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Brain Sciences, Volume 15, Issue 8

2025 August - 122 articles

Cover Story: This study investigated whether ischemic lesions visible in a single imaging plane correspond to smaller volumes and whether coronal DWI enhances detection compared to axial DWI alone. This retrospective single-center study examined 134 patients with brainstem ischemic strokes between December 2018 and November 2023. All patients underwent axial and coronal DWI. Clinical data, NIH Stroke Scale (NIHSS) scores, and modified Rankin Scale (mRS) scores were recorded. Diffusion-restricted lesion volumes were calculated using multiple models (planimetric, ellipsoid, and spherical), and lesion visibility per imaging plane was analyzed. View this paper
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Articles (122)

  • Review
  • Open Access
11 Citations
6,781 Views
23 Pages

Advancing Medulloblastoma Therapy in Pediatrics: Integrative Molecular Classification and Emerging Treatments

  • David T. Kim,
  • Michaela Uloho-Okundaye,
  • Stephen C. Frederico,
  • Santosh Guru and ,
  • Min J. Kim and
  • Steven D. Chang
  • + 1 author+ 0 author

21 August 2025

Medulloblastoma (MB), the most common malignant pediatric brain tumor, has undergone reclassification from a histologically defined disease to a genetically stratified spectrum of distinct subgroups: WNT, SHH, Group 3, and Group 4. Advances in molecu...

(This article belongs to the Section Neuro-oncology)
  • Article
  • Open Access
2 Citations
2,013 Views
17 Pages

21 August 2025

Background/Objectives: Developmental coordination disorder (DCD) commonly co-occurs with attention deficit hyperactivity disorder (ADHD), autism spectrum disorder (ASD), and specific learning disorder (SLD), affecting academics, mental health, and li...

(This article belongs to the Section Developmental Neuroscience)
  • Review
  • Open Access
4 Citations
14,477 Views
14 Pages

Optic Pathway Glioma: Current Treatment Approaches and Ongoing Clinical Trials

  • Osama Elzaafarany,
  • Sarah Elhomosany,
  • Alexandra Rincones,
  • Vincent Dlugi and
  • Sepideh Mokhtari

21 August 2025

Optic pathway glioma (OPG) is a rare pediatric low-grade glioma, frequently associated with neurofibromatosis type 1 (NF–1), that presents unique therapeutic challenges due to its anatomical location and its potential to impair vision, endocrin...

(This article belongs to the Section Neuroglia)
  • Review
  • Open Access
2 Citations
5,167 Views
16 Pages

21 August 2025

Recent advances in psychedelic research have renewed interest in their therapeutic potential for psychiatric disorders characterized by cognitive and behavioral rigidity. This review examines the rationale for using serotonergic psychedelics—pa...

(This article belongs to the Section Neuropsychiatry)
  • Article
  • Open Access
3 Citations
1,416 Views
18 Pages

From Scalp to Brain: Analyzing the Spatial Complexity of the Shooter’s Brain

  • Bowen Gong,
  • Xiuyan Hu,
  • Xinyu Shi,
  • Ting Shi and ,
  • Yi Qu,
  • Yunfa Fu and
  • Anmin Gong
  • + 2 authors+ 0 author

21 August 2025

Background: In recent years, complexity analysis has attracted considerable attention in the field of neural mechanism exploration due to its nonlinear characteristics, providing a new perspective for revealing the complex information processing mech...

  • Article
  • Open Access
2 Citations
1,661 Views
10 Pages

Premorbid Comorbidities as Predictors of Outcome in Ischemic Posterior Fossa Stroke: A Retrospective Evaluation Using the Age-Adjusted Charlson Comorbidity Index

  • Francesca Culaj,
  • Toska Maxhuni,
  • Stefan T. Gerner,
  • Anne Mrochen and ,
  • Tobias Braun,
  • Priyanka Boettger,
  • Maxime Viard,
  • Hagen B. Huttner,
  • Martin Jünemann and
  • Omar Alhaj Omar
  • + 5 authors+ 0 author

21 August 2025

Background: Posterior cranial fossa (PCF) infarctions are associated with elevated mortality rates; however, evidence regarding the prognostic value of comorbidity indices in this context remains scarce. This study investigates the association betwee...

