Special Issue "Superoxide Dismutase (SOD) Enzymes, Mimetics and Oxygen Radicals"
Deadline for manuscript submissions: closed (30 September 2017).
Interests: X-ray and Neutron Crystallography; Cancer; Biochemistry; DNA Metabolism; Modulated Crystals; Microgravity Crystal Growth; Molecular Biophysics
Interests: SOD mimetics; cell stress; cancer; epigenetics; cell cycle
Superoxide dismutases (SODs) are antioxidant enzymes that protect cells from toxic oxygen metabolites by converting superoxide into molecular oxygen and hydrogen peroxide via cyclic reduction and oxidation of an active site metal. SODs are highly conserved and ubiquitous amongst aerobic organisms and have been shown to be involved in maintaining cellular homeostasis by playing a role in cell cycle progression, maintaining normal cell metabolism and altering cell signaling. SOD activity levels are reduced in many human diseases, such as cancer, neurodegenerative disease, lung disease, and ischemia/reperfusion injury. Recently, SOD mimetics, have shown promise in enhancing the levels of SOD activity and protecting from or inhibiting the progression of these diseases.
We invite you to submit your latest research findings or a review article to this Special Issue, which will bring together current research concerning SOD and the role that SOD mimetics can play in boosting superoxide scavenging in both normal processes as well as diseased states. This research can include both in vitro and in vivo studies relating to any of the following topics: structure/function of SOD; regulation of SOD; post-translational modifications of SOD; and the role of SOD/SOD mimetics in signaling, cell metabolism, cell cycle, epigenetic regulation, cellular stress, and disease.
We look forward to your contribution.
Dr. Gloria Borgstahl
Dr. Rebecca Oberley-Deegan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Superoxide dismutase
- SOD mimetics
- Structural biology
- Cell Biology