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Viruses, Volume 14, Issue 11

November 2022 - 275 articles

Cover Story: Bacteriophages are viruses of bacteria, for which molecular mechanisms of host-hijacking remain poorly explored. In this work, we apply omics technologies—transcriptomics and proteomics—to temporally resolve transcription and protein synthesis during the T4 phage infection of E. coli on a molecular level. For E. coli, we observed degradation of its transcripts and the preservation of the proteome. For T4 phage, the correlation between the transcriptome and proteome reveals specific T4 phage mRNAs and proteins that are temporally decoupled, suggesting post-transcriptional and translational regulation mechanisms. Our tool, POTATO4, provides access to these first comprehensive insights into the gene expression patterns of T4 phage infection of E. coli. View this paper
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Articles (275)

  • Article
  • Open Access
12 Citations
3,130 Views
13 Pages

Epidemiological Aspects of Equid Herpesvirus-Associated Myeloencephalopathy (EHM) Outbreaks

  • Eva Klouth,
  • Yury Zablotski,
  • Jessica L. Petersen,
  • Marco de Bruijn,
  • Gittan Gröndahl,
  • Susanne Müller and
  • Lutz S. Goehring

21 November 2022

Equid Herpesvirus Myeloencephalopathy (EHM) is a multifactorial disease following an EHV-1 infection in Equidae. We investigated a total of 589 horses on 13 premises in Europe in search of risk factors for the development of EHM. We found that fever...

  • Review
  • Open Access
11 Citations
5,731 Views
18 Pages

21 November 2022

Influenza A virus is a respiratory pathogen that is responsible for regular epidemics and occasional pandemics that result in substantial damage to life and the economy. The yearly reformulation of trivalent or quadrivalent flu vaccines encompassing...

  • Article
  • Open Access
7 Citations
5,079 Views
13 Pages

Impact of Hepatitis B Virus Infection, Non-alcoholic Fatty Liver Disease, and Hepatitis C Virus Co-infection on Liver-Related Death among People Tested for Hepatitis B Virus in British Columbia: Results from a Large Longitudinal Population-Based Cohort Study

  • Jean Damascene Makuza,
  • Dahn Jeong,
  • Mawuena Binka,
  • Prince Asumadu Adu,
  • Georgine Cua,
  • Amanda Yu,
  • Héctor Alexander Velásquez García,
  • Maria Alvarez,
  • Stanley Wong and
  • Sofia Bartlett
  • + 5 authors

21 November 2022

Data on the contribution of hepatitis B virus (HBV) infection and related comorbidities to liver-related mortality in Canada are limited. We assessed the concurrent impact of HBV infection, non-alcoholic fatty liver disease (NAFLD), and hepatitis C v...

  • Article
  • Open Access
2 Citations
2,709 Views
17 Pages

Novel RT-PCR Using Sugar Chain-Immobilized Gold-Nanoparticles Correlates Patients’ Symptoms: The Follow-Up Study of COVID-19 Hospitalized Patients

  • Takashi Kajiya,
  • Hayate Sawayama,
  • Eriko Arima,
  • Mika Okamoto,
  • Masanori Baba,
  • Masaaki Toyama,
  • Kosuke Okuya,
  • Makoto Ozawa,
  • Nobuhiko Atsuchi and
  • Junichiro Nishi
  • + 1 author

21 November 2022

Background: The transmissible capacity and toxicity of SARS-CoV-2 variants are continually changing. We report here the follow-up study of hospitalized COVID-19 patients from 2020 to 2022. It is known that the PCR diagnosis for hospitalized patients...

  • Review
  • Open Access
77 Citations
22,111 Views
19 Pages

Immune-Mediated Pathogenesis in Dengue Virus Infection

  • Arshi Khanam,
  • Hector Gutiérrez-Barbosa,
  • Kirsten E. Lyke and
  • Joel V. Chua

21 November 2022

Dengue virus (DENV) infection is one of the major public health concerns around the globe, especially in the tropical regions of the world that contribute to 75% percent of dengue cases. While the majority of DENV infections are mild or asymptomatic,...

  • Article
  • Open Access
4 Citations
3,892 Views
16 Pages

A Characterization and an Evolutionary and a Pathogenicity Analysis of Reassortment H3N2 Avian Influenza Virus in South China in 2019–2020

  • Tengfei Liu,
  • Yuhao Huang,
  • Shumin Xie,
  • Lingyu Xu,
  • Junhong Chen,
  • Wenbao Qi,
  • Ming Liao and
  • Weixin Jia

21 November 2022

Seasonal H3N2 influenza virus has always been a potential threat to public health. The reassortment of the human and avian H3N2 influenza viruses has resulted in major influenza outbreaks, which have seriously damaged human life and health. To assess...

  • Article
  • Open Access
4 Citations
2,826 Views
12 Pages

Change in Nutritional and Biochemical Status in People Living with HIV-1 on Antiretroviral Therapy

  • Ranilda Gama de Souza,
  • Sandra Souza Lima,
  • Andresa Corrêa Pinto,
  • Jacqueline Silva Souza,
  • Tuane Carolina Ferreira Moura,
  • Ednelza da Silva Graça Amoras,
  • Luiz Fernando Almeida Machado,
  • João Farias Guerreiro,
  • Antonio Carlos Rosário Vallinoto and
  • Maria Alice Freitas Queiroz
  • + 1 author

20 November 2022

Antiretroviral therapy (ART) improves the quality of life of people living with HIV-1 (PLHIV) and reduces the mortality rate, but some individuals may develop metabolic abnormalities. This study evaluated changes in the nutritional status and biochem...

  • Article
  • Open Access
13 Citations
3,160 Views
27 Pages

Discovery, Genomic Sequence Characterization and Phylogenetic Analysis of Novel RNA Viruses in the Turfgrass Pathogenic Colletotrichum spp. in Japan

  • Islam Hamim,
  • Syun-ichi Urayama,
  • Osamu Netsu,
  • Akemi Tanaka,
  • Tsutomu Arie,
  • Hiromitsu Moriyama and
  • Ken Komatsu

20 November 2022

Turfgrass used in various areas of the golf course has been found to present anthracnose disease, which is caused by Colletotrichum spp. To obtain potential biological agents, we identified four novel RNA viruses and obtained full-length viral genome...

  • Article
  • Open Access
2 Citations
2,965 Views
9 Pages

Comparisons of Viral Etiology and Outcomes of Hepatocellular Carcinoma Undergoing Liver Resection between Taiwan and Vietnam

  • Song-Huy Nguyen-Dinh,
  • Wei-Feng Li,
  • Yueh-Wei Liu,
  • Chih-Chi Wang,
  • Yen-Hao Chen,
  • Jing-Houng Wang and
  • Chao-Hung Hung

20 November 2022

Epidemiologic data have suggested that etiologic variations of hepatocellular carcinoma (HCC) exist in different geographic areas, and might be associated with different outcomes. We compared the viral etiology, clinicopathological characteristics an...

  • Article
  • Open Access
6 Citations
2,717 Views
12 Pages

Recent Information on Pan-Genotypic Direct-Acting Antiviral Agents for HCV in Chronic Kidney Disease

  • Fabrizio Fabrizi,
  • Federica Tripodi,
  • Roberta Cerutti,
  • Luca Nardelli,
  • Carlo M. Alfieri,
  • Maria F. Donato and
  • Giuseppe Castellano

20 November 2022

Background: Hepatitis C virus (HCV) is still common in patients with chronic kidney disease. It has been recently discovered that chronic HCV is a risk factor for increased incidence of CKD in the adult general population. According to a systematic r...

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Viruses - ISSN 1999-4915