Table of Contents
Toxins, Volume 8, Issue 1 (January 2016)
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Cover Story (view full-size image) Box jelly tentacles eject thousands of microscopic, venom-filled tubules during stings that cause [...] Read more. Box jelly tentacles eject thousands of microscopic, venom-filled tubules during stings that cause more deaths each year than sharks. Still, there is intense debate about the most effective first-aid measures. A major impediment to progress has been the lack of reproducible experimental models. In this issue of Toxins, Yanagihara and colleagues introduce affordable and accessible human tissue models for evaluating the effectiveness of first aids. The team developed an array of robust, reproducible assays to compare the effectiveness of measures employed by emergency caregivers. Results demonstrated that vinegar rinse irreversibly inhibits additional tentacle stinging, and that heat application reduced already-injected venom activity. New Sting No More® technologies were even more effective. View this article.