(This article belongs to the Special Issue Management of Acute Stroke)
  • Review
  • Open Access
4 Citations
3,700 Views
17 Pages

21 August 2025

While technology has influenced today’s society in many aspects, how does it advance research and practice in the field of autism spectrum disorder (ASD)? In this article, we provide a narrative review of how technology enhances early detection...

(This article belongs to the Section Neuropsychology)
  • Article
  • Open Access
6 Citations
9,573 Views
19 Pages

20 August 2025

Background/Objectives: Borderline Personality Disorder (BPD) frequently overlaps with trauma-related conditions, particularly PTSD and Complex PTSD (cPTSD). Adverse Childhood Experiences (ACEs)—especially emotional and sexual abuse—are co...

(This article belongs to the Special Issue Traumatic Stress and Dissociative Disorder)
  • Article
  • Open Access
2 Citations
1,974 Views
25 Pages

20 August 2025

Background: Hearing loss is known to cause structural and functional abnormalities in the central auditory pathways. Interventions with hearing aids that amplify acoustic signals have been developed to combat hearing loss. However, little is known ab...

  • Editorial
  • Open Access
1,567 Views
4 Pages

Challenges and Perspectives of Neurological Disorders: Series II

  • Dina Nur Anggraini Ningrum and
  • Woon-Man Kung

20 August 2025

Neurological disorders (NDs) has become the foremost public health threat across the globe in recent years, resulting in upsetting and devastating outcomes [...]

(This article belongs to the Special Issue Challenges and Perspectives of Neurological Disorders: Series II)
  • Article
  • Open Access
1,459 Views
13 Pages

Dose-Dependent Dual Effect of the Endozepine ODN on Neuronal Spiking Activity

  • Mahmoud Hazime,
  • Marion Gasselin,
  • Michael Alasoadura,
  • Juliette Leclerc and ,
  • Benjamin Lefranc,
  • Magali Basille-Dugay,
  • Celine Duparc,
  • David Vaudry,
  • Jérôme Leprince and
  • Julien Chuquet
  • + 5 authors+ 0 author

20 August 2025

Background/Objectives: Endozepines known as the endogenous ligands of benzodiazepine-binding sites, include the diazepam binding inhibitor (DBI) and its processing products, the triakontatetraneuropeptide (TTN) and the octadecaneuropeptide (ODN). Des...

(This article belongs to the Section Neuroglia)
  • Article
  • Open Access
11 Citations
2,440 Views
17 Pages

20 August 2025

Background/Objectives: Electroencephalography (EEG)-based emotion recognition plays an important role in affective computing and brain–computer interface applications. However, existing methods often face the challenge of achieving high classif...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Review
  • Open Access
12 Citations
2,857 Views
26 Pages

Redox-Regulated Pathways in Glioblastoma Stem-like Cells: Mechanistic Insights and Therapeutic Implications

  • Nadia Fernanda Esteban-Román,
  • Elisa Taddei,
  • Edson Castro-Velázquez,
  • Lorna Villafuentes-Vidal and ,
  • Alejandra Velez-Herrera,
  • Moisés Rubio-Osornio and
  • Carmen Rubio
  • + 2 authors+ 0 author

19 August 2025

Glioblastoma (GBM) is the most aggressive primary brain tumor, characterized by rapid proliferation, invasiveness, therapeutic resistance, and an immunosuppressive tumor microenvironment. A subpopulation of glial stem-like cells (GSCs) within GBM tum...

