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Microorganisms, Volume 7, Issue 3

March 2019 - 31 articles

Cover Story: Mycobacterial membrane protein large (MmpL) proteins are integral membrane transporters that export large, complex substrates across the plasma membrane of Mycobacterium tuberculosis (Mtb). These substrates play an essential role in Mtb’s physiology and enable its specialized lifestyle as a human pathogen. This review summarizes recent advancements in our understanding of the basis of MmpL-mediated transport and the contribution of MmpL-exported substrates to the virulence and pathogenicity of Mtb in a human host. View this paper.
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Articles (31)

  • Article
  • Open Access
17 Citations
6,201 Views
22 Pages

Supercoil Levels in E. coli and Salmonella Chromosomes Are Regulated by the C-Terminal 35–38 Amino Acids of GyrA

  • Nikolay S. Rovinskiy,
  • Andrews A. Agbleke,
  • Olga N. Chesnokova and
  • N. Patrick Higgins

Prokaryotes have an essential gene—gyrase—that catalyzes negative supercoiling of plasmid and chromosomal DNA. Negative supercoils influence DNA replication, transcription, homologous recombination, site-specific recombination, genetic tr...

  • Article
  • Open Access
16 Citations
6,216 Views
15 Pages

Variovorax sp. Has an Optimum Cell Density to Fully Function as a Plant Growth Promoter

  • Oyungerel Natsagdorj,
  • Hisayo Sakamoto,
  • Dennis Marvin O. Santiago,
  • Christine D. Santiago,
  • Yoshitake Orikasa,
  • Kazuyuki Okazaki,
  • Seishi Ikeda and
  • Takuji Ohwada

Utilization of plant growth-promoting bacteria colonizing roots is environmentally friendly technology instead of using chemicals in agriculture, and understanding of the effects of their colonization modes in promoting plant growth is important for...

  • Article
  • Open Access
13 Citations
4,910 Views
17 Pages

Vaccination is an effective prevention of influenza infection. However, certain individuals develop a lower antibody response after vaccination, which may lead to susceptibility to subsequent infection. An important challenge in human health is to fi...

  • Article
  • Open Access
83 Citations
6,964 Views
11 Pages

Two bacteria capable of efficiently degrading atrazine were isolated from soil, and named ATLJ-5 and ATLJ-11. ATLJ-5 and ATLJ-11 were identified as Bacillus licheniformis and Bacillus megaterium, respectively. The degradation efficiency of atrazine (...

  • Article
  • Open Access
97 Citations
10,038 Views
10 Pages

Characterization a Novel Butyric Acid-Producing Bacterium Collinsella aerofaciens Subsp. Shenzhenensis Subsp. Nov.

  • Panpan Qin,
  • Yuanqiang Zou,
  • Ying Dai,
  • Guangwen Luo,
  • Xiaowei Zhang and
  • Liang Xiao

Butyrate-producing bacteria can biosynthesize butyrate and alleviate inflammatory diseases. However, few studies have reported that the genus Collinsella has the ability to produce butyric acid. Here, our study depicts a Collinsella strain, which is...

  • Review
  • Open Access
123 Citations
12,350 Views
22 Pages

Previously known as Enterobacter sakazakii from 1980 to 2007, Cronobacter sakazakii is an opportunistic bacterium that survives and persists in dry and low-moisture environments, such as powdered infant formula. Although C. sakazakii causes disease i...

  • Article
  • Open Access
16 Citations
5,273 Views
12 Pages

The consumption of various meats prevalent throughout the world affects host health probably by associating with compositional shifts of gut microbiota. However, the responses of gut microbiota to different types of meat are not well understood. In t...

  • Review
  • Open Access
42 Citations
5,690 Views
10 Pages

Establishment of Listeria monocytogenes in the Gastrointestinal Tract

  • Morgan L. Davis,
  • Steven C. Ricke and
  • Janet R. Donaldson

Listeria monocytogenes is a Gram positive foodborne pathogen that can colonize the gastrointestinal tract of a number of hosts, including humans. These environments contain numerous stressors such as bile, low oxygen and acidic pH, which may impact t...

  • Article
  • Open Access
49 Citations
6,045 Views
18 Pages

Response Surface Methodology Optimization of an Acidic Protease Produced by Penicillium bilaiae Isolate TDPEF30, a Newly Recovered Endophytic Fungus from Healthy Roots of Date Palm Trees (Phoenix dactylifera L.)

  • Fedia Ben Mefteh,
  • Fakher Frikha,
  • Amal Daoud,
  • Ali Chenari Bouket,
  • Lenka Luptakova,
  • Faizah N. Alenezi,
  • Bader S. Al-Anzi,
  • Tomasz Oszako,
  • Neji Gharsallah and
  • Lassaad Belbahri

To explore proteolytic activity of endophytic fungi inhabiting date palm roots, a Penicillium bilaiae isolate, displaying the highest level of protease production, has been recovered. Response surface methodology (RSM) was applied to optimize culture...

  • Article
  • Open Access
56 Citations
8,615 Views
14 Pages

Biofilm Specific Activity: A Measure to Quantify Microbial Biofilm

  • Laura Corte,
  • Debora Casagrande Pierantoni,
  • Carlo Tascini,
  • Luca Roscini and
  • Gianluigi Cardinali

Microbes growing onto solid surfaces form complex 3-D biofilm structures characterized by the production of extracellular polymeric compounds and an increased resistance to drugs. The quantification of biofilm relays currently on a number of differen...

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Microorganisms - ISSN 2076-2607Creative Common CC BY license