Next Article in Journal
GRB10 and E2F3 as Diagnostic Markers of Osteoarthritis and Their Correlation with Immune Infiltration
Previous Article in Journal
Triple Metachronous Malignancies with Thyroid Involvement: A Brief Overview of Five Case Reports over 20 Years of Institutional Experience
Open AccessArticle

Simultaneous Measurement of Gastric Emptying of a Soup Test Meal Using MRI and Gamma Scintigraphy

1
Radiologic Sciences, Allied Health Sciences, Kuwait University, 90805 Sulaibekhat, Kuwait City, Kuwait
2
Nottingham Digestive Diseases Centre and National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham NG7 2UH, UK
3
Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham NG7 2QX, UK
4
Medical Physics and Clinical Engineering, Nottingham University Hospitals NHS Trust, Nottingham NG7 2UH, UK
5
Diagnostic Radiology, Faculty of Applied Medical Science, King Abdulaziz University, 21589 Jeddah, Saudi Arabia
6
Radiological Sciences, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK
*
Author to whom correspondence should be addressed.
Diagnostics 2020, 10(3), 170; https://doi.org/10.3390/diagnostics10030170
Received: 29 January 2020 / Revised: 13 March 2020 / Accepted: 17 March 2020 / Published: 22 March 2020
(This article belongs to the Section Medical Imaging)
Measurement of gastric emptying is of clinical value for a range of conditions. Gamma scintigraphy (GS) has an established role, but the use of magnetic resonance imaging (MRI) has recently increased. Previous comparison studies between MRI and GS showed good correlation, but were performed on separate study days. In this study, the modalities were alternated rapidly allowing direct comparison with no intra-individual variability confounds. Twelve healthy participants consumed 400 g of Technetium-99m (99mTc)-labelled soup test meal (204 kcal) and were imaged at intervals for 150 min, alternating between MRI and GS. The time to empty half of the stomach contents (T1/2) and retention rate (RR) were calculated and data correlated. The average T1/2 was similar for MRI (44 ± 6 min) and GS (35 ± 4 min) with a moderate but significant difference between the two modalities (p < 0.004). The individual T1/2 values were measured, and MRI and GS showed a good positive correlation (r = 0.95, p < 0.0001), as well as all the RRs at each time point up to 120 min. Gastric emptying was measured for the first time by MRI and GS on the same day. This may help with translating the use of this simple meal, known to elicit reliable, physiological, and pathological gastrointestinal motor, peptide, and appetite responses. View Full-Text
Keywords: magnetic resonance imaging; stomach; validation; volumes; half emptying; activity magnetic resonance imaging; stomach; validation; volumes; half emptying; activity
Show Figures

Figure 1

MDPI and ACS Style

Khalaf, A.; Hoad, C.L.; Blackshaw, E.; Alyami, J.; Spiller, R.C.; Gowland, P.A.; Vinayaka-Moorthy, V.; Perkins, A.C.; Moran, G.W.; Marciani, L. Simultaneous Measurement of Gastric Emptying of a Soup Test Meal Using MRI and Gamma Scintigraphy. Diagnostics 2020, 10, 170. https://doi.org/10.3390/diagnostics10030170

AMA Style

Khalaf A, Hoad CL, Blackshaw E, Alyami J, Spiller RC, Gowland PA, Vinayaka-Moorthy V, Perkins AC, Moran GW, Marciani L. Simultaneous Measurement of Gastric Emptying of a Soup Test Meal Using MRI and Gamma Scintigraphy. Diagnostics. 2020; 10(3):170. https://doi.org/10.3390/diagnostics10030170

Chicago/Turabian Style

Khalaf, Asseel; Hoad, Caroline L.; Blackshaw, Elaine; Alyami, Jaber; Spiller, Robin C.; Gowland, Penny A.; Vinayaka-Moorthy, Vidhiya; Perkins, Alan C.; Moran, Gordon W.; Marciani, Luca. 2020. "Simultaneous Measurement of Gastric Emptying of a Soup Test Meal Using MRI and Gamma Scintigraphy" Diagnostics 10, no. 3: 170. https://doi.org/10.3390/diagnostics10030170

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Search more from Scilit
 
Search
Back to TopTop