(This article belongs to the Section Neuro-oncology)
  • Article
  • Open Access
8 Citations
2,955 Views
20 Pages

GAH-TNet: A Graph Attention-Based Hierarchical Temporal Network for EEG Motor Imagery Decoding

  • Qiulei Han,
  • Yan Sun,
  • Hongbiao Ye,
  • Ze Song and ,
  • Jian Zhao,
  • Lijuan Shi and
  • Zhejun Kuang
  • + 2 authors+ 0 author

19 August 2025

Background: Brain–computer interfaces (BCIs) based on motor imagery (MI) offer promising solutions for motor rehabilitation and communication. However, electroencephalography (EEG) signals are often characterized by low signal-to-noise ratios,...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
1,809 Views
15 Pages

Reproducing the Few-Shot Learning Capabilities of the Visual Ventral Pathway Using Vision Transformers and Neural Fields

  • Jiayi Su,
  • Lifeng Xing,
  • Tao Li,
  • Nan Xiang and ,
  • Jiacheng Shi and
  • Dequan Jin
  • + 1 author+ 0 author

19 August 2025

Background: Studies have shown that humans can rapidly learn the shape of new objects or adjust their behavior when encountering novel situations. Research on visual cognition in the brain further indicates that the ventral visual pathway plays a cri...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
2,072 Views
24 Pages

TARPγ2-Derived Peptide Enhances Early-Phase Long-Term Potentiation and Impairs Memory Retention in Male Rats

  • Dominik Mátyás,
  • Vanda Tukacs,
  • Vilmos Tóth,
  • Péter Baracskay and ,
  • Stefánia Krisztina Pap,
  • Pál Stráner,
  • Trần Minh Hiền,
  • Éva Hunyadi-Gulyás,
  • Zsuzsanna Darula and
  • Gábor Juhász
  • + 7 authors+ 2 authors

18 August 2025

Background/Objectives: Disruption of AMPAR trafficking at excitatory synapses contributes to impaired synaptic plasticity and memory formation in several neurological and psychiatric disorders. Arc, an immediate early gene product, has been shown to...

(This article belongs to the Section Behavioral Neuroscience)
  • Article
  • Open Access
1 Citations
3,759 Views
14 Pages

18 August 2025

Background/Objectives: Lucid dreaming (LD), during which the dreamer becomes aware of the dream state, offers a unique opportunity for a variety of applications, including motor practice, personal well-being, and nightmare therapy. However, these app...

(This article belongs to the Section Neuropsychology)
  • Article
  • Open Access
2 Citations
1,819 Views
19 Pages

Resolution of Lipopolysaccharide-Induced Inflammation Followed by DNA Hypomethylation and Increased Tetrahydrobiopterin Biosynthesis in Mouse Hippocampus

  • Jennyffer Souza,
  • Debora da Luz Scheffer,
  • Alexandre Francisco Solano,
  • Samantha Veloso and ,
  • Luisa Cruz,
  • Rodrigo Foganholi-Silva and
  • Alexandra Latini
  • + 2 authors+ 0 author

18 August 2025

Background: Robust evidence supports the role of tetrahydrobiopterin (BH4) metabolism in sustaining inflammation; however, the mechanisms underlying the persistent upregulation of the BH4 pathway remain incompletely understood. This study investigate...

(This article belongs to the Special Issue Toxic Mechanisms and Emerging Therapeutic Strategies in Brain Disorders)
  • Article
  • Open Access
2 Citations
2,363 Views
17 Pages

Spoonerism Beyond Language: A Multi-Componential Perspective on Phonological Awareness

  • Francesco Benso,
  • Noemi Mazzoni,
  • Carlo Chiorri,
  • Eleonora Ardu and ,
  • Paola Venuti and
  • Angela Pasqualotto
  • + 1 author+ 0 author

18 August 2025

Background: Reading difficulties are closely linked to phonological awareness (PA), though PA tasks vary in complexity and cognitive demands. Recent research suggests that dyslexia reflects multiple cognitive risk factors, aligned with multi-level mo...

(This article belongs to the Section Developmental Neuroscience)
  • Article
  • Open Access
4 Citations
2,384 Views
26 Pages

A Multi-Branch Network for Integrating Spatial, Spectral, and Temporal Features in Motor Imagery EEG Classification

  • Xiaoqin Lian,
  • Chunquan Liu,
  • Chao Gao,
  • Ziqian Deng and ,
  • Wenyang Guan and
  • Yonggang Gong
  • + 1 author+ 0 author

18 August 2025

Background: Efficient decoding of motor imagery (MI) electroencephalogram (EEG) signals is essential for the precise control and practical deployment of brain-computer interface (BCI) systems. Owing to the complex nonlinear characteristics of EEG sig...

