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Nutrients, Volume 13, Issue 1

January 2021 - 280 articles

Cover Story: This narrative review provides an overview of the effect of coffee brew; its by-products; and its components on the gastrointestinal mucosa (mainly involved in permeability, secretion, and proliferation), the neural and non-neural components of the gut wall responsible for its motor function, and the brain–gut axis. Despite in vitro, in vivo, and epidemiological studies having shown that coffee may exert multiple effects on the digestive tract, including antioxidant, anti-inflammatory, and antiproliferative effects on the mucosa, and pro-motility effects on the external muscle layers, much is still surprisingly unknown. Further studies are needed to understand the mechanisms of action of certain health-promoting properties of coffee on the gastrointestinal tract and to transfer this knowledge to the industry to develop functional foods to improve the gastrointestinal and brain–gut axis health. View this paper
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Articles (280)

  • Article
  • Open Access
20 Citations
12,586 Views
11 Pages

Tandem Breastfeeding: A Descriptive Analysis of the Nutritional Value of Milk When Feeding a Younger and Older Child

  • Elena Sinkiewicz-Darol,
  • Urszula Bernatowicz-Łojko,
  • Katarzyna Łubiech,
  • Iwona Adamczyk,
  • Magdalena Twarużek,
  • Barbara Baranowska,
  • Krzysztof Skowron and
  • Diane L. Spatz

19 January 2021

Breastfeeding is a gold standard of feeding of newborns and infants. Tandem breastfeeding (TBF) is feeding two children of different ages at the same time. The knowledge about the composition of human milk in prolonged lactation is still scarce. Milk...

  • Review
  • Open Access
36 Citations
12,694 Views
18 Pages

Strategies for Reducing Salt and Sugar Intakes in Individuals at Increased Cardiometabolic Risk

  • Valentina Ponzo,
  • Marianna Pellegrini,
  • Paola Costelli,
  • Laura Vázquez-Araújo,
  • Lucía Gayoso,
  • Chiara D’Eusebio,
  • Ezio Ghigo and
  • Simona Bo

19 January 2021

Non-communicable diseases (NCDs) are the first causes of death worldwide. Reduction in the dietary intake of salt and sugars is important lifestyle advice that is useful for NCD prevention. However, the simple recommendations of reducing salt and sug...

  • Article
  • Open Access
8 Citations
5,917 Views
12 Pages

Protective Effects of Medicinal Plant Decoctions on Macrophages in the Context of Atherosclerosis

  • Eloïse Checkouri,
  • Stéphane Ramin-Mangata,
  • Nicolas Diotel,
  • Wildriss Viranaicken,
  • Claude Marodon,
  • Franck Reignier,
  • Christine Robert-Da Silva and
  • Olivier Meilhac

19 January 2021

Atherosclerosis is a hallmark of most cardiovascular diseases. The implication of macrophages in this pathology is widely documented, notably for their contribution to lipid accumulation within the arterial wall, associated with oxidative stress and...

  • Article
  • Open Access
36 Citations
7,545 Views
16 Pages

A Phase IIb Randomized Controlled Trial Investigating the Effects of Tocotrienol-Rich Vitamin E on Diabetic Kidney Disease

  • Yan Yi Koay,
  • Gerald Chen Jie Tan,
  • Sonia Chew Wen Phang,
  • J-Ian Ho,
  • Pei Fen Chuar,
  • Loon Shin Ho,
  • Badariah Ahmad and
  • Khalid Abdul Kadir

18 January 2021

Diabetic kidney disease (DKD) is a debilitating complication of diabetes, which develops in 40% of the diabetic population and is responsible for up to 50% of end-stage renal disease (ESRD). Tocotrienols have shown to be a potent antioxidant, anti-in...

  • Article
  • Open Access
12 Citations
9,774 Views
13 Pages

Association of Testosterone-Related Dietary Pattern with Testicular Function among Adult Men: A Cross-Sectional Health Screening Study in Taiwan

  • Adi-Lukas Kurniawan,
  • Chien-Yeh Hsu,
  • Jane C-J Chao,
  • Rathi Paramastri,
  • Hsiu-An Lee,
  • Pao-Chin Lai,
  • Nan-Chen Hsieh and
  • Shu-Fang Vivienne Wu

18 January 2021

Diets could play an important role in testicular function, but studies on how adherence to the dietary patterns influences human testicular function in Asian countries are scarce. Herein, we examined the association between testosterone-related dieta...

  • Article
  • Open Access
4 Citations
5,492 Views
15 Pages

Ayurvedic Herbal Preparation Supplementation Does Not Improve Metabolic Health in Impaired Glucose Tolerance Subjects; Observations from a Randomised Placebo Controlled Trial

  • Diederik Esser,
  • Juri Matualatupauw,
  • Ric C. H. de Vos,
  • Ron Wehrens,
  • Jos van der Stappen,
  • Ingrid van der Meer and
  • Lydia A. Afman

18 January 2021

The increased usage of alternative Ayurvedic treatments as potential health-beneficial therapies emphasizes the importance of studying its efficacy in sound placebo-controlled intervention trials. An example of such a traditional Ayurvedic herbal pre...

  • Review
  • Open Access
6 Citations
5,721 Views
12 Pages

Diet and PPARG2 Pro12Ala Polymorphism Interactions in Relation to Cancer Risk: A Systematic Review

  • Lieu Tran,
  • Gerd Bobe,
  • Gayatri Arani,
  • Yang Zhang,
  • Zhenzhen Zhang,
  • Jackilen Shannon and
  • Yumie Takata

18 January 2021

Peroxisome proliferator-activated receptor-γ2 gene Pro12Ala allele polymorphism (PPARG2 Pro12Ala; rs1801282) has been linked to both cancer risk and dietary factors. We conducted the first systematic literature review of studies published befor...

  • Article
  • Open Access
15 Citations
3,678 Views
15 Pages

Association of Circulating Trimethylamine N-Oxide and Its Dietary Determinants with the Risk of Kidney Graft Failure: Results of the TransplantLines Cohort Study

  • Jose L. Flores-Guerrero,
  • Maryse C. J. Osté,
  • Paula B. Baraldi,
  • Margery A. Connelly,
  • Erwin Garcia,
  • Gerjan Navis,
  • Stephan J. L. Bakker and
  • Robin P. F. Dullaart

18 January 2021

Background. Due to the critical shortage of kidneys for transplantation, the identification of modifiable factors related to graft failure is highly desirable. The role of trimethylamine-N-oxide (TMAO) in graft failure remains undetermined. Here, we...

  • Article
  • Open Access
27 Citations
7,401 Views
14 Pages

18 January 2021

NutritionDay (nDay) is a project established by the Medical University of Vienna and the European Society for Clinical Nutrition and Metabolism (ESPEN) to audit the nutritional status of hospitalized patients and nursing home residents. This study ai...

  • Article
  • Open Access
8 Citations
7,163 Views
15 Pages

18 January 2021

In an aging society, preventing dysfunction and restoring function of the locomotive organs are necessary for long-term quality of life. Few interventional studies have investigated supplementation for locomotive syndrome. Additionally, very few inte...

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Nutrients - ISSN 2072-6643