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Open AccessArticle

Morning Headache as an Obstructive Sleep Apnea-Related Symptom among Sleep Clinic Patients—A Cross-Section Analysis

Department of Sleep Medicine and Metabolic Disorders, Medical University of Lodz, 90-001 Lodz, Poland
Clinic of Thoracic Surgery, General and Oncological Surgery, USK im. WAM CSW, 90-549 Lodz, Poland
Department of Clinical Pharmacology, Medical University of Lodz, 90-153 Lodz, Poland
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Brain Sci. 2020, 10(1), 57;
Received: 8 December 2019 / Revised: 11 January 2020 / Accepted: 13 January 2020 / Published: 19 January 2020
(This article belongs to the Special Issue Disturbances of Sleep Among Older People)
Morning headache is considered to be a symptom of obstructive sleep apnea syndrome (OSAS). Despite not being as common as excessive daytime sleepiness or unrefreshing sleep, it can similarly impair everyday activities. The aim of the present study was to evaluate the prevalence of and factors associated with morning headaches (MH) among patients referred for polysomnography due to suspected OSAS. This is a retrospective study on 1131 patients who underwent polysomnography between 2013 and 2015. Morning headaches (MH) were reported in 29% of them. In a logistic regression model, a rise in the n probability of MH was associated with female sex (odds ratio, OR, 1.38, 95% confidence interval, CI, 1.08–1.75), history of hypertension (OR 1.25, 95% CI 1.06–1.46), complaint on unrefreshing sleep (OR 1.42, 95% CI 1.19–1.70), choking at night (OR 1.25, 95% CI 1.05–1.49), and fall in total sleep time (OR 0.872 per each hour, 95% CI 0.76–0.99). The risk between MH and apnea–hypopnea index, blood oxygen saturation parameters or arousal index was found to be statistically insignificant. There is a lack of evidence that MH is associated with the severity of OSAS or nocturnal hypoxemia. View Full-Text
Keywords: OSAS; risk factors of OSAS; morning headaches; BMI OSAS; risk factors of OSAS; morning headaches; BMI
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Spałka, J.; Kędzia, K.; Kuczyński, W.; Kudrycka, A.; Małolepsza, A.; Białasiewicz, P.; Mokros, Ł. Morning Headache as an Obstructive Sleep Apnea-Related Symptom among Sleep Clinic Patients—A Cross-Section Analysis. Brain Sci. 2020, 10, 57.

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