(This article belongs to the Section Neurotechnology and Neuroimaging)
  • Systematic Review
  • Open Access
18 Citations
9,896 Views
18 Pages

The Relationship Between Physical Activity and Depression in College Students: A Systematic Review and Meta-Analysis

  • Xiaorui Huang,
  • Zhuying Chen,
  • Ze Xu,
  • Xiaojie Liu and ,
  • Yuanyuan Lv and
  • Laikang Yu
  • + 1 author+ 0 author

18 August 2025

Objectives: Depression is a significant and growing global concern with substantial societal impact. College students, being particularly vulnerable to depression, necessitate exploration of physical activity (PA) as a potential mitigating factor. Th...

(This article belongs to the Special Issue Unraveling the Role of Physical Activity in Brain, Cognition, and Mental Health)
  • Article
  • Open Access
3 Citations
3,221 Views
14 Pages

18 August 2025

Background: Neurodivergent students, including those with Autism Spectrum Disorder (ASD) and Attention Deficit/Hyperactivity Disorder (ADHD), frequently encounter challenges in several areas of foreign language (FL) learning, including vocabulary acq...

(This article belongs to the Special Issue Eye-Tracking Monitoring of Neurological and Psychiatric Conditions Across Life Span)
  • Article
  • Open Access
1 Citations
3,184 Views
22 Pages

Effects of Age on the Neural Tracking of Speech in Noise

  • HyunJung An,
  • JeeWon Lee,
  • Young-jin Park,
  • Myung-Whan Suh and
  • Yoonseob Lim

16 August 2025

Background: Older adults often struggle to comprehend speech in noisy environments, a challenge influenced by declines in both auditory processing and cognitive functions. This study aimed to investigate how differences in speech-in-noise perception...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
9 Citations
11,543 Views
18 Pages

The Effectiveness of an Exercise Program Based on Motor Learning Principles for the Correction of the Forward Head Posture: A Randomized Controlled Trial

  • Stephani Argyrou,
  • Pavlos Kitixis,
  • Zacharias Dimitriadis,
  • Anna Christakou and ,
  • Nikolaos Strimpakos,
  • George Paras,
  • Maria Tsioutsoumaka and
  • Eleni Kapreli
  • + 3 authors+ 0 author

15 August 2025

Background/Objectives: The aim of this study was to examine the effectiveness of an exercise program based on principles of motor learning with cognitive elements (such as attention) in the correction of Forward Head Posture (FHP). Methods: A total o...

(This article belongs to the Special Issue Neuromuscular Diseases and Musculoskeletal Disorders)
  • Article
  • Open Access
6 Citations
5,249 Views
13 Pages

B7-H3 as a Reliable Diagnostic Biomarker for the Differentiation of High-Grade Gliomas (HGGs) and Low-Grade Gliomas (LGGs)

  • Fatima Juković-Bihorac,
  • Slaviša Đuričić,
  • Emir Begagić,
  • Hakija Bečulić and ,
  • Alma Efendić,
  • Semir Vranić and
  • Mirza Pojskić
  • + 2 authors+ 0 author

15 August 2025

Background/Objectives: This study aimed to evaluate the diagnostic and prognostic utility of B7-H3 expression in differentiating low-grade gliomas (LGGs) from high-grade gliomas (HGGs) and to examine its association with clinical outcomes. Methods: T...

