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Viruses, Volume 14, Issue 3

March 2022 - 206 articles

Cover Story: Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne nairovirus that causes hemorrhagic fever in humans. The CCHFV nucleoprotein (NP) is the antigen most used for serological screening of CCHFV infection of animals and humans. In this study, we sought to identify epitopes on the NP molecule. We found that the amino acids at positions 161–320 might include dominant epitopes, whereas IgG cross-reactivity to Nairobi sheep disease virus, which is another nairovirus, was limited. Using CCHFV NP-derived synthetic peptides, some potential epitope peptides were also identified. Our results provide useful information to improve NP-based antibody detection assays as well as antigen detection tests relying on anti-NP monoclonal antibodies. View this paper
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Articles (206)

  • Article
  • Open Access
3 Citations
4,495 Views
12 Pages

Protection of Ducklings from Duck Hepatitis A Virus Infection with ELPylated Duck Interferon-α

  • Yongjuan Wang,
  • Yanli Guo,
  • Haowei Wang,
  • Zhi Wu,
  • Weiming Hong,
  • Huaichang Sun and
  • Shanyuan Zhu

18 March 2022

Duck viral hepatitis type I (DVH I) is a lethal disease in ducklings caused by duck hepatitis A virus (DHAV). Although the commercial vaccine is available for vaccination of one-day-old ducklings or breeder ducks, the disease is still prevalent due t...

  • Article
  • Open Access
4 Citations
4,213 Views
22 Pages

Infectious Salmon Anemia Virus Infectivity Is Determined by Multiple Segments with an Important Contribution from Segment 5

  • Matías Cárdenas,
  • Sofía Michelson,
  • Daniel R. Pérez,
  • Margarita Montoya,
  • Jorge Toledo,
  • Yesseny Vásquez-Martínez and
  • Marcelo Cortez-San Martin

18 March 2022

Infectious salmon anemia virus (ISAV) is the etiological agent of infectious salmon anemia. It belongs to the genus isavirus, one of the genera of the Orthomyxoviridae family, as does Influenzavirus A. The ISAV genome comprises eight negative-sense s...

  • Review
  • Open Access
6 Citations
5,405 Views
14 Pages

18 March 2022

Prion diseases are transmissible protein misfolding disorders that occur in animals and humans where the endogenous prion protein, PrPC, undergoes a conformational change into self-templating aggregates termed PrPSc. Formation of PrPSc in the central...

  • Article
  • Open Access
10 Citations
4,064 Views
15 Pages

Genomic Characterisation of UFJF_PfDIW6: A Novel Lytic Pseudomonas fluorescens-Phage with Potential for Biocontrol in the Dairy Industry

  • Humberto Moreira Hungaro,
  • Pedro Marcus Pereira Vidigal,
  • Edilane Cristina do Nascimento,
  • Felipe Gomes da Costa Oliveira,
  • Marco Túlio Pardini Gontijo and
  • Maryoris Elisa Soto Lopez

17 March 2022

In this study, we have presented the genomic characterisation of UFJF_PfDIW6, a novel lytic Pseudomonas fluorescens-phage with potential for biocontrol in the dairy industry. This phage showed a short linear double-stranded DNA genome (~42 kb) with a...

  • Article
  • Open Access
6 Citations
2,853 Views
24 Pages

Sex-Dependent Differences in Predictive Value of the C2HEST Score in Subjects with COVID-19—A Secondary Analysis of the COLOS Study

  • Piotr Rola,
  • Adrian Doroszko,
  • Małgorzata Trocha,
  • Katarzyna Giniewicz,
  • Krzysztof Kujawa,
  • Marek Skarupski,
  • Damian Gajecki,
  • Jakub Gawryś,
  • Tomasz Matys and
  • Ewa Szahidewicz-Krupska
  • + 17 authors

17 March 2022

Background: Since the outbreak of the COVID-19 pandemic, a growing number of evidence suggests that COVID-19 presents sex-dependent differences in clinical course and outcomes. Nevertheless, there is still an unmet need to stratify the risk for poor...

