Lizheng Guan,
  • Jihui Ping,
  • Tiago J. S. Lopes,
  • Shufang Fan and ,
  • Robert Presler,
  • Gabriele Neumann and
  • Yoshihiro Kawaoka
  • + 2 authors+ 0 author

15 August 2023

Vaccination is an efficient approach to preventing influenza virus infections. Recently, we developed influenza A and B virus vaccine backbones that increased the yield of several vaccine viruses in Madin–Darby canine kidney (MDCK) and African...

(This article belongs to the Section Influenza Virus Vaccines)
  • Article
  • Open Access
13 Citations
3,753 Views
19 Pages

Substitution of Coxsackievirus A16 VP1 BC and EF Loop Altered the Protective Immune Responses in Chimera Enterovirus A71

  • Xiu Hui Tan,
  • Wei Lim Chong,
  • Vannajan Sanghiran Lee,
  • Syahril Abdullah and ,
  • Kartini Jasni,
  • Saiful Qushairi Suarni,
  • David Perera,
  • I-Ching Sam and
  • Yoke Fun Chan
  • + 4 authors+ 0 author

14 August 2023

Hand, foot and mouth disease (HFMD) is a childhood disease caused by enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16). Capsid loops are important epitopes for EV-A71 and CV-A16. Seven chimeric EV-A71 (ChiE71) involving VP1 BC (45.5% similarit...

  • Article
  • Open Access
4 Citations
3,268 Views
12 Pages

14 August 2023

Herpes simplex viruses (HSV) cause chronic infections with significant morbidity. Prior vaccines, designed to generate neutralizing antibodies (nAbs) targeting glycoprotein D (gD), failed to provide durable protection. We adopted a different strategy...

(This article belongs to the Section Vaccine Design, Development, and Delivery)
  • Communication
  • Open Access
11 Citations
2,849 Views
8 Pages

How European Research Projects Can Support Vaccination Strategies: The Case of the ORCHESTRA Project for SARS-CoV-2

  • Anna Maria Azzini,
  • Lorenzo Maria Canziani,
  • Ruth Joanna Davis,
  • Massimo Mirandola and ,
  • Michael Hoelscher,
  • Laurence Meyer,
  • Cédric Laouénan,
  • Maddalena Giannella,
  • Jesús Rodríguez-Baño and
  • Evelina Tacconelli
  • + 12 authors+ 7 authors

14 August 2023

ORCHESTRA (“Connecting European Cohorts to Increase Common and Effective Response To SARS-CoV-2 Pandemic”) is an EU-funded project which aims to help rapidly advance the knowledge related to the prevention of the SARS-CoV-2 infection and...

(This article belongs to the Section COVID-19 Vaccines and Vaccination)
  • Systematic Review
  • Open Access
24 Citations
6,080 Views
31 Pages

Parental Acceptance, Parental Hesitancy, and Uptake of Seasonal Influenza Vaccination among Children Aged 6–59 Months: A Systematic Review and Meta-Analysis

  • Paul Shing-fong Chan,
  • Yuan Fang,
  • Joseph Kawuki,
  • Siyu Chen and ,
  • Xue Liang,
  • Phoenix Kit-han Mo and
  • Zixin Wang
  • + 2 authors+ 0 author

13 August 2023

This systematic review and meta-analysis summarises the literature on parental acceptance, parental hesitancy, uptake, and the associated factors of seasonal influenza vaccination (SIV) among children aged 6–59 months. Studies were sourced from...

  • Review
  • Open Access
10 Citations
4,927 Views
10 Pages

Changes in the Epidemiology of Rubella: The Influence of Vaccine-Introducing Methods and COVID-19

  • Naruhito Otani,
  • Masayuki Shima,
  • Takashi Ueda,
  • Kazuhiko Nakajima and ,
  • Yoshio Takesue,
  • Takuma Yamamoto and
  • Toshiomi Okuno
  • + 2 authors+ 0 author

12 August 2023

Rubella is an infectious disease caused by the rubella virus. Congenital rubella syndrome is a risk for all newborns if pregnant women are infected with rubella, raising an important public health issue. Rubella is a vaccine-preventable disease, and...