(This article belongs to the Special Issue Editorial Board Collection Series: Advances in Neuro-Oncology)
  • Review
  • Open Access
2 Citations
5,322 Views
25 Pages

15 August 2025

This article reviews and synthesizes highlights of the history of neural models of rate-based and spiking neural networks. It explains that theoretical and experimental results about how all rate-based neural network models, whose cells obey the memb...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
2,140 Views
13 Pages

Preliminary Results from an RCT Examining the Effects of a Health Behavior Intervention as an Adjunct to Standard Trauma Therapy Among Adults with PTSD

  • Jeffrey L. Kibler,
  • Karla Patricia Molina Valenzuela,
  • Shalynn Murphy,
  • Claudia Ocholski and ,
  • Dania Dabbagh,
  • Valeria Rangel Cunha and
  • Mindy Ma
  • + 2 authors+ 0 author

15 August 2025

Background/Objectives: Individuals with posttraumatic stress disorder (PTSD) tend to show patterns of elevated cardiovascular disease (CVD) risk earlier in life than the general population. The need for effective interventions for CVD risk-reduction...

(This article belongs to the Topic Exercise and Nutrition for Physical Performance, Mental Health and General Well-Being)
  • Article
  • Open Access
1 Citations
5,248 Views
12 Pages

15 August 2025

Background/Objectives: Tinnitus has been increasingly recognized not only as an auditory disturbance but also as a condition that is potentially linked to cognitive decline, particularly in older adults. However, the relationship between tinnitus cha...

(This article belongs to the Section Sensory and Motor Neuroscience)
  • Article
  • Open Access
3 Citations
1,976 Views
17 Pages

14 August 2025

Background/Objectives: As older adults spend increasing amounts of time indoors, concerns are rising about the neurological effects of indoor air pollution. This study examined associations between indoor air pollutants and structural brain changes i...

(This article belongs to the Section Environmental Neuroscience)
  • Review
  • Open Access
2 Citations
3,949 Views
29 Pages

14 August 2025

Huntington’s disease (HD) is an autosomal dominant neurodegenerative disorder characterized by progressive motor dysfunction, psychiatric disturbances, and cognitive decline. The pathophysiology of HD centers on a polyglutamine expansion in the...

(This article belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)
  • Article
  • Open Access
1,787 Views
19 Pages

14 August 2025

Background/Objectives: The study aimed to investigate how cognitive variables (performance IQ, verbal short-term memory, working memory, and ADHD symptomatology) impact lexical representations in children with high-functioning autism spectrum disorde...

(This article belongs to the Special Issue Recent Advances in Assessment and Rehabilitation of Communication and Language Disorders: Enhancing Innovations, Neuromodulation and AI)
  • Brief Report
  • Open Access
2 Citations
1,676 Views
10 Pages

Histopathological Changes of the Corticospinal Tract Following Hemorrhagic and Ischemic Stroke

  • Sarolta Kollai,
  • Dániel Bereczki,
  • Balázs Dobi,
  • Tibor Glasz and
  • Tibor Kovács

13 August 2025

Previous data on the time course of corticospinal tract (CST) degeneration after stroke are scarce, especially in the early phase. Using post-mortem histomorphological and immunohistochemical methods, CST degeneration (its temporal dynamics and its a...

(This article belongs to the Section Molecular and Cellular Neuroscience)
  • Article
  • Open Access
2,579 Views
30 Pages

Olfactory-Guided Behavior Uncovers Imaging and Molecular Signatures of Alzheimer’s Disease Risk

  • Hae Sol Moon,
  • Zay Yar Han,
  • Robert J. Anderson,
  • Ali Mahzarnia and ,
  • Jacques A. Stout,
  • Andrei R. Niculescu,
  • Jessica T. Tremblay and
  • Alexandra Badea
  • + 3 authors+ 0 author

13 August 2025

Background/Objectives: Olfactory impairment has been proposed as an early marker for Alzheimer’s disease (AD), yet the mechanisms linking sensory decline to genetic and environmental risk factors remain unclear. We aimed to identify early bioma...

