Exercise Induced Muscle Damage and Oxidative Stress

Dear Colleagues,

Exercise-induced muscle damage (EIMD) is associated with muscle soreness or discomfort and a marked decline of muscle strength during the first 12–72 hours post-exercise. Furthermore, EIMD leads to the onset of an inflammatory response that is associated with activation of leukocytes, muscle oedema, deterioration of muscle function, delayed-onset of muscle soreness (DOMS) and several intracellular events that aim to restore the integrity and function of the affected muscle. Oxidative stress on the other hand indicates a condition where the cellular production of pro-oxidant molecules exceeds the ability of the antioxidant system to reduce reactive oxygen or nitrogen species (RONS). Research indicates that oxidative stress is evident following muscle damaging exercise. Perturbations in oxidative stress seem to have a potent role in the adaptation process following EIMD. The purpose of this Special Issue of Antioxidants is to highlight recent developments on the field of EIMD and its association with inflammation and oxidative stress. Therefore, you are invited to submit original research papers, or exceptionally, a review article that focuses upon issues that relate to causes of EIMD, like different exercise protocols, age, gender, genetics, etc., the cellular events that trigger inflammation and oxidative stress and the adaptive responses at the structural and performance level of the muscle following EIMD.

Prof. Dr. Athanasios Jamurtas
Guest Editor

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