(This article belongs to the Special Issue Vaccines and Vaccinations in the Pandemic Period)
  • Article
  • Open Access
8 Citations
2,371 Views
13 Pages

Attitudes towards HPV Vaccination Policy Strategies to Improve Adolescent Vaccination Coverage among Pediatric Providers in New York State

  • Jana Shaw,
  • Samantha Hanley,
  • Elana Sitnik,
  • Winter Berry and ,
  • Steven Blatt,
  • Michael Seserman and
  • Margaret K. Formica
  • + 2 authors+ 0 author

12 August 2023

Pediatric providers’ stances on HPV vaccination-related policies are largely unknown. To gain insight into pediatric providers’ perspectives and potential recommendations for directed policy, we conducted a cross-sectional survey of the A...

(This article belongs to the Special Issue Focus on Human Papillomavirus Vaccines)
  • Review
  • Open Access
54 Citations
8,153 Views
16 Pages

A Comprehensive Review on Cancer Vaccines and Vaccine Strategies in Hepatocellular Carcinoma

  • Alireza Tojjari,
  • Ahmed Saeed,
  • Meghana Singh,
  • Ludimila Cavalcante and ,
  • Ibrahim Halil Sahin and
  • Anwaar Saeed
  • + 1 author+ 0 author

12 August 2023

HCC, the most prevalent form of primary liver cancer, presents a substantial global health challenge due to its high mortality and limited therapeutic options. This review delves into the potential of cancer vaccines as a novel therapeutic avenue for...

(This article belongs to the Special Issue Cancer Vaccines 3.0)
  • Review
  • Open Access
40 Citations
5,333 Views
16 Pages

Addressing Nanovaccine Strategies for Tilapia

  • Kim D. Thompson,
  • Channarong Rodkhum,
  • Anurak Bunnoy,
  • Patcharapong Thangsunan and ,
  • Sirikorn Kitiyodom,
  • Pimwarang Sukkarun,
  • Jakarwan Yostawornkul,
  • Teerapong Yata and
  • Nopadon Pirarat
  • + 4 authors+ 0 author

11 August 2023

Tilapia is the world’s most extensively farmed species after carp. It is an attractive species for aquaculture as it grows quickly, reaching harvest size within six to seven months of production, and provides an important source of food and rev...

(This article belongs to the Section Veterinary Vaccines)
  • Article
  • Open Access
10 Citations
3,787 Views
13 Pages

A Nationwide Digital Multidisciplinary Intervention Aimed at Promoting Pneumococcal Vaccination in Immunocompromised Patients

  • Shirley Shapiro Ben David,
  • Orna Shamai-Lubovitz,
  • Vered Mourad,
  • Iris Goren and ,
  • Erica Cohen Iunger,
  • Tamar Alcalay,
  • Angela Irony,
  • Shira Greenfeld,
  • Limor Adler and
  • Amos Cahan
  • + 5 authors+ 0 author

11 August 2023

Immunocompromised patients (IPs) are at high risk for infections, some of which are vaccine-preventable. The Israeli Ministry of Health recommends pneumococcal conjugate vaccine 13 (PCV13) and pneumococcal polysaccharide vaccine 23 (PPSV23) for IP, b...

(This article belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)
  • Review
  • Open Access
19 Citations
7,642 Views
26 Pages

Advancing Immunotherapies for HPV-Related Cancers: Exploring Novel Vaccine Strategies and the Influence of Tumor Microenvironment

  • Anna Jéssica Duarte Silva,
  • Ingrid Andrêssa de Moura,
  • Marco Antonio Turiah Machado da Gama,
  • Lígia Rosa Sales Leal and ,
  • Samara Sousa de Pinho,
  • Benigno Cristofer Flores Espinoza,
  • Daffany Luana dos Santos,
  • Vanessa Emanuelle Pereira Santos,
  • Matheus Gardini Amancio Marques De Sena and
  • Antonio Carlos de Freitas
  • + 8 authors+ 3 authors

11 August 2023

The understanding of the relationship between immunological responses and cancers, especially those related to HPV, has allowed for the study and development of therapeutic vaccines against these neoplasias. There is a growing number of studies about...

