You are currently viewing a new version of our website. To view the old version click .

Pathogens, Volume 11, Issue 1

January 2022 - 109 articles

Cover Story: Helicobacter pylori is a gastric pathogen that exploits multiple host signaling pathways, leading to the disruption of key cell functions. Two bacterial virulence factors play important roles in this scenario, the vacuolating cytotoxin VacA and the translocated effector protein CagA of the cag type IV secretion system (T4SS). Specifically, by overruling the phosphorylation status of cortactin, H. pylori alternates the activity of molecular interaction partners of this important protein, thereby manipulating the performance of cytoskeletal rearrangements, endosomal trafficking, and cell movement. Here, we found that cortactin is necessary for the effective induction of T4SS- and CagA-dependent AGS cell movement and elongation but is dispensable for VacA uptake and formation of VacA-dependent vacuole formation and cell apoptosis. View this paper.
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (109)

  • Article
  • Open Access
7 Citations
5,155 Views
11 Pages

Prevalence of Toxoplasma gondii Measured by Western Blot, ELISA and DNA Analysis, by PCR, in Cats of Western Mexico

  • María de la Luz Galván-Ramírez,
  • Claudia Charles-Niño,
  • César Pedroza-Roldán,
  • Carolina Salazar-Reveles,
  • Karen Lissete Ocampo-Figueroa,
  • Laura Roció Rodríguez-Pérez and
  • Varinia Margarita Paez-Magallán

17 January 2022

Toxoplasma gondii is the causative agent of toxoplasmosis in humans and animals. The sexual reproductive cycle of Toxoplasma takes place in the small intestine of felines, the definitive hosts. In the final part of the sexual cycle, T. gondii forms o...

  • Article
  • Open Access
1 Citations
2,254 Views
7 Pages

An Artefactual Cluster of Mycobacterium abscessus Pneumonia among Cancer Patients Arising from Contamination

  • Giusy Diella,
  • Giuseppina Caggiano,
  • Francesco Triggiano,
  • Marco Lopuzzo,
  • Francesca Apollonio,
  • Michele Mastria,
  • Luigi Ronga,
  • Lucia Bonadonna,
  • Luca Lucentini and
  • Antonia Pece
  • + 2 authors

17 January 2022

The Mycobacteriumabscessus complex (MABC) is a group of rapidly growing, nontuberculous mycobacteria that are ubiquitous in soil, urban water pipes, swimming pools, and drinking water. Members of the MABC are considered opportunistic pathogens. The a...

  • Article
  • Open Access
3 Citations
2,792 Views
8 Pages

West Nile Virus in Common Wild Avian Species in Israel

  • Gili Schvartz,
  • Sharon Tirosh-Levy,
  • Shahar Bider,
  • Avishai Lublin,
  • Yigal Farnoushi,
  • Oran Erster and
  • Amir Steinman

17 January 2022

In order to evaluate the contribution of different wild bird species to West Nile virus (WNV) circulation in Israel, during the months preceding the 2018 outbreak that occurred in Israel, we randomly sampled 136 frozen carcasses of a variety of avian...

  • Article
  • Open Access
14 Citations
4,078 Views
17 Pages

Molecular Detection of Tick-Borne Agents in Cats from Southeastern and Northern Brazil

  • Marcos Rogério André,
  • Ana Cláudia Calchi,
  • Maria Eduarda Chiaradia Furquim,
  • Isabela de Andrade,
  • Paulo Vitor Cadina Arantes,
  • Lara Cristina de Melo Lopes,
  • Iuri Kauan Lins do Nascimento Demarchi,
  • Mayra Araguaia Pereira Figueiredo,
  • Cirilo Antonio de Paula Lima and
  • Rosangela Zacarias Machado

16 January 2022

Even though the epidemiology of tick-borne agents (TBA) in dogs has been extensively investigated around the world, the occurrence, vectors involved, and molecular identity of these agents in cats remains elusive in many regions. Among TBA, Ehrlichia...

