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Brain Sciences, Volume 15, Issue 9

2025 September - 128 articles

Cover Story: In this study, participants carried out experimental tasks able to replicate the Skill (tracking task), Rule (rule-based navigation) and Knowledge conditions (unfamiliar situations). Results: Participants’ Electroencephalogram (EEG) was recorded during task execution, and then Global Field Power (GFP) was estimated in the different EEG frequency bands. Brodmann areas (BAs) and EEG features were then used to characterize the S-R-K pattern over the cerebral cortex and as inputs to develop the machine learning-based model to estimate participants’ cognitive control behaviours while dealing with tasks. The results demonstrate the possibility of objectively measuring the different S, R and K levels in terms of brain activations. Furthermore, such evidence is consistent with the scientific literature in terms of cognitive functions corresponding to the different levels of cognitive control. View this paper
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Articles (128)

  • Article
  • Open Access
1,002 Views
24 Pages

22 September 2025

Background/Objectives: Glutamatergic neurotransmission is essential for the normal functioning of the retina. Photoreceptor to bipolar and bipolar to ganglion cell signaling is mediated by L-glutamate, which is stored in and released from vesicular g...

  • Article
  • Open Access
784 Views
16 Pages

22 September 2025

Introduction: Leukoaraiosis (LA) or white matter disease is a significant component of vascular dementia. There is a large overlap noted between normal-pressure hydrocephalus (NPH) and LA. A previously reported lumped parameter modelling study of NPH...

  • Review
  • Open Access
1,529 Views
33 Pages

22 September 2025

Language, a uniquely human cognitive faculty, is fundamentally characterized by its capacity for complex thoughts and structured expressions. This review examines two critical measures of linguistic performance: idea density (ID) and grammatical comp...

  • Study Protocol
  • Open Access
1,603 Views
14 Pages

Accelerated Optimized Protocol of Intermittent Theta-Burst Stimulation for Negative Symptoms in Schizophrenia (ACTh-NS): A Randomized, Double-Blind, Sham-Controlled Study Design

  • Ivan Taiar,
  • July Silveira Gomes,
  • Lucas Jorge,
  • Carolina Ziebold,
  • André Fernandes,
  • Renan Biokino,
  • Pedro Lorencetti,
  • André Brunoni and
  • Ary Gadelha

22 September 2025

Introduction: Intermittent theta burst stimulation (iTBS) has been associated with improvements in the negative symptoms (NSs) of schizophrenia. However, optimizing by shorter protocols remains necessary. Furthermore, understanding their impact on ot...

  • Case Report
  • Open Access
847 Views
18 Pages

20 September 2025

Background: Vitamin A deficiency (VAD) can occur due to malnutrition or reduced intestinal absorption, such as in short bowel syndrome (SBS). The main causes of SBS in adults include post-radiotherapy and surgery (e.g., repeated bowel resections). VA...

  • Article
  • Open Access
1 Citations
778 Views
12 Pages

CT-Based Quantitative Analysis of Ossification Centres in the C7 Vertebra of Human Fetuses

  • Magdalena Grzonkowska,
  • Michał Kułakowski,
  • Karol Elster,
  • Bartłomiej Hankiewicz,
  • Michał Janiak,
  • Agnieszka Rogalska,
  • Milena Świtońska,
  • Andrzej Żytkowski and
  • Mariusz Baumgart

20 September 2025

Objectives: The present study aimed to analyze the growth dynamics of the ossification centers of the seventh cervical (C7) vertebra in the human fetus, focusing on linear, planar, and volumetric parameters of both the vertebral body and neural proce...

  • Review
  • Open Access
803 Views
16 Pages

Navigating a Misty Road: Novel Ways to Study the Impact of Cognition on Driving Performance in Multiple Sclerosis

  • Ioannis Nikolakakis,
  • Panagiotis Grigoriadis,
  • Nefeli Dimitriou,
  • Dimitrios Parisis,
  • Grigorios Nasios,
  • Lambros Messinis and
  • Christos Bakirtzis

20 September 2025

Background/Objectives: The ability to drive is closely linked to participation in daily activities and quality of life in people living with neurological disorders. Cognitive deficits in people with multiple sclerosis (pwMS) are known to hinder this...

  • Article
  • Open Access
1,027 Views
13 Pages

Long-Term Preservation of Human Head and Neck Specimens for Neurosurgical Training: A Technical Note

  • Francesco Signorelli,
  • Valid Rastegar,
  • Matteo Palermo,
  • Domenico Laino,
  • Fabio Zeoli and
  • Massimiliano Visocchi

20 September 2025

Purpose: Cadaveric dissection is a cornerstone of neurosurgical education, providing trainees with a realistic 3D understanding of anatomy and a safe environment to practice surgical approaches. A preservation technique was developed that merges the...

  • Article
  • Open Access
1,738 Views
15 Pages

A BIO-EEG Hyperscanning Study of Moral Dyadic Negotiation

  • Angelica Daffinà,
  • Laura Angioletti and
  • Michela Balconi

19 September 2025

Background/Objectives: Recent social neuroscience research has increasingly shifted from individual moral decision-making to the study of how people negotiate moral dilemmas in interpersonal contexts. This multimethod hyperscanning study investigated...

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Brain Sci. - ISSN 2076-3425