You are currently viewing a new version of our website. To view the old version click .

Brain Sciences, Volume 10, Issue 1

January 2020 - 57 articles

Cover Story: Glioblastoma (GB) are a grade IV aggressive brain tumor with limited treatment options available (chemo- and radiation therapy). The usual lifespan of patients is about 18 months following treatment. To extend the quality of life beyond this boundary, better approaches are necessary, such as targeted gene and drug therapy, use of oncolytic virus, and nutraceuticals. Some of these treatments can reach the GB brain, crossing the blood–brain barrier following systemic injections; however, most of them are failing. To overcome this issue, we and others have used nanoparticles as a vehicle to deliver therapeutics to the brain following systemic injections. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (57)

  • Article
  • Open Access
23 Citations
9,244 Views
8 Pages

Morning Headache as an Obstructive Sleep Apnea-Related Symptom among Sleep Clinic Patients—A Cross-Section Analysis

  • Jakub Spałka,
  • Konrad Kędzia,
  • Wojciech Kuczyński,
  • Aleksandra Kudrycka,
  • Aleksandra Małolepsza,
  • Piotr Białasiewicz and
  • Łukasz Mokros

19 January 2020

Morning headache is considered to be a symptom of obstructive sleep apnea syndrome (OSAS). Despite not being as common as excessive daytime sleepiness or unrefreshing sleep, it can similarly impair everyday activities. The aim of the present study wa...

  • Article
  • Open Access
7 Citations
5,313 Views
21 Pages

Motor Program Transformation of Throwing Dart from the Third-Person Perspective

  • Alexey Tumialis,
  • Alexey Smirnov,
  • Kirill Fadeev,
  • Tatiana Alikovskaia,
  • Pavel Khoroshikh,
  • Alexander Sergievich and
  • Kirill Golokhvast

18 January 2020

The perspective of perceiving one’s action affects its speed and accuracy. In the present study, we investigated the change in accuracy and kinematics when subjects throw darts from the first-person perspective and the third-person perspective...

  • Review
  • Open Access
58 Citations
8,696 Views
29 Pages

Neurofilaments: The C-Reactive Protein of Neurology

  • Kate L. Lambertsen,
  • Catarina B. Soares,
  • David Gaist and
  • Helle H. Nielsen

18 January 2020

Neurofilaments (NFs) are quickly becoming the biomarkers of choice in the field of neurology, suggesting their use as an unspecific screening marker, much like the use of elevated plasma C-reactive protein (CRP) in other fields. With sensitive techni...

  • Perspective
  • Open Access
11 Citations
5,024 Views
8 Pages

A New Treatment Opportunity for DIPG and Diffuse Midline Gliomas: 5-ALA Augmented Irradiation, the 5aai Regimen

  • Richard E. Kast,
  • Alex P. Michael,
  • Iacopo Sardi,
  • Terry C. Burns,
  • Tim Heiland,
  • Georg Karpel-Massler,
  • Francois G. Kamar and
  • Marc-Eric Halatsch

17 January 2020

Prognosis for diffuse intrinsic pontine glioma (DIPG) and generally for diffuse midline gliomas (DMG) has only marginally improved over the last ~40 years despite dozens of chemotherapy and other therapeutic trials. The prognosis remains invariably f...

  • Article
  • Open Access
17 Citations
4,772 Views
13 Pages

Impaired Expression of Tetraspanin 32 (TSPAN32) in Memory T Cells of Patients with Multiple Sclerosis

  • Maria Sofia Basile,
  • Emanuela Mazzon,
  • Katia Mangano,
  • Manuela Pennisi,
  • Maria Cristina Petralia,
  • Salvo Danilo Lombardo,
  • Ferdinando Nicoletti,
  • Paolo Fagone and
  • Eugenio Cavalli

17 January 2020

Tetraspanins are a conserved family of proteins involved in a number of biological processes. We have previously shown that Tetraspanin-32 (TSPAN32) is significantly downregulated upon activation of T helper cells via anti-CD3/CD28 stimulation. On th...

  • Article
  • Open Access
13 Citations
4,630 Views
10 Pages

Caucasian Infants’ Attentional Orienting to Own- and Other-Race Faces

  • Jonathan E. Prunty,
  • Kelsey C. Jackson,
  • Jolie. R. Keemink and
  • David J. Kelly

17 January 2020

Infants show preferential attention toward faces and detect faces embedded within complex naturalistic scenes. Newborn infants are insensitive to race, but rapidly develop differential processing of own- and other-race faces. In the present study, we...

  • Reply
  • Open Access
3 Citations
3,511 Views
17 Pages

17 January 2020

In this work, we discussed and counter-commented van der Helm’s comments on our previous paper (Pinna and Conti, Brain Sci., 2019, 9, 149), where we demonstrated unique and relevant visual properties imparted by contrast polarity in eliciting a...

  • Article
  • Open Access
14 Citations
5,196 Views
12 Pages

Polypharmacy Is Associated with Lower Memory Function in African American Older Adults

  • Shervin Assari,
  • Cheryl Wisseh,
  • Mohammed Saqib and
  • Mohsen Bazargan

16 January 2020

Although previous research has linked polypharmacy to lower cognitive function in the general population, we know little about this association among economically challenged African American (AA) older adults. This study explored the link between pol...

  • Comment
  • Open Access
4 Citations
4,747 Views
11 Pages

16 January 2020

Pinna and Conti (Brain Sci., 2019, 9, 149, doi:10.3390/brainsci9060149) presented phenomena concerning the salience and role of contrast polarity in human visual perception, particularly in amodal completion. These phenomena are indeed illustrative t...

  • Article
  • Open Access
9 Citations
4,371 Views
20 Pages

15 January 2020

Automobiles for our roadways are increasingly using advanced driver assistance systems. The adoption of such new technologies requires us to develop novel perception systems not only for accurately understanding the situational context of these vehic...

of 6

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Brain Sci. - ISSN 2076-3425