(This article belongs to the Special Issue Focus on Human Papillomavirus Vaccines)
  • Article
  • Open Access
3 Citations
2,284 Views
15 Pages

10 August 2023

Middle East respiratory syndrome coronavirus (MERS-CoV) causes severe diseases in humans. Camels act as intermediate hosts for MERS-CoV. Currently, no licensed vaccine is available for this virus. We have developed a potential candidate vaccine for M...

  • Article
  • Open Access
4 Citations
2,851 Views
17 Pages

Humoral Immune Response in Calves Vaccinated with Monovalent Vaccines or a Trivalent Combination Thereof and Matching of These Vaccines to the Selected Circulating Foot-and-Mouth Disease Viruses in Ethiopia

  • Fanos Tadesse Woldemariyam,
  • Demessa Negessu,
  • Tsion Bilata,
  • Ayelech Muluneh and ,
  • Dereje Shegu Gebreweld,
  • Ibsa Teshome Ebisa and
  • Jan Paeshuyse
  • + 2 authors+ 0 author

10 August 2023

Foot-and-mouth disease (FMD) is an endemic, highly contagious, and devastating disease of livestock production in Ethiopia. Control of this disease relies mainly on prophylactic vaccination by willing farmers without a countrywide vaccination program...

(This article belongs to the Special Issue Immune Response to the Vaccines against Foot-and-Mouth Disease and Other Similar Animal Diseases)
  • Article
  • Open Access
4 Citations
1,947 Views
12 Pages

9 August 2023

Socio-demographic factors are responsible for health inequalities also in vaccination. The aim of this study was to evaluate their role at the population level through a population-based study performed on the whole population entitled to receive COV...

(This article belongs to the Special Issue Factors Associated with COVID-19 Vaccination)
  • Article
  • Open Access
15 Citations
3,898 Views
18 Pages

COVID-19 Vaccine Acceptance and Hesitancy among Healthcare Workers in Lusaka, Zambia; Findings and Implications for the Future

  • Steward Mudenda,
  • Victor Daka,
  • Scott K. Matafwali,
  • Phumzile Skosana and ,
  • Billy Chabalenge,
  • Moses Mukosha,
  • Joseph O. Fadare,
  • Ruth L. Mfune,
  • Bwalya A. Witika and
  • Angela G. Bwalya
  • + 9 authors+ 4 authors

9 August 2023

The uptake of COVID-19 vaccines is critical to address the severe consequences of the disease. Previous studies have suggested that many healthcare workers (HCWs) are hesitant to receive the COVID-19 vaccine, further enhancing hesitancy rates within...

  • Article
  • Open Access
12 Citations
2,501 Views
14 Pages

Protective Efficacy of a Candidate Live-Attenuated Vaccine Derived from the SD-R Strain against NADC34-like Porcine Reproductive and Respiratory Syndrome Virus

  • Hu Xu,
  • Chao Li,
  • Bangjun Gong,
  • Wansheng Li and ,
  • Zhenyang Guo,
  • Qi Sun,
  • Jing Zhao,
  • Lirun Xiang,
  • Jinhao Li and
  • Hongliang Zhang
  • + 14 authors+ 9 authors

9 August 2023

NADC34-like porcine reproductive and respiratory syndrome virus (PRRSV) strains were first detected in China in 2017 and became major circulating strains in 2021. Our previous study showed that the live-attenuated vaccine candidate SD-R strain could...