  • Article
  • Open Access
15 Citations
3,557 Views
14 Pages

Giardia duodenalis in Wildlife: Exploring Genotype Diversity in Italy and across Europe

  • Isabel Guadano Procesi,
  • Margherita Montalbano Di Filippo,
  • Claudio De Liberato,
  • Andrea Lombardo,
  • Giuseppina Brocherel,
  • Stefania Perrucci,
  • David Di Cave and
  • Federica Berrilli

16 January 2022

Fragmented data are so far available on genotype diversity of G. duodenalis in wildlife in different countries in Europe, in particular, in Italy. In the present study, G. duodenalis sequences obtained from different Italian wild animals [12 porcupin...

  • Article
  • Open Access
7 Citations
4,631 Views
14 Pages

Phenotypic Selection of Dairy Cattle Infected with Bovine Leukemia Virus Demonstrates Immunogenetic Resilience through NGS-Based Genotyping of BoLA MHC Class II Genes

  • Chaelynne E. Lohr,
  • Kelly R. B. Sporer,
  • Kelsey A. Brigham,
  • Laura A. Pavliscak,
  • Matelyn M. Mason,
  • Andrew Borgman,
  • Vickie J. Ruggiero,
  • Tasia M. Taxis,
  • Paul C. Bartlett and
  • Casey J. Droscha

15 January 2022

Characterization of the bovine leukocyte antigen (BoLA) DRB3 gene has shown that specific alleles associate with susceptibility or resilience to the progression of bovine leukemia virus (BLV), measured by proviral load (PVL). Through surveillance of...

  • Review
  • Open Access
21 Citations
7,185 Views
23 Pages

15 January 2022

The protozoan Cryptosporidium parvum is one of the major causative pathogens of diarrhoea in young ruminants; therefore, it causes economic losses and impairs animal welfare. Besides C. parvum, there are many other non-infectious and infectious facto...

  • Communication
  • Open Access
10 Citations
2,777 Views
7 Pages

Endothelium Activation during Severe Yellow Fever Triggers an Intense Cytokine-Mediated Inflammatory Response in the Liver Parenchyma

  • Fábio Alves Olímpio,
  • Luiz Fábio Magno Falcão,
  • Marcos Luiz Gaia Carvalho,
  • Jeferson da Costa Lopes,
  • Caio Cesar Henriques Mendes,
  • Arnaldo Jorge Martins Filho,
  • Carlos Augusto Moreira da Silva,
  • Vanessa do Socorro Cabral Miranda,
  • Lais Carneiro dos Santos and
  • Fellipe Souza da Silva Vilacoert
  • + 8 authors

15 January 2022

Yellow fever (YF) is a pansystemic disease caused by the yellow fever virus (YFV), the prototype species of the family Flaviviridae and genus Flavivirus, and has a highly complex host-pathogen relationship, in which endothelial dysfunction reflects v...

  • Review
  • Open Access
2 Citations
3,891 Views
15 Pages

Regulatory Role of Phospholipids in Hepatitis C Virus Replication and Protein Function

  • Anna V. Bulankina,
  • Rebecca M. Richter and
  • Christoph Welsch

15 January 2022

Positive-strand RNA viruses such as hepatitis C virus (HCV) hijack key factors of lipid metabolism of infected cells and extensively modify intracellular membranes to support the viral lifecycle. While lipid metabolism plays key roles in viral partic...

  • Article
  • Open Access
13 Citations
2,877 Views
15 Pages

Avian Macrophage Responses to Virulent and Avirulent Clostridium perfringens

  • Raveendra R. Kulkarni,
  • Carissa Gaghan and
  • Javid Mohammed

15 January 2022

The present study evaluated the avian macrophage responses against Clostridium perfringens that varied in their ability to cause necrotic enteritis in chickens. Strains CP5 (avirulent-netB+), CP1 (virulent-netB+), and CP26 (highly virulent-netB+tpeL+...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Pathogens - ISSN 2076-0817Creative Common CC BY license