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Brain Sciences, Volume 13, Issue 12

December 2023 - 121 articles

Cover Story: Diagnostic criteria for vestibular migraine (VM) describe this as an episodic disorder. However, some patients report prolonged (>72 h duration) or even persistent VM symptoms, prompting whether a chronic VM variant should be introduced. But is this different from other chronic vestibular syndromes such as persistent postural-perceptual dizziness (PPPD)? PPPD may arise from recurrent VM episodes, but also independently of VM. Whilst there may be subtle clinical differences between these groups, we argue that the underlying mechanisms of persistent dizziness overlap regardless of the trigger. This has implications for the treatment of persistent dizziness in the context of VM, moving away from pharmacotherapy and towards combined physical and cognitive behavioural therapies. View this paper
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Articles (121)

  • Systematic Review
  • Open Access
10 Citations
7,400 Views
9 Pages

Emotional Dysregulation and Post-Traumatic Stress Symptoms: Which Interaction in Adolescents and Young Adults? A Systematic Review

  • Lorenzo Conti,
  • Sara Fantasia,
  • Miriam Violi,
  • Valerio Dell’Oste,
  • Virginia Pedrinelli and
  • Claudia Carmassi

18 December 2023

Emotional dysregulation (ED) has recently been conceptualized as a transnosographic entity in major mental disorders, and increasing evidence has suggested association between ED and post-traumatic stress symptoms (PTSS), though the nature of this as...

  • Systematic Review
  • Open Access
2 Citations
3,564 Views
23 Pages

Challenge Level Contributes to the Efficacy of Treadmill Interventions after Stroke: A Systematic Review and Meta-Analysis

  • Sharon Olsen,
  • Gemma Alder,
  • Usman Rashid,
  • Emeline Gomes,
  • Madeleine Aislabie,
  • Fran Chee,
  • Caitlin Smith,
  • Brody Kean,
  • Nicola Towersey and
  • Nada Signal

18 December 2023

Intervention parameters such as the challenge, amount, and dosage (challenge × amount) have the potential to alter the efficacy of rehabilitation interventions after stroke. This systematic review investigated the effect of intervention paramet...

  • Article
  • Open Access
7 Citations
6,324 Views
15 Pages

18 December 2023

Objective: This was an open-label pilot study to test the feasibility and preliminary efficacy of a wearable digital intervention developed to improve on-task behavior. This was an exploratory study to test for specificity of response on parent- and...

  • Systematic Review
  • Open Access
14 Citations
5,193 Views
17 Pages

A Systematic Review of Nanomedicine in Glioblastoma Treatment: Clinical Efficacy, Safety, and Future Directions

  • Minaam Farooq,
  • Gianluca Scalia,
  • Giuseppe E. Umana,
  • Urja A. Parekh,
  • Faiza Naeem,
  • Sayeda Fatima Abid,
  • Muhammad Hammad Khan,
  • Shah Gul Zahra,
  • Hrishikesh P. Sarkar and
  • Bipin Chaurasia

18 December 2023

Background: Glioblastoma (GBM) is categorized as a grade IV astrocytoma by the World Health Organization (WHO), representing the most aggressive and prevalent form of glioma. It presents a significant clinical challenge, with limited treatment option...

  • Article
  • Open Access
5 Citations
2,689 Views
13 Pages

Treadmill Exercise Reverses the Adverse Effects of Intermittent Fasting on Behavior and Cortical Spreading Depression in Young Rats

  • Amanda Ferraz Braz,
  • Maria Luísa Figueira de Oliveira,
  • Dominique Hellen Silva da Costa,
  • Francisco Leonardo Torres-Leal and
  • Rubem Carlos Araújo Guedes

17 December 2023

Intermittent fasting (IF) and physical exercise (PE) have beneficial psychological and physiological effects, improving memory and anxiety-like behavior. However, the impact of this combination on brain electrophysiological patterns is unknown. We ai...

  • Review
  • Open Access
3 Citations
2,882 Views
17 Pages

Outcome Measures Utilized to Assess the Efficacy of Telerehabilitation for Post-Stroke Rehabilitation: A Scoping Review

  • Ardalan Shariat,
  • Mahboubeh Ghayour Najafabadi,
  • Noureddin Nakhostin Ansari,
  • Albert T. Anastasio,
  • Kian Bagheri,
  • Gholamreza Hassanzadeh and
  • Mahsa Farghadan

17 December 2023

Introduction: Outcome measures using telerehabilitation (TR) in the context of post-stroke rehabilitation are an area of emerging research. The current review assesses the literature related to TR for patients requiring post-stroke rehabilitation. Th...

  • Article
  • Open Access
2 Citations
2,357 Views
16 Pages

17 December 2023

Counterfactual conditionals posit hypothetical scenarios in which antecedent events contradict reality. This study examined whether and how the processing difficulty of Chinese counterfactual conditionals (yaobushi, equivalent to if it had not been f...

  • Systematic Review
  • Open Access
21 Citations
4,221 Views
26 Pages

Limitations in Evaluating Machine Learning Models for Imbalanced Binary Outcome Classification in Spine Surgery: A Systematic Review

  • Marc Ghanem,
  • Abdul Karim Ghaith,
  • Victor Gabriel El-Hajj,
  • Archis Bhandarkar,
  • Andrea de Giorgio,
  • Adrian Elmi-Terander and
  • Mohamad Bydon

16 December 2023

Clinical prediction models for spine surgery applications are on the rise, with an increasing reliance on machine learning (ML) and deep learning (DL). Many of the predicted outcomes are uncommon; therefore, to ensure the models’ effectiveness...

  • Review
  • Open Access
9 Citations
3,090 Views
14 Pages

Auditory Steady-State Responses in Schizophrenia: An Updated Meta-Analysis

  • Inès Zouaoui,
  • Alexandre Dumais,
  • Marc E. Lavoie and
  • Stéphane Potvin

16 December 2023

This meta-analysis investigates auditory steady-state responses (ASSRs) as potential biomarkers of schizophrenia, focusing on previously unexplored clinical populations, frequencies, and variables. We examined 37 studies, encompassing a diverse cohor...

  • Article
  • Open Access
5 Citations
2,151 Views
12 Pages

16 December 2023

Previous research has documented brain plasticity after an anterior cruciate ligament (ACL) tear and suggests that these neural adaptations contribute to poorer motor control. Since both brain hemispheres show adaptations, we hypothesized that reduce...

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Brain Sci. - ISSN 2076-3425Creative Common CC BY license