(This article belongs to the Section Systems Neuroscience)
  • Systematic Review
  • Open Access
3 Citations
5,405 Views
19 Pages

13 August 2025

Introduction: Anxiety is a common problem during pregnancy and postpartum that can have important consequences for mothers and their babies. Having preventive psychological interventions to apply during the perinatal stage could help to reduce its ad...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
2 Citations
1,476 Views
16 Pages

Juvenile Lesions of the Cerebellar Fastigial Nucleus Cause Lasting Cognitive Deficits and Prefrontal Cortex Dysfunction in Adult Rats: Implications for the Cerebellar Cognitive Affective Syndrome

  • Franziska Maria Decker,
  • Jonas Jelinek,
  • Franck Fogaing Kamgaing,
  • Mesbah Alam and ,
  • Shadi Al-Afif,
  • Joachim K. Krauss,
  • Kerstin Schwabe and
  • Elvis J. Hermann
  • + 3 authors+ 0 author

13 August 2025

Background/Objectives: Cerebellar cognitive affective syndrome (CCAS) is a well-recognized postoperative complication in children following resection of brain tumors involving cerebellar midline structures. The fastigial nucleus is regarded as releva...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Review
  • Open Access
6 Citations
6,774 Views
22 Pages

13 August 2025

Classroom attention is a fundamental cognitive function that is crucial to effective learning and significantly influences academic performance. Recent advances in investigating neural correlates of attention in classroom environments provide insight...

(This article belongs to the Special Issue Neuroeducation: Bridging Cognitive Science and Classroom Practice)
  • Case Report
  • Open Access
3 Citations
5,772 Views
15 Pages

Downbeat Nystagmus: Case Report, Updated Review, Therapeutics, and Neurorehabilitation

  • T. Maxwell Parker,
  • Ruben Jauregui,
  • Scott N. Grossman and
  • Steven L. Galetta

13 August 2025

Introduction: Downbeat nystagmus (DBN) is an ocular motor disorder characterized by persistent to-and-fro eye movements with a slow phase directed upwards and a corrective fast phase downwards. DBN in the context of myelin oligodendrocyte glycoprotei...

(This article belongs to the Special Issue At the Frontiers of Neurorehabilitation: 3rd Edition)
  • Article
  • Open Access
2 Citations
2,800 Views
14 Pages

13 August 2025

Background/Objectives: Persons with Parkinson’s disease (PD) are at elevated risk of falling due to deficits in postural control, lower limb strength, and sensory integration. While community-based boxing programs (CBPs) have shown promise in i...

(This article belongs to the Section Neurodegenerative Diseases)
  • Review
  • Open Access
1 Citations
6,669 Views
14 Pages

12 August 2025

Dopamine has been increasingly implicated in shaping economic and financial decision-making, yet much of the evidence remains fragmented across paradigms and mechanistic levels, and heavily based on preclinical or clinical populations. This review sy...

(This article belongs to the Special Issue Advances in Dopamine and Cognition)
  • Article
  • Open Access
4 Citations
3,017 Views
16 Pages

Predicting State Anxiety Level Change Using EEG Parameters: A Pilot Study in Two Museum Settings

  • Maria Elide Vanutelli,
  • Annalisa Banzi,
  • Maria Cicirello,
  • Raffaella Folgieri and
  • Claudio Lucchiari

11 August 2025

Background: Museums are increasingly being recognized not only as cultural institutions but also as potential resources for enhancing psychological well-being. Prior research has shown that museum visits can reduce stress and anxiety, yet there is a...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Article
  • Open Access
4 Citations
2,996 Views
29 Pages

Automated Sleep Stage Classification Using PSO-Optimized LSTM on CAP EEG Sequences

  • Manjur Kolhar,
  • Manahil Mohammed Alfuraydan,
  • Abdulaziz Alshammary,
  • Khalid Alharoon and ,
  • Abdullah Alghamdi,
  • Ali Albader,
  • Abdulmalik Alnawah and
  • Aryam Alanazi
  • + 3 authors+ 0 author

11 August 2025

The automatic classification of sleep stages and Cyclic Alternating Pattern (CAP) subtypes from electroencephalogram (EEG) recordings remains a significant challenge in computational sleep research because of the short duration of CAP events and the...

  • Review
  • Open Access
21 Citations
9,101 Views
22 Pages

11 August 2025

Autism spectrum disorder (ASD) deals with several symptoms, including language and speech impairment and developmental delays. The main brain regions affected could be the prefrontal cortex (PFC) or the temporal lobe. The detrimental features could i...