(This article belongs to the Section Veterinary Vaccines)
  • Article
  • Open Access
2 Citations
3,575 Views
13 Pages

Cardiac Function Evaluation after SARS-CoV-2 mRNA Vaccination in Children and Adolescents: A Prospective Speckle-Tracking Echocardiography Study

  • Jolanda Sabatino,
  • Costanza Di Chiara,
  • Daria Lauretta,
  • Jennifer Fumanelli and ,
  • Greta Luana D’Ascoli,
  • Daniele Donà,
  • Sandra Cozzani,
  • Andrea Oletto,
  • Carlo Giaquinto and
  • Giovanni Di Salvo
  • + 5 authors+ 0 author

9 August 2023

Background: Possible cardiac impairment after SARS-CoV-2 mRNA vaccination is a common driver of parental vaccine hesitancy. We performed a comprehensive echocardiographic evaluation of biventricular function in vaccinated children with or without pre...

(This article belongs to the Special Issue Vaccines for COVID-19)
  • Review
  • Open Access
15 Citations
6,247 Views
35 Pages

Exigency of Plant-Based Vaccine against COVID-19 Emergence as Pandemic Preparedness

  • Anirudha Chattopadhyay,
  • A. Abdul Kader Jailani and
  • Bikash Mandal

9 August 2023

After two years since the declaration of COVID-19 as a pandemic by the World Health Organization (WHO), more than six million deaths have occurred due to SARS-CoV-2, leading to an unprecedented disruption of the global economy. Fortunately, within a...

(This article belongs to the Special Issue Plant-Produced Vaccines, Therapeutics and Phytochemicals: Recent Developments, Challenges and Perspectives)
  • Article
  • Open Access
11 Citations
3,905 Views
18 Pages

Assessing Brigada Digital de Salud Audience Reach and Engagement: A Digital Community Health Worker Model to Address COVID-19 Misinformation in Spanish on Social Media

  • Elizabeth L. Andrade,
  • Lorien C. Abroms,
  • Anna I. González,
  • Carla Favetto and ,
  • Valeria Gomez,
  • Manuel Díaz-Ramírez,
  • César Palacios and
  • Mark C. Edberg
  • + 3 authors+ 0 author

9 August 2023

U.S. Spanish-speaking populations experienced gaps in timely COVID-19 information during the pandemic and disproportionate misinformation exposure. Brigada Digital de Salud was established to address these gaps with culturally tailored, Spanish-langu...

(This article belongs to the Special Issue Challenges and Future Trends of COVID-19 Vaccination)
  • Review
  • Open Access
31 Citations
5,875 Views
14 Pages

Monkeypox Virus: A Comprehensive Overview of Viral Pathology, Immune Response, and Antiviral Strategies

  • Shiza Malik,
  • Amna Ahmed,
  • Omar Ahsan,
  • Khalid Muhammad and
  • Yasir Waheed

9 August 2023

Background: The years 2022–2023 witnessed a monkeypox virus (mpox) outbreak in some countries worldwide, where it exists in an endemic form. However, the number of infectious cases is continuously on the rise, and there has been an unexpected,...

(This article belongs to the Special Issue Vaccination for Monkeypox Infection in Humans)
  • Article
  • Open Access
3 Citations
3,157 Views
14 Pages

The Adjuvant Activity of BCG Cell Wall Cytoskeleton on a Dengue Virus-2 Subunit Vaccine

  • Tuksin Jearanaiwitayakul,
  • Saradee Warit,
  • Kritsadayut Lekjinda,
  • Mathurin Seesen and ,
  • Jitra Limthongkul,
  • Panuwat Midoeng,
  • Panya Sunintaboon and
  • Sukathida Ubol
  • + 3 authors+ 0 author

9 August 2023

The uneven immunogenicity of the attenuated tetravalent dengue vaccine has made it difficult to achieve balanced protection against all four serotypes of the dengue virus (DENV). To overcome this problem, non-replicative vaccines have come into focus...

(This article belongs to the Special Issue Vaccines against Flaviviruses and Alphaviruses: Recent Advances and Future Challenges)

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Vaccines - ISSN 2076-393X