  • Article
  • Open Access
12 Citations
3,724 Views
12 Pages

Insights into Gene Transcriptional Regulation of Kayvirus Bacteriophages Obtained from Therapeutic Mixtures

  • Sara Arroyo-Moreno,
  • Colin Buttimer,
  • Francesca Bottacini,
  • Nina Chanishvili,
  • Paul Ross,
  • Colin Hill and
  • Aidan Coffey

17 March 2022

Bacteriophages (phages) of the genus Kayvirus of Staphylococcus aureus are promising agents for therapeutic applications. In this study, we isolated Kayvirus phages, SAM1 and SAM2, from the Fersisi commercial phage cocktail (George Eliava Institute,...

  • Case Report
  • Open Access
23 Citations
4,430 Views
10 Pages

SARS-CoV-2 and Influenza Virus Co-Infection Cases Identified through ILI/SARI Sentinel Surveillance: A Pan-India Report

  • Neeraj Aggarwal,
  • Varsha Potdar,
  • Neetu Vijay,
  • Labanya Mukhopadhyay,
  • Biswajyoti Borkakoty,
  • S. Manjusree,
  • Manohar Lal Choudhary,
  • Deepika Chowdhury,
  • Riya Verma and
  • Sumit Dutt Bhardwaj
  • + 4 authors

17 March 2022

SARS-CoV-2/influenza virus co-infection studies have focused on hospitalized patients who usually had grave sequelae. Here, we report SARS-CoV-2/influenza virus co-infection cases from both community and hospital settings reported through integrated...

  • Article
  • Open Access
2 Citations
2,809 Views
15 Pages

Identifying Country-Level Risk Factors for the Spread of COVID-19 in Europe Using Machine Learning

  • Serafeim Moustakidis,
  • Christos Kokkotis,
  • Dimitrios Tsaopoulos,
  • Petros Sfikakis,
  • Sotirios Tsiodras,
  • Vana Sypsa,
  • Theoklis E. Zaoutis and
  • Dimitrios Paraskevis

17 March 2022

Coronavirus disease 2019 (COVID-19) has resulted in approximately 5 million deaths around the world with unprecedented consequences in people’s daily routines and in the global economy. Despite vast increases in time and money spent on COVID-19...

  • Article
  • Open Access
26 Citations
4,892 Views
14 Pages

Molecular Epidemiology of SARS-CoV-2 in Tunisia (North Africa) through Several Successive Waves of COVID-19

  • Anissa Chouikha,
  • Wasfi Fares,
  • Asma Laamari,
  • Sondes Haddad-Boubaker,
  • Zeineb Belaiba,
  • Kais Ghedira,
  • Wafa Kammoun Rebai,
  • Kaouther Ayouni,
  • Marwa Khedhiri and
  • Samar Ben Halima
  • + 14 authors

17 March 2022

Documenting the circulation dynamics of SARS-CoV-2 variants in different regions of the world is crucial for monitoring virus transmission worldwide and contributing to global efforts towards combating the pandemic. Tunisia has experienced several wa...

  • Article
  • Open Access
20 Citations
5,232 Views
14 Pages

Expanding the Medfly Virome: Viral Diversity, Prevalence, and sRNA Profiling in Mass-Reared and Field-Derived Medflies

  • Luis Hernández-Pelegrín,
  • Ángel Llopis-Giménez,
  • Cristina Maria Crava,
  • Félix Ortego,
  • Pedro Hernández-Crespo,
  • Vera I. D. Ros and
  • Salvador Herrero

17 March 2022

The Mediterranean fruit fly (medfly), Ceratitis capitata, is an agricultural pest of a wide range of fruits. The advent of high-throughput sequencing has boosted the discovery of RNA viruses infecting insects. In this article, we aim to characterize...

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Viruses - ISSN 1999-4915