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Diagnostics, Volume 14, Issue 1

January-1 2024 - 120 articles

Cover Story: The use of handheld point-of-care (POCUS) systems has increased rapidly throughout emergency care and hospital medicine. Studies of cart-based POCUS systems have shown improvements in patient care, and for specific use cases, handheld POCUS systems using traditional piezoelectric crystals to generate an image have also performed well. Newer non-piezoelectric systems that instead use a chip array to generate images are generally less expensive, but little is known about how these devices perform in daily use conditions in an emergency setting. After one year of continuous use in an emergency department and trauma center, we retrospectively evaluated the performance of a non-piezoelectric handheld POCUS system to characterize its diagnostic performance for emergent and urgent diagnoses. View this paper
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Articles (120)

  • Case Report
  • Open Access
1 Citations
3,830 Views
13 Pages

Diagnostic Methods in Forensic Pathology: Autoptic Findings and Immunohistochemical Study in Cases of Sudden Death Due to a Colloid Cyst of the Third Ventricle

  • Angelo Montana,
  • Francesco Paolo Busardò,
  • Giovanni Tossetta,
  • Gaia Goteri,
  • Pasqualina Castaldo,
  • Giuseppe Basile and
  • Giulia Bambagiotti

The colloid cyst is a non-malignant tumor growth made of a gelatinous material covered by a membrane of epithelial tissue. It is usually located posterior to the foramen of Monro, in the anterior aspect of the third ventricle of the brain. Due to its...

  • Systematic Review
  • Open Access
11 Citations
4,337 Views
18 Pages

Artificial Intelligence in Predicting Microsatellite Instability and KRAS, BRAF Mutations from Whole-Slide Images in Colorectal Cancer: A Systematic Review

  • Theo Guitton,
  • Pierre Allaume,
  • Noémie Rabilloud,
  • Nathalie Rioux-Leclercq,
  • Sébastien Henno,
  • Bruno Turlin,
  • Marie-Dominique Galibert-Anne,
  • Astrid Lièvre,
  • Alexandra Lespagnol and
  • Thierry Pécot
  • + 1 author

Mismatch repair deficiency (d-MMR)/microsatellite instability (MSI), KRAS, and BRAF mutational status are crucial for treating advanced colorectal cancer patients. Traditional methods like immunohistochemistry or polymerase chain reaction (PCR) can b...

  • Review
  • Open Access
12 Citations
3,893 Views
12 Pages

Navigation and Robotics in Interventional Oncology: Current Status and Future Roadmap

  • Georgios Charalampopoulos,
  • Reto Bale,
  • Dimitrios Filippiadis,
  • Bruno C. Odisio,
  • Bradford Wood and
  • Luigi Solbiati

Interventional oncology (IO) is the field of Interventional Radiology that provides minimally invasive procedures under imaging guidance for the diagnosis and treatment of malignant tumors. Sophisticated devices can be utilized to increase standardiz...

  • Article
  • Open Access
30 Citations
6,135 Views
16 Pages

Histopathological Image Diagnosis for Breast Cancer Diagnosis Based on Deep Mutual Learning

  • Amandeep Kaur,
  • Chetna Kaushal,
  • Jasjeet Kaur Sandhu,
  • Robertas Damaševičius and
  • Neetika Thakur

Every year, millions of women across the globe are diagnosed with breast cancer (BC), an illness that is both common and potentially fatal. To provide effective therapy and enhance patient outcomes, it is essential to make an accurate diagnosis as so...

  • Article
  • Open Access
1 Citations
2,551 Views
15 Pages

Application of a 21-Gene Recurrence Score in a Swiss Single-Center Breast Cancer Population: A Comparative Analysis of Treatment Administration before and after TAILORx

  • Elena Diana Chiru,
  • Anton Oseledchyk,
  • Andreas Schoetzau,
  • Christian Kurzeder,
  • Raphael Mosimann,
  • Marcus Vetter and
  • Cvetka Grašič Kuhar

In patients with hormone receptor positive, human epidermal receptor 2 negative (HR+/HER2−) negative breast cancer (BC), the TAILORx study showed the benefit of adding chemotherapy (CHT) to endocrine therapy (ET) in a subgroup of patients under...

  • Article
  • Open Access
4 Citations
2,089 Views
15 Pages

Gaining the ability to audit the behavior of deep learning (DL) denoising models is of crucial importance to prevent potential hallucinations and adversarial clinical consequences. We present a preliminary version of AntiHalluciNet, which is designed...

  • Article
  • Open Access
2 Citations
2,899 Views
13 Pages

Explaining the Elusive Nature of a Well-Defined Threshold for Blood Transfusion in Advanced Epithelial Ovarian Cancer Cytoreductive Surgery

  • Alexandros Laios,
  • Evangelos Kalampokis,
  • Marios-Evangelos Mamalis,
  • Amudha Thangavelu,
  • Yong Sheng Tan,
  • Richard Hutson,
  • Sarika Munot,
  • Tim Broadhead,
  • David Nugent and
  • Georgios Theophilou
  • + 2 authors

There is no well-defined threshold for intra-operative blood transfusion (BT) in advanced epithelial ovarian cancer (EOC) surgery. To address this, we devised a Machine Learning (ML)-driven prediction algorithm aimed at prompting and elucidating a co...

  • Article
  • Open Access
1 Citations
2,231 Views
14 Pages

Analysis of Hand Function, Upper Limb Disability, and Its Relationship with Peripheral Vascular Alterations in Raynaud’s Phenomenon

  • Rosa Mª Tapia-Haro,
  • Mª Carmen García-Ríos,
  • Adelaida Mª Castro-Sánchez,
  • Sonia Toledano-Moreno,
  • Antonio Casas-Barragán and
  • Mª Encarnación Aguilar-Ferrándiz

This study aimed to compare vascular involvement, hand functionality, and upper limb disability between Raynaud’s phenomenon participants and controls. Also, we analyzed the relationships between vascular impairment, mobility, and strength with...

  • Article
  • Open Access
2,177 Views
17 Pages

Differentiation of Salivary Gland and Salivary Gland Tumor Tissue via Raman Imaging Combined with Multivariate Data Analysis

  • Miriam C. Bassler,
  • Mona Knoblich,
  • Elena Gerhard-Hartmann,
  • Ashutosh Mukherjee,
  • Almoatazbellah Youssef,
  • Rudolf Hagen,
  • Lukas Haug,
  • Miguel Goncalves,
  • Agmal Scherzad and
  • Manuel Stöth
  • + 5 authors

Salivary gland tumors (SGTs) are a relevant, highly diverse subgroup of head and neck tumors whose entity determination can be difficult. Confocal Raman imaging in combination with multivariate data analysis may possibly support their correct classif...

  • Article
  • Open Access
4 Citations
4,028 Views
12 Pages

In this study, we evaluated the effectiveness of a single-dose oral pilocarpine administration on tear film (TF), as well as dry eye and dry mouth symptoms, in 53 eyes of 27 Sjögren syndrome (SS) patients who were experiencing dry mouth. To eval...

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Diagnostics - ISSN 2075-4418