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Antioxidants, Volume 6, Issue 2

June 2017 - 22 articles

Cover Story: The background shows a primary pneumocyte culture. In the center, there are two pictures representing a mitosis (upper left), a micronucleus (upper right), an apoptosis (lower left) and necrotic nuclei (lower right). On the right, the COMET assay is addressed showing a nucleoid with DNA fragments distributed in the tail. Furthermore, on the top of the cover, the structural formula of beta-carotin is given; on the bottom, three structures of volatile oxidative degradation products are shown. View this paper
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Articles (22)

  • Article
  • Open Access
64 Citations
8,802 Views
13 Pages

NOX2-Induced Activation of Arginase and Diabetes-Induced Retinal Endothelial Cell Senescence

  • Modesto Rojas,
  • Tahira Lemtalsi,
  • Haroldo A. Toque,
  • Zhimin Xu,
  • David Fulton,
  • Robert William Caldwell and
  • Ruth B. Caldwell

Increases in reactive oxygen species (ROS) and decreases in nitric oxide (NO) have been linked to vascular dysfunction during diabetic retinopathy (DR). Diabetes can reduce NO by increasing ROS and by increasing activity of arginase, which competes w...

  • Review
  • Open Access
23 Citations
8,089 Views
10 Pages

Undernutrition and Overnutrition Burden for Diseases in Developing Countries: The Role of Oxidative Stress Biomarkers to Assess Disease Risk and Interventional Strategies

  • Francesca Mastorci,
  • Cristina Vassalle,
  • Kyriazoula Chatzianagnostou,
  • Claudio Marabotti,
  • Khawer Siddiqui,
  • Ahmed Ould Eba,
  • Soueid Ahmed Sidi Mhamed,
  • Arun Bandopadhyay,
  • Marco Stefano Nazzaro and
  • Mirko Passera
  • + 1 author

The increased life expectancy, urbanization, and unhealthy lifestyle characterized by a shift towards a sedentary lifestyle and decreased energy expenditure are considered the main drivers of epidemiological transition. In particular, developing coun...

  • Review
  • Open Access
40 Citations
12,665 Views
16 Pages

The Role of NOX4 and TRX2 in Angiogenesis and Their Potential Cross-Talk

  • Chaofei Chen,
  • Li Li,
  • Huanjiao Jenny Zhou and
  • Wang Min

The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (NOX) family is the major source of reactive oxygen species (ROS) in the vascular system. In this family, NOX4, a constitutive active form of NOXs, plays an important role in angiogenesi...

  • Review
  • Open Access
36 Citations
8,908 Views
17 Pages

Angiogenesis is the formation of new blood vessels from preexisting ones and is implicated in physiologic vascular development, pathologic blood vessel growth, and vascular restoration. This is in contrast to vasculogenesis, which is de novo growth o...

  • Communication
  • Open Access
14 Citations
10,661 Views
6 Pages

Is Root Catalase a Bifunctional Catalase-Peroxidase?

  • Vasileia Chioti and
  • George Zervoudakis

Plant catalases exhibit spatial and temporal distribution of their activity. Moreover, except from the typical monofunctional catalase, a bifunctional catalase-peroxidase has been reported. The aim of this study was to investigate whether the leaf an...

  • Review
  • Open Access
90 Citations
12,516 Views
29 Pages

The Reactive Sulfur Species Concept: 15 Years On

  • Gregory I. Giles,
  • Muhammad Jawad Nasim,
  • Wesam Ali and
  • Claus Jacob

Fifteen years ago, in 2001, the concept of “Reactive Sulfur Species” or RSS was advocated as a working hypothesis. Since then various organic as well as inorganic RSS have attracted considerable interest and stimulated many new and often unexpected a...

  • Feature Paper
  • Article
  • Open Access
16 Citations
7,351 Views
14 Pages

Effects of β-Carotene and Its Cleavage Products in Primary Pneumocyte Type II Cells

  • Cornelia Haider,
  • Franziska Ferk,
  • Ekramije Bojaxhi,
  • Giuseppe Martano,
  • Hanno Stutz,
  • Nikolaus Bresgen,
  • Siegfried Knasmüller,
  • Avdulla Alija and
  • Peter M. Eckl

β-Carotene has been shown to increase the risk of developing lung cancer in smokers and asbestos workers in two large scale trails, the Beta-Carotene and Retinol Efficacy Trial (CARET) and the Alpha-Tocopherol Beta-carotene Cancer Prevention Trial (A...

  • Article
  • Open Access
11 Citations
6,175 Views
12 Pages

Hormetic Property of Ginseng Steroids on Anti-Oxidant Status against Exercise Challenge in Rat Skeletal Muscle

  • Ming-Fen Hsu,
  • Szu-Hsien Yu,
  • Mallikarjuna Korivi,
  • Wei-Horng Jean,
  • Shin-Da Lee,
  • Chih-Yang Huang,
  • Yi-Hung Liao,
  • Jessica Lu and
  • Chia-Hua Kuo

Background: Existing literature on anti-oxidant capacity of ginseng has been inconsistent due to variance in the profile of ginseng steroids (Ginsenosides) that is because of differences in seasons and species. Methods: We used various doses of ginse...

  • Article
  • Open Access
65 Citations
11,673 Views
16 Pages

Green Synthesized Zinc Oxide (ZnO) Nanoparticles Induce Oxidative Stress and DNA Damage in Lathyrus sativus L. Root Bioassay System

  • Kamal K. Panda,
  • Dambaru Golari,
  • A. Venugopal,
  • V. Mohan M. Achary,
  • Ganngam Phaomei,
  • Narasimham L. Parinandi,
  • Hrushi K. Sahu and
  • Brahma B. Panda

Zinc oxide nanoparticles (ZnONP-GS) were synthesised from the precursor zinc acetate (Zn(CH3COO)2) through the green route using the milky latex from milk weed (Calotropis gigantea L. R. Br) by alkaline precipitation. Formation of the ZnONP-GS was mo...

  • Review
  • Open Access
40 Citations
8,714 Views
21 Pages

Mitochondria are dynamic organelles that alter their organization in response to a variety of cellular cues. Mitochondria are central in many biologic processes, such as cellular bioenergetics and apoptosis, and mitochondrial network morphology can c...

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Antioxidants - ISSN 2076-3921