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Marine Drugs, Volume 18, Issue 12

December 2020 - 78 articles

Cover Story: The extract of a Pseudosuberites sp. sponge provided three new aryl alkaloids named suberitamides A–C. Assignment of the relative configuration of the four contiguous stereogenic centers in the conformationally flexible oxolane ring in suberitamide A was accomplished using a variety of contemporary NMR techniques. These included J-based methodologies that employed new NMR experiments for the accurate determination of heteronuclear coupling constants between protons and nonprotonated carbons. The ubiquitin ligase Cbl-b is an attractive potential target for immune system modulation, and suberitamides A and B inhibited autoubiquitination of Cbl-b at low micromolar concentrations. View this paper.
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Articles (78)

  • Article
  • Open Access
18 Citations
5,340 Views
18 Pages

Proteomic Analysis of the Venom of Jellyfishes Rhopilema esculentum and Sanderia malayensis

  • Thomas C. N. Leung,
  • Zhe Qu,
  • Wenyan Nong,
  • Jerome H. L. Hui and
  • Sai Ming Ngai

21 December 2020

Venomics, the study of biological venoms, could potentially provide a new source of therapeutic compounds, yet information on the venoms from marine organisms, including cnidarians (sea anemones, corals, and jellyfish), is limited. This study identif...

  • Review
  • Open Access
35 Citations
10,938 Views
123 Pages

Bioactive Compounds from Marine Heterobranchs

  • Conxita Avila and
  • Carlos Angulo-Preckler

21 December 2020

The natural products of heterobranch molluscs display a huge variability both in structure and in their bioactivity. Despite the considerable lack of information, it can be observed from the recent literature that this group of animals possesses an a...

  • Review
  • Open Access
101 Citations
10,630 Views
18 Pages

The Structural Characteristics of Seaweed Polysaccharides and Their Application in Gel Drug Delivery Systems

  • Haowei Zhong,
  • Xiaoran Gao,
  • Cui Cheng,
  • Chun Liu,
  • Qiaowen Wang and
  • Xiao Han

21 December 2020

In recent years, researchers across various fields have shown a keen interest in the exploitation of biocompatible natural polymer materials, especially the development and application of seaweed polysaccharides. Seaweed polysaccharides are a multi-c...

  • Article
  • Open Access
72 Citations
9,292 Views
26 Pages

21 December 2020

In recent years, research on natural products has gained considerable attention, particularly in the cosmetic industry, which is looking for new bio-active and biodegradable molecules. In this study, cosmetic properties of cyanobacteria and red macro...

  • Article
  • Open Access
26 Citations
3,720 Views
22 Pages

21 December 2020

In recent years, due to an expansion of antibiotic-resistant microorganisms, there has been growing interest in biodegradable and antibacterial polymers that can be used in selected biomedical applications. The present work describes the synthesis of...

  • Article
  • Open Access
8 Citations
4,596 Views
21 Pages

21 December 2020

The discovery of new secondary metabolites from natural origins has become more challenging in natural products research. Different approaches have been applied to target the isolation of new bioactive metabolites from plant extracts. In this study,...

  • Article
  • Open Access
8 Citations
4,538 Views
9 Pages

Inhibition of Biofilm Formation by Modified Oxylipins from the Shipworm Symbiont Teredinibacter turnerae

  • Noel M. Lacerna,
  • Cydee Marie V. Ramones,
  • Jose Miguel D. Robes,
  • Myra Ruth D. Picart,
  • Jortan O. Tun,
  • Bailey W. Miller,
  • Margo G. Haygood,
  • Eric W. Schmidt,
  • Lilibeth A. Salvador-Reyes and
  • Gisela P. Concepcion

20 December 2020

The bioactivity-guided purification of the culture broth of the shipworm endosymbiont Teredinibacter turnerae strain 991H.S.0a.06 yielded a new fatty acid, turneroic acid (1), and two previously described oxylipins (2–3). Turneroic acid (1) is...

  • Article
  • Open Access
12 Citations
5,197 Views
18 Pages

Heteroexpression of Aspergillus nidulans laeA in Marine-Derived Fungi Triggers Upregulation of Secondary Metabolite Biosynthetic Genes

  • Ishrat Khan,
  • Wan-Lin Xie,
  • Yu-Chao Yu,
  • Huan Sheng,
  • Yan Xu,
  • Jia-Qi Wang,
  • Sanjit Chandra Debnath,
  • Jin-Zhong Xu,
  • Dao-Qiong Zheng and
  • Wan-Jing Ding
  • + 1 author

18 December 2020

Fungi are a prospective resource of bioactive compounds, but conventional methods of drug discovery are not effective enough to fully explore their metabolic potential. This study aimed to develop an easily attainable method to elicit the metabolic p...

  • Article
  • Open Access
9 Citations
3,590 Views
23 Pages

Extraction Improvement of the Bioactive Blue-Green Pigment “Marennine” from Diatom Haslea ostrearia’s Blue Water: A Solid-Phase Method Based on Graphitic Matrices

  • William Bélanger,
  • Alexandre A. Arnold,
  • François Turcotte,
  • Richard Saint-Louis,
  • Jean-Sébastien Deschênes,
  • Bertrand Genard,
  • Isabelle Marcotte and
  • Réjean Tremblay

18 December 2020

The compound “marennine” is a blue–green pigment produced by the benthic microalgae Haslea ostrearia, with pathogenicity reduction activities against some bacteria and promising potential as a natural pigment in seafood industries....

  • Review
  • Open Access
24 Citations
5,609 Views
20 Pages

18 December 2020

Globally, the burden of neurodegenerative disorders continues to rise, and their multifactorial etiology has been regarded as among the most challenging medical issues. Bioprospecting for seaweed-derived multimodal acting products has earned increasi...

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Mar. Drugs - ISSN 1660-3397