(This article belongs to the Special Issue Role of Inflammation, Oxidative Stress, and Metabolic Dysfunction in Neurodevelopmental and Neurodegenerative Diseases: Pharmacological Targets and Therapeutic Interventions)
  • Article
  • Open Access
10 Citations
3,969 Views
16 Pages

Comparing Immersive and Non-Immersive VR: Effects on Spatial Learning and Aesthetic Experience in Museum Settings

  • Laura Piccardi,
  • Marcello Massidda,
  • Laura Travaglini,
  • Sofia Pescarin and ,
  • Marco Giancola,
  • Massimiliano Palmiero,
  • Matteo Deflorian,
  • Sabrina Apollaro,
  • Roberta Lista and
  • Raffaella Nori
  • + 5 authors+ 0 author

11 August 2025

Background/Objectives: The use of virtual reality (VR) solutions in design has rapidly increased globally. However, it remains unclear to what extent these technologies enhance people’s cognitive abilities. Understanding the impact of such tech...

(This article belongs to the Section Behavioral Neuroscience)
  • Brief Report
  • Open Access
1 Citations
1,359 Views
8 Pages

Cerebral Microbleeds with a Venous Connection on 3 Tesla Susceptibility-Weighted Imaging in Persons with Alzheimer’s Disease and Healthy Aging Controls

  • Ulf Jensen-Kondering,
  • Veronique Kuhn,
  • Hannes Schacht,
  • Alexander Neumann and ,
  • Georg Royl and
  • Peter Schramm
  • + 1 author+ 0 author

10 August 2025

Introduction: It has been recently demonstrated that some cerebral microbleeds (CMBs) are connected to cerebral veins in patients with cerebral small vessel disease (CSVD) including cerebral amyloid angiopathy (CAA). We sought to demonstrate the pres...

(This article belongs to the Section Neurosurgery and Neuroanatomy)
  • Review
  • Open Access
2 Citations
5,738 Views
15 Pages

Background and aim of this review: The ongoing opioid epidemic underscores the urgent need for innovative pharmacological and behavioral interventions to mitigate the impact of opioid use disorder (OUD). This review aims to explore theoretical overla...

(This article belongs to the Topic New Advances in Addiction Behavior)
  • Systematic Review
  • Open Access
12 Citations
5,842 Views
44 Pages

Background: Aluminum accumulation in the brain causes cognitive deficits. No comprehensive synthesis of pharmacological treatments against aluminum neurotoxicity has been conducted, which led us to systematically review the effects of various pharmac...

(This article belongs to the Section Cognitive, Social and Affective Neuroscience)
  • Review
  • Open Access
2,731 Views
16 Pages

Background: The COVID-19 pandemic exposed the fragility of educational systems in ensuring inclusive schooling, especially for students with Autism Spectrum Disorder (ASD). Disruptions to daily routines, the shift to remote learning, and the suspensi...

(This article belongs to the Special Issue Advances in Educational Neuroscience: Current Status and Future Directions)
  • Communication
  • Open Access
7 Citations
1,887 Views
9 Pages

Differential Neuroendocrine Responses and Dysregulation of the Hypothalamic–Pituitary–Adrenal Axis Following Repeated Mild Concussive Impacts and Blast Exposures in a Rat Model

  • Rex Jeya Rajkumar Samdavid Thanapaul,
  • Jishnu K. S. Krishnan,
  • Manoj Y. Govindarajulu,
  • Chetan Y. Pundkar and ,
  • Gaurav Phuyal,
  • Joseph B. Long and
  • Peethambaran Arun
  • + 2 authors+ 0 author

Traumatic brain injury (TBI) remains a significant public health concern, particularly among military personnel and contact sport athletes who are frequently exposed to repeated blast overpressure waves and mild concussive impacts, respectively. Whil...

(This article belongs to the Special Issue Editorial Board Collection Series: Innovative Research in Molecular and Cellular Neuroscience for Regulation of Cell Death Mechanisms for Functional Neuroprotection)

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Brain Sci. - ISSN 2076-3425