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Life, Volume 10, Issue 8

2020 August - 35 articles

Cover Story: Extracellular vesicles (EVs) are lipid bilayered, nanoscale structures that are released into the extracellular space by living cells and, thus, represent a bona fide secretion system. In bacteria, the study of EVs’ composition, biogenesis mechanisms, biological roles, and possible biotechnological applications have recently become hot topics. Here, we present a general overview of the most relevant findings in EVs released by Gram-negative bacteria, focusing our attention on bacteria from the phylum Cyanobacteria, in which the study of EVs has been largely overlooked. As Cyanobacteria are important primary producers with unique cell wall features, future studies in cyanobacterial EVs may shed light on several pending aspects of EV biology, as well as clarify unsolved traits of cyanobacterial physiology. View this paper
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Articles (35)

  • Review
  • Open Access
38 Citations
5,887 Views
20 Pages

8 August 2020

Aβ, IAPP, α-synuclein, and prion proteins belong to the amyloidogenic intrinsically disordered proteins’ family; indeed, they lack well defined secondary and tertiary structures. It is generally acknowledged that they are involved, r...

  • Review
  • Open Access
9 Citations
5,606 Views
16 Pages

7 August 2020

Proteins are crucial players of biological interactions within and between the organisms and thus it is important to understand the role of proteins in successful partnerships, such as insect vectors and their plant viruses. Proteomic approaches have...

  • Article
  • Open Access
11 Citations
17,689 Views
11 Pages

6 August 2020

Rounded shoulder posture (RSP) causes an imbalance of the adjacent joints due to the malalignment of the shoulder joint, and thus affects the strength of the muscles surrounding the shoulder. This study aimed to investigate the effect of rounded shou...

  • Review
  • Open Access
177 Citations
14,601 Views
37 Pages

Seaweed’s Bioactive Candidate Compounds to Food Industry and Global Food Security

  • Adriana Leandro,
  • Diana Pacheco,
  • João Cotas,
  • João C. Marques,
  • Leonel Pereira and
  • Ana M. M. Gonçalves

6 August 2020

The world population is continuously growing, so it is important to keep producing food in a sustainable way, especially in a way that is nutritious and in a sufficient quantity to overcome global needs. Seaweed grows, and can be cultivated, in seawa...

  • Article
  • Open Access
7 Citations
3,850 Views
19 Pages

Evaluation of GammaH2AX in Buccal Cells as a Molecular Biomarker of DNA Damage in Alzheimer’s Disease in the AIBL Study of Ageing

  • Mohammad Sabbir Siddiqui,
  • Maxime Francois,
  • Stephanie Rainey-Smith,
  • Ralph Martins,
  • Colin L. Masters,
  • David Ames,
  • Christopher C. Rowe,
  • Lance S. Macaulay,
  • Michael F. Fenech and
  • Wayne R. Leifert

6 August 2020

In response to double-stranded breaks (DSBs) in chromosomal DNA, H2AX (a member of histone H2A family) becomes phosphorylated to form γH2AX. Although increased levels of γH2AX have been reported in the neuronal nuclei of Alzheimer’s disease (AD) pati...

  • Article
  • Open Access
6 Citations
3,924 Views
10 Pages

6 August 2020

Introduction of alien species is a well-known threat to biodiversity. Where newly introduced, alien species may pose a risk for the local ecological community by competing for resources or by introducing pathogens. Sylvilagus floridanus is an America...

  • Article
  • Open Access
8 Citations
4,092 Views
14 Pages

Prevalence of Older Adult Disability and Primary Health Care Responsiveness in Low-Income Communities

  • Giovana Montoro Pazzini Watfe,
  • Lais Fajersztajn,
  • Euler Ribeiro,
  • Paulo Rossi Menezes and
  • Marcia Scazufca

5 August 2020

In Brazil and in most low- and middle-income countries (LMICs), information about how prepared the health care system is for the rapid aging of the population is scarce. We investigated the prevalence of disability and areas of life affected by disab...

  • Article
  • Open Access
20 Citations
5,774 Views
17 Pages

The Ancient History of Peptidyl Transferase Center Formation as Told by Conservation and Information Analyses

  • Francisco Prosdocimi,
  • Gabriel S. Zamudio,
  • Miryam Palacios-Pérez,
  • Sávio Torres de Farias and
  • Marco V. José

5 August 2020

The peptidyl transferase center (PTC) is the catalytic center of the ribosome and forms part of the 23S ribosomal RNA. The PTC has been recognized as the earliest ribosomal part and its origins embodied the First Universal Common Ancestor (FUCA). The...

  • Article
  • Open Access
6 Citations
4,253 Views
13 Pages

An Another Protocol to Make Sulfur Embedded Ultrathin Sections of Extraterrestrial Small Samples

  • Takaaki Noguchi,
  • Minako Takase,
  • Rikako Matsumoto,
  • Yoko Kebukawa,
  • Hiroki Suga,
  • Masashi Kondo,
  • Yoshio Takahashi,
  • Yasuo Takeichi and
  • Hikaru Yabuta

5 August 2020

Another protocol to make sulfur embedded ultrathin sections was developed for STXM–XANES, AFM–IR and TEM analyses of organic materials in small extraterrestrial samples. Polymerized liquid sulfur—instead of low-viscosity liquid sulf...

  • Article
  • Open Access
4 Citations
5,729 Views
16 Pages

First mtDNA Sequences and Body Measurements for Rattus norvegicus from the Mediterranean Island of Cyprus

  • Eleftherios Hadjisterkotis,
  • George Konstantinou,
  • Daria Sanna,
  • Monica Pirastru and
  • Paolo Mereu

5 August 2020

Invasive species are the primary driver of island taxa extinctions and, among them, those belonging to the genus Rattus are considered as the most damaging. The presence of black rat (Rattus rattus) on Cyprus has long been established, while that of...

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Life - ISSN 2075-1729